哌啶

The final product Rimonbant was then obtained in 64% yield via chlorination of the acid with oxalyl chloride followed by treatment of the resultant acyl chloride with 1-aminoperidine.

酰氯与1-氨哌啶在三乙胺存在下缩合生成目标产物利莫那班，产率64%。

Fourteen unreported N-substituted piperidin-4-one oxime ethers derivatives were synthesized withsubstituted benzylamines or phenethylamine as raw materials via a series of Michael addition, Dieckmann condensation, hydrolysis decarboxylation reactions, oximation a...

以取代苄胺或苯乙胺为起始原料，依次经Michael加成，Dieckmann缩合，水解脱羧，肟化和醚化等多步反应合成了14个未见文献报道的N-取代哌啶酮肟醚衍生物。

Cis dichloroamine (4 amino 2,2,6,6 tetramethylpiperidine 1 oxyl) platinum(abbreviated to HJ5) is a novel platinum anticancer compound which has prospects for research and application.

顺 二氯一氨(4 氨基 2 ，2 ，6 ，6 四甲基哌啶 1 氧自由基)合铂(简称HJ5 )是一种有研究与应用前景的新型铂抗癌配合物。

There are currently three kinds of LFRPs, i.e., 2,2,6,6-tetramethylpiperi- dinyl- N -oxyl mediated system, atom transfer radical polymerization and RAFT-based (reversible addition-fragmentation chain transfer reaction) radical polymerization.

迄今为止，已有稳定自由基如2，2，6，6-四甲基哌啶氮氧游离基调控的体系、原子转移自由基聚合体系和可逆加成-裂解链转移聚合体系问世。

We screened a set of Lewis base organocatalysts derived from chiral pipecolinic acid and tert-butanesulfinamide for the reduction of-N-Cbz-1- phenylpropenamine, including newly designed ones and some of those previously developed in our lab. However, only moderate stereoselectivities, albeit high yields were obtained.

在本课题组前期研究的基础上，我们筛选并设计了一系列以手性哌啶酸和叔丁基亚磺酰胺为母体的有机小分子路易斯碱催化剂，它们能催化三氯氢硅对-N-苄氧羰基-1-苯基丙烯胺的不对称还原，获得很高的收率和中等的对映选择性，并且具有很好的底物普适性。

In this paper four watery UV photoinitiators were studied and synthesized through a four-step process. They were l-(4-aminophenyl)-2-piperidino-1-propanone dihydrochloride, 1 -(4-aminophenyl)-2-morpholino-1 -propanone dihydrochloride, 1 -(4-aminophenyl)-2-diethylamino-1 -propanone dihydrochloride, 1 -(4-aminophenyl)-2-burylamino-1-propanone dihydrochloride, which have not been reported in any literatures till now.

本文通过四步反应合成了目前未见报道的四种水性紫外光引发剂：1-(4-氨基苯基)-2-哌啶基-1-丙酮盐酸盐、1-(4-氨基苯基)-2-吗啉基-1-丙酮盐酸盐，1-(4-氨基苯基)-2-二乙胺基-1-丙酮盐酸盐、1-(4-氨基苯基)-2-正丁胺基-1-丙酮盐酸盐。

Objective: To observe the effects of haloperidol on action potentials in rabbit cardiac Purkinje fibers exposed to abnormal extracellular potassium concentrations.

目的：观察氟哌啶醇对胞外钾离子浓度异常状态下兔浦肯野纤维细胞动作电位的影响。

Based on the investigation of the transesterification between dimethyl sebacate and 1,2,2,6,6-pentamethyl-4-piperinol, the synthetic technologies of Tinuvin292 and Tinuvin 765 were established. The two kinds of hindered amine light stabilizers were obtained in the yield of 93.3% and 92.4% respectively and qualified as the advanced level of the kindred overseas products.2. The synthetic technology of Tinuvin123 was studied and established. Using 2,2,6,6-tetramethyl-4-piperinol as the starting material, the product was synthesized successfully through oxidation, free-radical reaction and transesterification in overall yield of 57.6%.

本文研究建立了三个受阻胺类光稳定剂的合成工艺，探索了聚合型受阻胺类光稳定剂生产过程中不溶性副产物产生的原因，并设计、合成了一系列具有抑菌活性的新型受阻胺类光稳定剂。1、在研究癸二酸二甲酯与1，2，2，6，6-五甲基哌啶醇的酯交换反应的基础上，建立了受阻胺类光稳定剂Tinuvin292、Tinuvin765的合成工艺，分别以93.3%和92.4%的收率得到了光稳定剂Tinuvin292、Tinuvin765，所得产品质量达到了国外同类产品的水平。2、研究建立了受阻胺类光稳定剂Tinuvin123的合成工艺。

Transesterification between dimethyl sebacate and 1,2,2,6,6-pentamethyl-4-piperidinol was studied with tetraisopropyl orthotitanate ,lithium amide and di-n-octyltin oxide used separately as catalysts.

对癸二酸二甲酯与1，2，2，6，6-五甲基哌啶醇的酯交换反应进行了研究；分别考察了四异丙基钛酸酯、氨基锂、氧化二辛基锡3种催化剂的性能；采用氢核磁共振确定了产物的结构；考察了以四异丙基钛酸酯为催化剂时反应温度、反应时间、原料配比和催化剂用量对反应的影响。

The synthetic technologies of three hindered amine light stabilizers were established, the reason for the insoluble side products formed in the production of polymerized hindered amine light stabilizers were studied, and a series of novel hindered amine light stabilizers with antibacterial properties were designed and synthesized in this present paper.1. Based on the investigation of the transesterification between dimethyl sebacate and 1,2,2,6,6-pentamethyl-4-piperinol, the synthetic technologies of Tinuvin292 and Tinuvin 765 were established. The two kinds of hindered amine light stabilizers were obtained in the yield of 93.3% and 92.4% respectively and qualified as the advanced level of the kindred overseas products.2. The synthetic technology of Tinuvin123 was studied and established.

本文研究建立了三个受阻胺类光稳定剂的合成工艺，探索了聚合型受阻胺类光稳定剂生产过程中不溶性副产物产生的原因，并设计、合成了一系列具有抑菌活性的新型受阻胺类光稳定剂。1、在研究癸二酸二甲酯与1，2，2，6，6-五甲基哌啶醇的酯交换反应的基础上，建立了受阻胺类光稳定剂Tinuvin292、Tinuvin765的合成工艺，分别以93.3%和92.4%的收率得到了光稳定剂Tinuvin292、Tinuvin765，所得产品质量达到了国外同类产品的水平。2、研究建立了受阻胺类光稳定剂Tinuvin123的合成工艺。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。