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Two representative compounds have been determined by X-ray crystallography. The best ratio of reactants, the adequate reaction temperature and solvent have been found by contrast experiments.4. The better photoreaction conditions and irridation times have been confirmed through the different photoreaction results. It is the first time that fifty quinazoline derivatives with biological activity and four photooxidation products with urea functional groups have been obtained by photochemistry method. Two representative compounds, quinazoline derivatives and photooxidation products, have been determined by X-ray crystallography, respectively.

通过实验对比我们找到了较佳的反应物的投料比、反应温度和反应所用的溶剂。4、根据不同条件下的光反应结果,确定了硫脲衍生物的相对较好的光反应条件和光照时间,首次利用光化学手段成功得到50个具有生物活性的喹啉衍生物和4个具有脲基官能团的光氧化的产物,测定了两个具有代表性的喹啉和光氧化的产物的晶体结构。

Subsequently, 3-(substituted-phenyl)isoxa- zole-5-methylamino-4(3H)-quinazoline derivatives 6a~6e were obtained by solid-grinding 5a~5e and 4 under the basic Al2O3 at room temperature.

4与5a~5e在碱性氧化铝作用下固相研磨合成了5种未见文献报道的新型的含异噁环的喹啉衍生物6a~6e。

Methods 83 cases with documented peptic ulcer and Hp infection by endoscopic examination and rapid urease test were randomized to receive rabeprazole or omeprazole-based triple therapy regimens for 10 days.

83例经胃镜检查确诊的消化性溃疡,并经快速尿素酶法和组织学测定为Hp阳性患者,随机分为雷贝拉组和奥美拉组。

Methods: Eighty-six patients with peptic ulcer and Hp infection confirmed by gastroscopy and right urease test were randomized to receiving rabeprazole (46 cases)-or omeprazole (40 cases)-based triple therapy regimen for 10 days.

86例经胃镜检查确诊,并经快速尿素酶法和组织学测定为Hp阳性的消化性溃疡病人,随机分为雷贝拉组(46例)和奥美拉组(40例)。

METHODS: A single oral dose of 40 mg rabeprazole capsules or tablet was given to 18 healthy male volunteers in double alterrative periode for an open randomized cross-over test.

18名男性健康志愿者随机分2组,按双周期交叉口服雷贝拉的2种制剂,剂量40mg,用高效液相色谱法测定给药后不同时间点血浆中雷贝拉的浓度,计算2种制剂药动学参数和相对生物利用度,并评价其生物等效性。

Furthermore, a convenient procedure for synthesis of unsymmetric squarylium cyanies has been developed. We find the particular reactiveness between benzotellurazolium lodide and squaric acid: only 1: 1 condensation is involved in this reaction. The resultant can condense easily with benzothiazolium iodide to give unsymmetric squarylium dye of unique component.

研究了苯并碲季铵碘盐与方酸的特殊反应性,发现它们只发生1:1缩合,缩合产物可与苯并噻碘盐反应生成染料,从而提供了制备单一组分的不对称方酸碲菁染料的简便方法。

With MS medium as basic medium, the effect of PP333 on the growth and transplant of Robinia pseudoacacia cv idaho plantlets was studied in its subculture added PP333 with different concentrations.

以MS为基本培养基,添加不同浓度的多效进行香花槐试管苗的继代培养,研究了多效对香花槐试管苗生长及移栽的影响。

When the catalyst was triethylamine, the water produced in condensation of isopropanolamine or ethanolamine and butanone was removed with benzene by water segregator, then the dichloroacetyl chloride was dropped.

利用异丙醇胺、乙醇胺、丁酮和二氯乙酰氯为原料,分别合成了两种除草剂安全剂Ⅰ∶3-二氯乙酰基-2,5-二甲基-2-乙基-1,3-噁烷和Ⅱ∶3-二氯乙酰基-2-甲基-2-乙基-1,3-噁烷。

The compounds are represented by the structural Formula 1, Chemical formula should be inderted here as it appears on the abstract in paper form. a prodrug thereof, or any pharmaceutically acceptable salt, solvate, isomer or racemic mixture of the compound or said prodrug wherein R1 is heteroaryl, N-arylaminocarbonyl, N-heteroarylaminocarbonyl, benzimidazolyl or benzothiazolyl; R15 is present or not and if present is H, aryl, alkyl, arylalky or heteroarylalkyl; A is aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene or heterocycloalkyl wherein said aryl, heteroaryl, cycloalkyl, cycloalkylidene, heterocycloalkylidene and heterocycloalkyl moieties may be substituted or unsubstituted; and B, L, X and R18 are defined herein.

所述化合物用结构式1表示,包括其前药或所述化合物或所述前药的任何药学上可接受的盐、溶剂合物、异构体或外消旋混合物,其中R 1 为杂芳基、N-芳基氨基羰基、N-杂芳基氨基羰基、苯并咪基或苯并噻基;R 15 存在或不存在,如果存在,则为H、芳基、烷基、芳基烷基或杂芳基烷基;A为芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基或杂环烷基,其中所述芳基、杂芳基、环烷基、环烷叉基、杂环烷叉基和杂环烷基部分可被取代或未被取代;B、L、X和R 18 如说明书所定义。

The results indicated 2.0 mg/L of pp333 conduced to multiplication of squama,The best concentration for root growth was 0.5 mg/L.

结果表明:浓度为2.0 mg/L的多效有利于切花百合鳞片芽增殖;多效0.5mg/L为生根的最佳浓度

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