哮喘

Objective To explore the effect of glucocorticoid on disbalance of the Th 1/Th 2 cytokines to investigate the mechanism of treatment of breathing in glucocorticoid in asthmatic patients.

目的 为了解糖皮质激素对哮喘患者Th1 /Th2 类细胞因子水平失衡的影响，探讨吸入糖皮质激素治疗哮喘的机制。

Result:The serum soluble CD86 concentrations in the dual responder group increased from(491.8 F 15.4)IU/ml before allergen inhalation to(603.8 F 19.3)IU/ml 24 h after allergen inhalation.

结果：在吸入变应原后24 h，双相哮喘反应组血清sCD86浓度从(491.8±15.4)IU/ml上升到(603.8±19.3)IU/ml，而单相哮喘反应组sCD86浓度与基础值相比无显著提高。

The changes of the pulmonary function parameters:lung resistance and dynamic lung compliance,were measured to evaluate asthma severity continuously.

实时测量哮喘豚鼠肺功能参数，肺动态顺应性和肺阻力的变化，作为反映哮喘严重程度的指标。

CSs inhibit allergen-induced eosinophilia in blood and sputum, improve AHR and symptoms in asthmatics.

局部使用激素是目前最有效的哮喘抗炎药物，它可改善AHR、减轻抗原诱导的血和痰中Eos数以及哮喘症状。

Objective: To investigate the effects of subcutaneous BCG on the airway inflammation blood and bone marrow eosinophilia, airway mucus secretion and the peripheral blood Thl/Th2 balance at the single-cell level.

研究目的在已建立的小鼠哮喘模型的基础上，观察BCG对哮喘小鼠气道炎症、外周血及骨髓中Eos水平及对气道粘液分泌的影响。

Results: Subjects with severe asthma were more symptomatic,had a lower FEV1, and had more sputum neutrophilia (p = 0.007)and eosinophilia (p = 0.001). Exhaled nitric oxide was similarbetween groups.

本试验证明重度哮喘患者痰中中性粒细胞增多和嗜酸细胞增多更明显，且气道内细胞因子和趋化因子的表达也不同于中度哮喘。

Of these, 209 had recently suffered an asthma exacerbation and 77 had stable disease.

这些人中，209名为哮喘恶化，77名为稳定型哮喘。

Preventing asthma exacerbation is an important goal of asthma management.

预防哮喘的加重是哮喘治疗的重要目标。

This book provides a comprehensive review of clinically relevant topics in occupational asthma written by nationally and internationally recognized experts in the field. This text is an outstanding reference resource for the clinician, clinical scientist or clinical fellow with an interest in workrelated asthma.

本书是职业性哮喘领域多位国内和国际知名专家在各个临床相关课题方面的全面深入的总结，是对职业性哮喘感兴趣的临床医生，临床科学家或低年资临床医生的优秀参考书。

PART FOUR EFFECTS OF MIL-4RA EXPRESSION VECTOR ON ASTHMATIC AIRWAY INFLAMMATION AND TH1/TH2 CELL DISFUNCTION THROUGH INTRAPERITONEAL ADMINISTRATION In the study of part three, we treated the mouse asthmatic model by intratracheal administration with mIL-4RA expression plasmid and observed obvious therapeutic effects. But intratracheal administration belongs to one of the insult therapies.

第四部分：腹腔注射mIL-4RA重组载体对哮喘小鼠气道炎症及Th失衡的干预作用前一部分研究中我们通过气道局部干预途径，即气管内直接滴注的方式，观察到mIL-4RA真核表达质粒对哮喘小鼠具有很好的治疗作用，但气管内滴注毕竟属有创性治疗，存在需要实验条件高，有较大的风险性，不易反复进行等缺点，这势必大大限制其在动物实验及进一步临床研究中的实际应用价值。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。