哌嗪

In this dissertation, the stable radical cation salts ofphenothiazine and 10 - alkylphenothiazine alky=〓(〓 hexachloroantimonate,perchlorate and iodide were prepared by one- electron oxidationwith 2,2,6,6-tetramethyl - 4 -acetyloxypiperidine oxoammoniumhexachloroantimonate, perchloric acid/hydrogen peroxide andmolecular iodine respectively, and they were characteried by UV -Vis spectroscopy and ESR spectroscopy.

本文的主要内容有：吩噻嗪和10-烃基吩噻嗪分别被碘、高氯酸／过氧化氢，2，2，6，6-四甲基-4-乙酰氧基哌啶氧铵六氯锑酸盐氧化为相应的正离子自由基碘盐、高氯酸盐、六氯锑酸盐，并用UV-Vis光谱和ESR波谱进行了鉴定和研究。

However, pretreatment with CP-101,606 (1 mg/kg), a selective antagonist for the NR2B subunit of the N M D A receptor, significantly attenuated catalepsy and the expression of Fos-IR cells in the forebrain after the administration of haloperidol.

受体拮抗剂BD-1407 (3 mg/kg)and α-1肾上腺素能受体拮抗剂哌唑嗪(3 mg/kg)预处理不能影响氟哌啶醇诱导的强直性木僵和Fos-IR细胞表达。

Furthermore, the results of the antibiotics sensitivity test of 38 isolates to 24 kinds antibiotics show that all isolates have presented antibiotic resistance disparately as well as multi-resistance. All isolates are sensitive to Cephalosporins antibiotics and Aminoglycosides antibiotics such as Amikacin, Cefazolin, Cefradine, Cefoperazone, and Ceftriaxone. Thirty-eight isolates are extremely resistant to Penicillins antibiotics, Lincomycins antibiotics, Tetracyclines antibiotics and Macrolides antibiotics such as Midecamycine, Lincomycin, Carbenicillin, Tetracycline, Amoxicillin and so on. Antibiotics sensitivity test provides guidance for antibiotic application and scientific foundation from poultry farms.

按世界卫生组织推荐的Kirby-Bauer菌液涂布法对38株大肠杆菌进行24种抗生素的药物敏感性试验，结果表明：38株大肠杆菌均有不同程度的耐药，而且均表现多重耐药；较为敏感的抗生素是头孢菌素类和氨基糖苷类抗生素，其中以阿米卡星、头孢唑啉、头孢拉定、头孢哌酮和头孢三嗪最为敏感；对青霉素类抗生素、林可胺类抗生素、四环素类抗生素和大环内酯类抗生素耐药严重，其中以麦迪霉素、林可霉素、氨苄青霉素、四环素和阿莫西林耐药性最为严重；药物敏感试验为保定、秦皇岛和北京三个地区养鸡业提供科学的用药指南，为药物防治提供科学依据。

The research indicated that under the compound use of hydroquinone and methyl quinone or independent use of phenothiazines or nitrogen oxygen free radical made the polymerization retarder, opposite-methyl-phenylsulfon made the esterification catalyst, toluol made the backflow including water condition, the acid mellowly compared to when it was 1.15, the production rate of the synthesis methylacrylic acid polyethylene glycol single methyl ether (400) ester may achieve 98.9%, was extremely similar to the overseas product functional group structure.

研究表明，在氢醌、甲醌复合使用或者单独使用吩噻嗪、氮氧自由基哌啶酮作阻聚剂，对甲苯磺酸作酯化催化剂、甲苯作回流带水的条件下、酸醇比为1.5时，合成的甲基丙烯酸聚乙二醇单甲醚(400)酯产率可以达到98.9%，与国外产品官能团结构十分相似。

Intravoneous injection of 0.5mg/kgBW jingsongling cause the 60 minutesrelaxation of goat gastric motor.The effects of jingsongling on the gastric motor ofgoat is major of effects of α2 -adrenoceptor agonist,as well as that of α1 -adrenoceptor agonist,the effects of α1 -adrenoceptor agonist concentrate at thecardic and pylorus;the function of α2 -adrenoceptor exit widely at cardic,pylorus,rumen,reticulum,omasum and abomasum,the function at different part is not the same.The lowestdose of jingsonglinginhibiting the amplitude and frequency of the gastricmyoelectric is 0.01mg/kgBW;the influence of jingsonglingto the gastricmotility of goat is dose-dependent,and the amplitude regain after the frequency ofgastric myoelectriv wave.When the goat revived,the gastric motor function is notreach the level of the normal;the major reason ofjingsongling cause the goat gastricrelaxation is the amplitude renew slowly.The intravoneous injection ofjingsonglingfirst,after 5 minutes,intravoneous injection the antagonist,the effect of prazosin and idazoxan mixed is best,which can fast reversal of theinhibition of jingsongling on the gastric motor of goat,the effects of idazoxan isgood,and the prazosin block the effection of jingsongling is better than that ofxylazine,especially at cardia and pylorus.When intravoneous injection of0.5mg/kgBW idazoxan and/or prazosin only,the amplitude of gastric myoelectric ingoat increases at a certain degree,but the frequency is not changed.

静脉注射0.5mk/kgBW的静松灵引起山羊胃蠕动弛缓长达60分钟；静脉注射0.5mg/kgBW的静松灵对山羊胃蠕动机能的影响是以α2肾上腺素受体作用为主的，兼有α1肾上腺素受体的作用，而且静松灵的α1肾上腺素受体的作用主要集中在幽门和贲门；α2肾上腺素受体的作用广泛存在于贲门、瘤胃、网胃、瓣胃、皱胃和幽门中，不同部位间有功能上的差异；静注0.01mg/kgBW的静松灵是对山羊的贲门、瘤胃、网胃、瓣胃、皱胃和幽门的肌电波频率和振幅均产生影响的最低剂量；静注一定剂量的静松灵对山羊胃蠕动的抑制作用与剂量呈相关性；而且山羊胃肌电波振幅的恢复比肌电波频率的恢复慢；苏醒时山羊的胃蠕动机能尚未恢复到正常状态；静松灵引起山羊胃弛缓的主要原因是由于胃肌电波的振幅恢复慢；静注0.5mg/kgBW的静松灵，5分钟后静注0.5mg/kgBW的拮抗剂时，咪唑克生+哌唑嗪的作用最好，能迅速地逆转静松灵对山羊胃蠕动的抑制作用，咪唑克生也有很强的拮抗作用，而哌唑嗪对静松灵的拮抗效果好于对隆朋的拮抗；单独静注0.5mg/kgBW的咪唑克生和/或哌唑嗪时，山羊的瘤胃、网胃、瓣胃、皱胃、贲门和幽门的肌电波振幅有一定程度的增强，而肌电波频率未见变化。

The clinical efficacy and safety ofpipotiazine palmitate is better.

哌泊噻嗪对精神分裂症的疗效较好，副作用较少。

Phenothiazines were also oxidized byiodine and 2, 2, 6, 6- tetramethyl - 4 - acetyloxypiperidineoxoammonium hexachloroantimonate to radical cations in the cavityof β-cyclodextrins in aqueous solution.

以吩噻嗪衍生物为底物，2，2，6，6-四甲基-4-乙酰氧基哌啶氧铵六氯锑酸盐、碘为氧化剂，二者在水相中β-环糊精腔内发生了单电子转移反应，产生了吩噻嗪衍生物正离子自由基。

To determine whether α1 and α2-adrenoceptors are located postsynaptically on renal vascular smooth muscle, a new method was developed as the following: the right renal vascular beds in the pithed rats were perfused with blood drawn from carotid artery at constant rate by a pump.

本实验用颈动脉血恒速满流毁脑脊髓大鼠单侧肾脏的方法，观察了高度选择性α_1受体阻断剂哌唑嗪和α_2受体阻断剂育亨宾与去甲肾上腺素、肾上腺素及电刺激肾交感神经对肾血管平滑肌的相互作用。哌唑嗪明显抑制电刺激引起肾灌流压升高，但尚存留一小部分既不能被增加哌唑嗪的剂量所阻断也不能被育亨宾所阻断。

A novel hydroxyl terminated aminosilicone oil was synthesized using octamethylcyclo tetrasiloxane (D4) and the hydrolysis product of γ-piperazinepropylmethyldimethoxysilane (HD-110) as raw material and potassium hydrate as catalyst.

以八甲基环四硅氧烷(D4)、γ-哌嗪基丙基甲基二甲氧基硅烷(HD-110)水解物为原料，在氢氧化钾催化下，制备了羟基封端的新型氨基硅油。

Since the syntheses of vanadium phophitesin the presence of piperazinium cation as structural director by Zubieta et al., thegreat interest in the synthesis of new transition metal phosphites has been aroused.

自从 Zubieta 实验小组以哌嗪分子作为结构导向剂合成了第一个亚磷酸钒化合物之后，过渡金属亚磷酸盐化合物的合成引起了人们极大的兴趣。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。