唑

Due to a variety of biological activity, benzotriazole derivatives receive wider and wider spread attention about their synthesis as well as the activity research.

苯并三氮唑类衍生物由于具有多种生物活性，关于它们的合成以及活性研究受到越来越广泛的关注，因此，苯并三氮唑及其衍生物的研究与开发具有重要的意义。

Benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene]dichloro(2-methylpyridine)ruthenium (62), benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene] dichloro(2,4-dimethylpyridine)ruthen ium (63) introduce ortho substituted pyridine as dissociating ligand to weaken Ru-N bondand accelerate dissociation of pyridine derivative ligand through steric hindrance.

在钌卡宾配合物[1，3-二-(2，6-二甲苯基)-4，5-二氢咪唑基]-苯亚甲基-(2-甲基吡啶)-二氯合钌(62)，1，3-二-(2，6-二甲苯基)-4，5-二氢咪唑基1-苯亚甲基-(2，4-二甲基吡啶)-二氯合钌(63)中，邻位取代的吡啶作为解离配体，通过邻位基团的空间效应削弱钌-氮配位键，使配体更易解离，提高了催化剂的初活性。

5H-Thiazolo[3,2-a]pyrimidine can be efficiently prepared by the reaction of dihydropyrimidine-2-thione withα-bromoacetone,in water media.

在此反应体系中，2-氨基-5-芳氧亚甲基-1，3，4-噻二唑与丙烯酸酯反应，意外的得到环合产物—5H，6H-[1，3，4]噻二唑并[1，2-a]嘧啶-7-酮类衍生物。

Methods To divide 147cases cacodontia which need root-canal therapy into two groups randomly, 90 cases in the Tinidazole root-canal disinfect group, 57 cases in the Tinidazole root-canal filling group.

方法对147例做根管治疗的患者随机分为两组，替硝唑根管消毒组90例，替硝唑根管充填组57例。

1-phenyl-3-methyl-4-caprylpyrazolone-5 was synthesized from 1-phenyl-3-methyl-pyrazolone-5 and caprylyl chloride, and some extraction parameters were investigated such as the acidity, the concentration of Sr, the time of the extraction and the thinners.

通过1-苯基-3-甲基-吡唑啉酮-5与辛酰氯合成萃取剂1-苯基-3-甲基-4-辛酰基吡唑啉酮-5，并对其萃取Sr的影响因素，如酸度、Sr浓度、萃取时间和稀释剂等进行研究。

In this paper,many achievements of studying on the synthesis,thermal decomposition properties and characteristics of the energetic complexes based on high-energetic compounds containing many nitrogen atoms such as carbohydrazide and 5-nitro-2,4-dihydro-3H-1,2,4-triazol-3-one as well as tetrazole,etc.

概述了以高能多氮直链化合物如碳酰肼，富氮杂环化合物如三唑、四唑类为配体的配合物的合成、热行为以及性能的研究情况，同时简要地从分子或原子结构描述了一些其他多氮含能配体如肼、肼基甲酸甲酯等所形成的配合物的晶体结构以及热分解行为，并对含能配合物的发展方向进行了展望。

RESULTS: Treated for a same period （3 d）, the inhibitory effect of MG132 on PC12 ceil proliferation enhanced with the increment of the concentration of MG132（0, 1, 2.5, 5, 10, 20 μmot/L）.

用不同浓度的MG132处理PC12细胞3d，通过3-（4，5-二甲基噻唑-2）-2，5-二苯基四氮唑溴盐微量比色法检测MG132对PC12细胞增殖的影响，通过姬姆萨染色法和流式细胞术检测MG132对PC12细胞凋亡的影响。

Our company supply raw materials and related intermediates as follows: Second dibutyryl cAMP calcium, voriconazole, terbinafine, vecuronium amines, cAMP, thiamphenicol, a chlorophenol hydrochloride esters, card network sodium phosphate tilmicosin, foscarnet, lornoxicam, Tilmicosin, Cephalosporium aspirin acid, ceftiofur hydrochloride, ceftiofur sodium, Ozagrel, ondansetron hydrochloride ketones, hydroxyurea, ticarcillin sodium, telmisartan, esmolol hydrochloride, hydrochloric acid Daguan Nikkomycin, adefovir dipivoxil, buflomedil hydrochloride, granisetron hydrochloride, warfarin sodium,-methyl gabexate acid, nicergoline, pantoprazole sodium,·, tegafur, cefepime hydrochloride, vecuronium bromide, hydrochloric acid meclofenoxate, sertraline hydrochloride, Cefonicid amine salt, aztreonam, ticarcillin, cefdinir, cefodizime sodium, sodium ferulate, colloidal pectin secretion, 2,3 - cyclopentene and pyridine, Piperacillin acid, cefetamet US-acid, hydrochloride Cefmenoxime ,3-TZ, 2 - deoxy-D-glucose, two-amidine urea benzene, sodium Cefonicid, Cefonicid intermediates, ester Cefamandole sodium, Cefalotin acid, intermediates cefpirome, cefepime sulphate, cefepime intermediate nucleus of cefepime, cefpirome nucleus, Cefamandole sodium, ceftriaxone new active ester, oxaliplatin, cyclophosphamide vary gland amines, polyene match him.

我公司供应的原料药及相关中间体为：二丁酰环磷腺苷钙、伏立康唑、盐酸特比萘芬、维库溴胺、环磷腺苷、甲砜霉素、盐酸甲氯酚酯、卡络磺钠、磷酸替米考星、膦甲酸钠、氯诺昔康、替米考星、头孢匹胺酸、头孢噻呋盐酸盐、头孢噻呋钠、奥扎格雷、盐酸恩丹西酮、羟基脲、替卡西林钠、替米沙坦、盐酸艾司洛尔、盐酸大观霉素、阿德福韦酯、盐酸丁咯地尔、盐酸格拉司琼、华法林钠、甲磺酸加贝酯、尼麦角林、泮托拉唑钠、普拉洛芬、替加氟、盐酸头孢吡肟、维库溴铵、盐酸甲氯芬酯、盐酸舍曲林、头孢尼西胺盐、氨曲南、替卡西林、头孢地尼、头孢地嗪钠、阿魏酸钠、胶体果胶泌、2，3-环戊烯并吡啶、哌拉西林酸、头孢他美酸、头孢甲肟盐酸盐、3-TZ、2-脱氧-D-葡萄糖、双脒苯脲、头孢尼西钠、头孢尼西中间体、头孢孟多酯钠、头孢噻吩酸、头孢匹罗中间体、头孢吡肟硫酸盐、头孢吡肟中间体、头孢吡肟母核、头孢匹罗母核、头孢孟多钠、头孢曲松新型活性酯、奥沙利铂、异环磷腺胺，多烯他赛。

In this dissertation, I will represent my studies on the nitration of Chalcone derivatives, reaction of epoxide ketone, and the aromatization of 3,5-disubstitued 2-isoxazolines with nitric oxide.

本文主要研究了：(1)NO与查尔酮及其衍生物的硝化反应，反应以较高的产率得到了a-硝基化合物；(2)NO对环氧酮的开环反应，反应生成了顺式羟基硝酸酯；(3)3，5-二取代的-2-异恶唑啉在NO作用下可以发生芳环化反应，生成了对应的2-异恶唑化合物。

In order to find biologically active urea compounds,seven new N-[5-(3-pyridyl)-1,3,4-thiadiazol-2-yl]-N'- urea derivatives were synthesized by the reaction of 2-amino-5-(3-pyridyl)-1,3,4-thiadiazole with aroylazides,which were prepared starting from carboxylic acids,ethyl chloroformate and sodium azide by one-pot procedure.

为了寻找高生物活性的脲类化合物，通过2-氨基-5-(3-吡啶基)-1，3，4-噻二唑与酰基叠氮化物反应，设计合成了7个新的N-[5-(3-吡啶基)-1，3，4-噻二唑-2-基]-N'-取代苯基脲，其中芳酰基叠氮化物是以芳酸、氯甲酸乙酯、叠氮化钠为起始原料采用&一锅法&所制得。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。