哮喘地

Then observe the treatment effects of Jiaomu Oil and dexamethasone on AHR of guinea pigs.

观察椒目油及地塞米松干预后对哮喘豚鼠气道反应性的影响。

The simultaneity use of Xiao Er Chuan Ke Ye and Cang Er Zi San intervening asthma and allergic rhinitis,comparing simply use Xiao Er Chuan Ke Ye,has the predominance in prolonging time of introducing asthma and reducing the frequency of nodding breathe,which indicated that the treatment of allergic rhinitis has great importance in asthma control and lessen the degree of asthma(frequency of rat nodding breath).3,The combination high-dose group has better therapeutic effect than dexamethasone group,all Chuan Ke Ye groups and combination low,medium group in the prevention and control of allergic rhinitis symptoms,reduced airway hyper responsiveness,while in improving breath difficulties combination high-dose group has similar effect with western medicine group,and better effect than all Chuan Ke Ye groups and combination low,medium group.Its efficacy increased with the prolonging of treatment time,but fewer side effects,which makes the application safer and more reliable.4,Xiao Er Chuan Ke Ye combining with Cang Er Zi San can obviously improve the pathological changes in rats with bronchial airway remodeling,reducing the serum TGF-β1,IL-4,ECP levels,increasing the level of serum IFN-γand the imbalance IFN-γ/ IL-4 ratio.

而运用小儿喘咳液合苍耳子散同时干预哮喘与过敏性鼻炎，较之单纯使用小儿喘咳液治疗哮喘，其在延长引喘时间、减少点头呼吸频度等方面有明显的优势，说明过敏性鼻炎的治疗，对于控制哮喘发生，减轻哮喘发作的程度，有着重要的意义。3、大剂量的合方在预防和控制过敏性鼻炎症状、降低哮喘气道高反应性方面疗效较地塞米松对照组、喘咳液各剂量组及合方小、中剂量组更优，而改善呼吸困难方面则与西药组相当，优于喘咳液各剂量组及合方小、中剂量组，且其疗效随着治疗时间的延长而增加，但副作用更少，使用更加安全可靠。4、小儿喘咳液合苍耳子散能明显改善气道重塑大鼠支气管的病理改变，同时降低血清TGF-β1、IL-4、ECP水平，提高血清IFN-γ水平及失衡的IFN-γ/IL-4比值。

Methods 36 moderate and severe bronchia asthma patients were taken as the case group treated with Budesonide (2mg, Bid) inhalation, 33 similar patients were taken as the control; observation was made on the patients recovery and the reduction of glucocorticoid dosage and the patients lung faction changes.

36例中、重度支气管哮喘患者为治疗组，给予吸入布地奈德混悬液2mg bid，对照组为同期收治的支气管哮喘患者33例。观察病情缓解和糖皮质激素减量的天数及肺功能变化。

A special toxin-free butterbur extract has been investigated for the treatment of a variety of illnesses.

Butterbur同时被进行初步的调查用于治疗哮喘和保护胃部损伤，因此能有效地防止溃疡。

Results: 1 The capacity of engulfment of A549 cells started enhancing at the 1h of preincubation with dexamethasone, reached the highest at the 4h of preincubation,At the 8h、24h of preincubation the capacity of engulfment evidently reduced. 2 Glucocorticoid cytosolic receptors antagonist RU38486 inhibited the improved engulfment ability by dexamethasone. 3Phagocytosing apoptotic eosinophils did not change the release of IL-6 and IL-8,but can inhibited the release of IL-6 and IL-8 from A549 cells stimulated by lipopolysaccharide. 4Increasely uptaking by dexamethasone also did not agitate the release of IL-6 and IL-8 from A549 cells. Conclusion: 1Dexamethasome improve the phagocyte capacity for apoptotic eosinophils of A549 cells by glucocorticoid cytosolic receptors, and the effect presents time-dependently. 2Phagocytosis of apoptotic eosinphils can degrade inflammatory reflection, so it is likely to be critical in the control of asthma inflammation.

结果： 1 A549细胞在地塞米松诱导后1小时吞噬能力开始升高，4小时吞噬能力达最高峰，8小时、24小时吞噬能力明显下降 2加入RU38486后抑制了地塞米松所增强的吞噬能力 3凋亡嗜酸粒细胞的吞噬并不能改变A549细胞释放IL-6和IL-8，但能抑制脂多糖刺激A549细胞后IL-6、IL-8的分泌 4地塞米松增加的吞噬也不激发A549细胞释放IL-6和IL-8 结论： 1地塞米松促进A549细胞吞噬凋亡的嗜酸粒细胞是通过A549细胞糖皮质激素胞浆受体发挥作用的，并且具有时间依赖性 2 A549细胞吞噬凋亡的嗜酸粒细胞能降低炎症反应，对哮喘炎症的控制具有重要意义

Methods: The author chose randomly sixty healthy children as the control group and one hundred and sixty children with asthma in acute period before ICS therapy as the experimental group. The experimental group were treated with ICS therapy and then eighty-nine children of this group were followed up for 3 months ,sixty-eight for 6 months and sixty for 12 months. The ICS in the study was budesonide with the trade name as Pulmicort. We adopted swab from the pharynges respectively, inoculated it in agar plate, isolated the bacteria, and evaluated the distribution and variation of the microbial population in pharyngeal portion.

方法随机选择健康儿童60例和支气管哮喘急性发作期患儿160例采取其口咽拭子，并于哮喘患儿在吸入型糖皮质激素(布地奈德，商品名普米克)治疗后分别随访3个月(89例)、6个月(68例)、12个月(60例)分别采取其口咽拭子，接种于琼脂平板，分离细菌，按程序鉴定，观察其咽部菌群的分布及其演变。

Objective To observe the airway remodeling in the respiratory tract of asthmatic SD rats models and the expression of MMP-9/TIMP-1 and compared with the dexamethasone control group in order to find the mechanism of antiasthmatic pills in healing asthma.

目的：通过二次致敏，制成大鼠哮喘模型，探讨气道重塑与MMP-9/TIMP-1表达的关系及平喘丸的干预作用并与地塞米松相对照，力图掀开平喘丸治疗哮喘的机理。

Objective:To approach the effects of psychosocial intervention on the quality of life of asthma patients.

中文摘要目的：探讨心理干预对哮喘患者生活质量的影响，以期为哮喘患者提供一套简便、易行、有效的心理干预方法，更好地提高其生活质量。

With computer image analysis system, the expressions of NF-κB and ICAM-1 and subepithelial collagen deposition were checked.

将40只大鼠随机分为对照组、哮喘组（以卵蛋白激发的大鼠哮喘模型）、布地耐德早期治疗组、布地耐德晚期治疗组，应用免疫组化技术结合计算机病理图像分析系统测定大鼠气道上皮胶原的沉积和气道上皮细胞NF-κB、ICAM-1的相对含量。

BE1 monoclonal antibody can be used to detect basophils in tissue.

BB1单克隆抗体可有效地用于支气管肺组织标本的嗜碱性粒细胞免疫组织化学检测，同时急性发作的致死性哮喘患者气道中嗜碱性粒细胞明显增加，可能与哮喘病情恶化、甚至死亡有关，而非致死性的慢性哮喘患者气道中嗜碱性粒细胞与对照组无异，说明嗜碱性粒细胞可能主要参与哮喘的急性病程。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。