哌啶

The invention relates to a preparation method of chiral alpha-alkenyl-alpha'-alkyl piperidine and relative N-Cbz derivative and an application.

本发明涉及一种手性α-烯基-α'-烷基哌啶及其N-Cbz衍生物的制备方法和应用。

Firstly, we selected the catalyst for piperidine oxidation reaction, and obtained the compound catalyst of silicon tungsten molybdic acid.

首先就哌啶醇催化氧化合成TEMPO反应使用的催化剂进行筛选，得出催化效果显著的硅钨钼酸与乙二胺四乙酸复合催化剂。

Piperidine alkaloids are widespread in nature and many piperidine-ring containing compounds exhibit significant biological activities.

中文摘要：含哌啶环化合物大多具有重要的生理活性，在医药、生化和临床上具有广阔的应用前景。

In this thesis, we developed a new method to construct 2, 3, 6-trisubstituted piperidines using enantiopure -amino acid derivatives as the starting material and applied them to the synthesis of some piperidine alkaloids which showed interesting physiological activities.

本论文中，我们从非手性原料出发，通过手性胺对、(-不饱和酯的Michael加成来获得光学纯的-氨基酸酯，发展了一种构建2、3、6-三取代哌啶环的方法，并利用这种方法合成了一些具有重要生理活性的生物碱类天然产物。

Aim According to the targets of 5-HT transporter and 5-HT2A receptor, a series of N -indolalkyl piperidine derivatives and their analogues were synthesized and tested for their biological activities.

摘要摘 要：目的以5-羟色胺转运体和5-HT2A受体为靶点，设计合成 N -吲哚烷基哌啶类化合物及其类似物，研究它们的体内外生物活性。

Pharmaceutical Industry for the production of Bicyclohexane Piperidine BENZTROPINE Dihydrobrohide, diphenhydramine hydrochloride salt.

医药工业中用于生产双环己哌啶、苯甲托品氢溴酸盐，苯海拉明盐酸盐等。

We discussed the syntheses of two different types of plant alkaloids in this thesis. In part A, we aimed at total syntheses in two kinds of aporphine alkaloids, lirioferine and boldine. In part B, we developed a tactic about radical cyclization in polyhydroxylated piperidine synthesis.

中文摘要本篇论文中探讨了两种不同种类植物碱的合成，在A部分中，我们针对阿朴吩类天然物中的鹅掌楸啡碱与波儿丁碱做了各自的全合成研究；在B部分中，我们发展了一种自由基环化策略运用在含多羟的哌啶类化合物之合成上。

The reactions of several phenols and 2, 2, 6, 6-tetramethyl-4-substituted piperidine oxoammonium salt have been studied. It was found that these oxoammonium salts are new facile reagents for phenolic coupling.

应用2，2，6，6-四甲基哌啶氧铵盐实现了酚类的氧化偶联反应：对位取代的酚类底物得到邻位-邻位偶联产物；2，6-二取代的酚类底物得到对位-对位偶联产物；2，4，6-三取代的阻碍酚类底物得到苄位氧化偶联产物。

The piperidine and its ramification selected as raw material to synthesis α-aminonitriles were studied in detail firstly. The oxidation potentials of the amines were determined through the liner sweep voltammetry study.

首先详细研究了以哌啶及其衍生物作为合成原料，通过极化曲线法确定了其氧化电位，并首次发现了氧化电位与1H NMR的化学位移之间的相关性。

The other for: safrole, sassafras oil, safrole different 82 yuan / kg; 1 - phenyl -2 - propanone 2,500 yuan / kg; 3.4 dioxane methylene diphenyl -2 - propanone 7200 yuan / ton; Piperonal 1,000 yuan / kg; N-acetyl-o-amino benzoic acid 11500 yuan / ton; anthranilic acid 15,500 yuan / ton; Phenylacetate 15,000 yuan / ton; acetic anhydride 9900 yuan / ton; trichloromethane 4100 yuan / ton ; anhydrous ether 8500 yuan / ton; piperidine 58000 yuan / ton; methyl ethyl ketone 10,000 won / ton; sulfate 1,200 yuan / ton; hydrochloride 400 yuan / ton; ethanol 4200 yuan / ton.

另供：黄樟素、黄樟油、异黄樟素82元/公斤；1-苯基-2-丙酮2500元/公斤；3.4 亚甲基二氧苯基-2-丙酮7200元/吨；胡椒醛1000元/公斤；N-乙酰邻氨基苯酸11500元/吨；邻氨基苯甲酸15500元/吨；苯乙酸15000元/吨；醋酸酐9900元/吨；三氯甲烷4100元/吨；无水乙醚8500元/吨；哌啶58000元/吨；甲基乙基酮10000元/吨；硫酸1200元/吨；盐酸400元/吨；无水乙醇4200元/吨。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。