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When proceeding the research of drug identification by ultraviolet spectrophotometry, this paper adopts the approaches below: to identify Metronidazole Buccal Tablets and Potassium Sodium Dehydroandroan Drographolide Succinate by ulviolet maximum absorbent wavelength; to identify Metronidazole Disodium Phosphate for Injection by ulviolet maximum absorbent wavelength and minimum absorbent wavelength; to identify Ceftriaxone Sodium for Injection and Clarithromycin Tablets by retention time of high performance liquid chromatography- ultraviolet spectrophotometry.

通过测定紫外最大吸收波长λ_(max鉴别甲硝口颊片和炎琥宁、测定紫外最大吸收波长λ_(max和最小吸收波长λ_(min鉴别注射用甲硝磷酸二钠,结合高效液相色谱(high performance liquid chromatography-ultraviolet detector,HPLC-UV)中保留时间的测定鉴别注射用头孢曲松钠和克拉霉素片,本文建立了药物鉴别的紫外分光光度法。

The research indicates that:(1) detecting λmax (277nm) can identify Metronidazole Buccal Tablets prepared by Chongqing Medical College;(2) detecting λmax (321nm) and λmin (265nm) can identify Metronidazole Disodium Phosphate for Injection prepared by Chongqing Medical College;(3) detecting tr (6.7min) in HPLC-UV spectrum can identify Ceftriaxone Sodium for Injection prepared by Chongqing Keru Pharmacy Co.;(4) detecting tR (10.2min) 6.7min in HPLC-UV spectrum can identify Clarithromycin Tablets prepared by Harebin Yida Pharmacy Co.;(5) detecting λmax (254nm) can identify Potassium Sodium Dehydroandroan Drographolide Succinate prepared by Hong Kong Yaohen Co..

结果表明:①测定紫外最大吸收波长λ_(max277nm可鉴别重庆医科大学医药研究所制备的甲硝口颊片;②测定紫外最大吸收波长λ_(max321nm和最小吸收波长λ_(min265nm可鉴别重庆医科大学医药研究所制备的注射用甲硝磷酸二钠;③测定HPLC-UV中的保留时间(t_R6.7min)可鉴别重庆科瑞制药股份有限公司制备的注射用头孢曲松钠;④测定高效液相色谱的保留时间(t_R10.2min)可鉴别哈尔滨伊达制药厂提供的克拉霉素片;⑤测定紫外最大吸收波长(又max254nm)可鉴别香港耀恒公司提供的炎琉宁。

It is a method most in use to analyze drugs.This paper chooses the antibiotics intending to be registered as research topics to study their identification, tests and assay by ultraviolet spectrophotometry. These antibiotics includes Metronidazole Buccal Tablets, Metronidazole Disodium Phosphate for Injection, Ceftriaxone Sodium for Injection, Clarithromycin Tablets, Potassium Sodium Dehydroandroan Drographolide Succinate.

本文选择拟注册的抗生素类药物甲硝口颊片、注射用甲硝磷酸二钠(Metronidazole Disodium Phosphate for Injection)、注射用头孢曲松钠(Ceftriaxone Sodium for Injection)、克拉霉素片和炎琥宁(Potassium Sodium Dehydroandroan Drographolide Succinate)为研究对象,应用紫外分光光度法进行鉴别、检查和含量测定研究。

The determination method of furazolidone residue in eggs by high performance liquid chromatography has been developed using matrix solid-phase dispersion and solid-phase extraction technologies for sample pretreatment.

采用基体固相扩散和固相萃取相结合的技术,对鸡蛋中呋喃酮残留进行了提取和净化处理,建立了高效液相色谱法检测鸡蛋中呋喃酮残留量的方法。

Solasodine, which was known to inhibit the synthesis of ergosterol, had a close clustering position with ketoconazole and clotrimazole group.

另外已知澳洲茄胺抑制的是细胞膜上麦角固醇的合成,聚类分析表明它与酮康,克霉的聚类很靠近。

Objective:to compare the efficacy and safety of pantoprazolewith that of omeprazolein patients with reflux esophagitis disease.

目的:评价并与奥美拉比较泮托拉治疗反流性食管炎的疗效和安全性。

Three species of typical fresh algae, Chlamydomonas reinhardtii, Euglena gracilis, Synechococcus leopoliensis, were chosed as the experiment material in order to investigate their biodegradable abilities to triazophos.

使用液液萃取——气相色谱检测的方法测定培养基中三磷的浓度,回收率在84.2%~97.4%之间,相对标准偏差为0.24%~2.48%;藻培养液离心后取上清液用液相色谱检测培养基中三磷的浓度,回收率为99.0%~99.7%,相对标准偏差为0.6%~1.0%。

Treatment options: You can take tinidazole or metronidazole (the time can not exceed 7 days), which is a treatment of anaerobic or facultative anaerobes drugs.

治疗方案:您可以替硝或甲硝(时间不能超过7天),这是一种厌氧或兼性厌氧菌治疗药物。

Fungicides washed with alkaline solution, the choice of the following drugs:① clotrimazole suppository or tablet, 1 time per night, each one or one, deep into the vagina, once a 7;② Saindak Nanjing suppository every night into a vagina, once a 7;③ nystatin suppository or tablet, 1 time per night, each one or 1 (100,000 U ), once a 7 on the 10th;④ meters may be set vagina effervescent tablets, one night, into the vagina, once a 5;⑤ 1% aqueous gentian violet涂擦vagina, 3 to 4 times a week, for 2 weeks, the drug cost, the effect is also very good, but must pay attention to drug concentration, if the drug or administering a drug过浓too frequent and easy to cause chemical vulvitis and epidermal rupture due to drug easily contaminated clothing, now has more clinical less use.

杀菌剂以碱性溶液冲洗后,选用下列药物:①克霉栓剂或片剂,每晚1次,每次1粒或1片,塞入阴道深部,连用7日;②达克宁(硝酸咪康miconazole)栓剂,每晚1粒塞入阴道,连用7日;③制霉菌素栓剂或片剂,每晚1次,每次1粒或1片(10万U),连用7~10日;④米可定阴道泡腾片,每晚1片,塞入阴道内,连用5日;⑤1%龙胆紫水溶液涂擦阴道,每周3~4次,连续2周,药物价廉,效果也很好,但必须注意用药浓度,若药物过浓或用药过频,易引起化学性外阴炎和表皮破溃,因药物易污染衣物,现临床已较少使用。

The synthesized hapten of triazophos was covalently conjugated to bovine serum albumin and ovalbumin respectively to prepare artificial antigen and coating antigen.

将合成的三磷半抗原采用活性酯法分别与牛血清白蛋白和卵清蛋白共价偶联制备突出三磷分子结构特征的人工抗原与包被抗原。

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