哌啶

Excited triplet state of [60]fullerene containing piperidinoxanthate dyad is at 690nm, which has lifetime of 23.7xs in Ar-saturated benzonitrile, whereas that ofparent C60 is at 750nm, with lifetime of 50s, indicating that excited triplet state of

富勒烯C_(60)哌啶黄原酸酯稠合体激发三线态的最大吸收峰在690nm，相对于纯C_(60)发生蓝移用532nm激光激发后，富勒烯C_(60)哌啶黄原酸酯稠合体激发三线态的最大吸收峰在690nm，相对于C_(60)的750nm发生蓝移，在氩气饱和的苯腈中寿命23.7μs，比C_(60)的55μs短，表明环加成反应连接的哌啶黄原酸酯部分具有吸电子性质。

We provide intermediates of Methylphenidate HCl: 2-Phenyl-2-(2-Piperidyl) Acetamide; 2-Phenyl-2-(2-Piperidyl) Acetic Acid; Series of Benzoic Acid、Benzonitrile; Other pharmaceutical intermediates.

提供盐酸利他林中间体：2-苯基-2-(2-哌啶基)乙酰胺；2-苯基-2-(2-哌啶基)乙酸；苯甲酸、苯甲腈系列及其他医药中间体。

The UV-Visible absorption spectra and the fluorescence emission spectra of sixteen tetra-substituted metallo-phthalocyanine complexes {R4PcM, where R=2-［4-(2-sulfonic ethyl)piperazin-1-］ ethoxyl, 2-(piperidin-1-yl)ethoxyl; substitution position at α-position and β-position of phthalocyanine ring; M=Zn, Ni, Coand Cu} were measured.

报道了16种含哌嗪或含哌啶四取代酞菁金属配合物{R4PcM， R=2-［4-(2-磺基乙基)哌嗪-1-基］乙氧基、 2-(哌啶-1-基)乙氧基；取代位置分别在α位和β位； M=Zn， Ni， Co， Cu}的UV-Vis吸收光谱和荧光发射光谱的测定，探讨了中心金属离子、取代基种类及其取代位置、溶剂等因素对酞菁金属配合物UV-Vis吸收光谱和荧光发射光谱性质的影响。

A selective and mild PS-DIB/ionic-liquid immobilized 2, 2, 6, 6-tetramethyl-piperidin-4-ol-N-oxyl catalytic oxidation procedure of alcohols to the corresponding aldehydes and ketones in ionic liquid BF4 at room temperature was developed. The oxidant PS-DIB was prepared via the iodation and acetylation of polystyrene resin. For the preparation of the ionic-liquid immobilized TeMPO catalyst, 4-(2, 2, 6, 6-Tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide was first synthesized from TeMPO and 1, 4-dibromobutane.

将聚苯乙烯树脂先碘化再乙酰基化，制得了负载型二乙酰氧碘苯作为氧化剂。2， 2， 6， 6-四甲基－N-氧自由基哌啶醇与1， 4-二溴丁烷反应生成4-溴丁氧基－2， 2， 6， 6-四甲基－哌啶－1-氧化物，再与N-甲基咪唑发生季铵化反应，生成的溴化季铵盐与四氟硼酸钠进行离子交换制得氟硼酸型2， 2， 6， 6-四甲基－N-氧自由基哌啶负载离子液体。

A selective and mild PS-DIB/ionic-liquid immobilized TEMPO catalytic oxidation procedure of alcohols to the corresponding aldehydes and ketones in ionic liquid BF4 at room temperature was developed. The oxidant PS-DIB was prepared via Iodation and acetylation of polystyrene resin. For the preparation of the ionic-liquid immobilized TEMPO catalyst, 4-(2,2,6,6-Tetramethyl-1-oxyl-4-piperidoxyl)butyl bromide was first synthesized from 2,2,6,6-tetramethyl-piperidin-4-ol-N-oxyl and 1,4-dibromobutane.

将聚苯乙烯树脂先碘化再乙酰基化，制得了负载型二乙酰氧碘苯(diacetoxyiodo polystyrene，PS-DIB)作为氧化剂。2，2，6，6-四甲基-N-氧自由基哌啶醇(2，2，6，6-tetramethyl-piperidin-4-ol-N-oxyl，TEMPO)与1，4-二溴丁烷反应生成4-溴丁氧基-2，2，6，6-四甲基-哌啶-1-氧化物，再与N-甲基咪唑发生季铵化反应，生成的溴化季铵盐与四氟硼酸钠进行离子交换制得氟硼酸型2，2，6，6-四甲基-N-氧自由基哌啶负载离子液体TEMPO-IL。

METHODS: Patients met with CCMD-Ⅲ criteria of schizophrenia were randomized into two groups: ziprasidone group (n=118) and haloperidol group (n=117) for a double dummy study. The initial doses were 40 mgd^(-1) and 8 mgd^(-1) and the high did not exceed 160 mgd^(-1) and 20 mgd^(-1) for individual of ziprasidone group and haloperidol group respectively.

将235例精神分裂症病人随机分为齐拉西酮组（118例）和氟哌啶醇组（117例），齐拉西酮和氟哌啶醇最低日剂量分别定为40mgd^(-1)，和8mgd^(-1)，最高日剂量分别限定为160mgd^(-1)，和20mgd^(-1)，每日分2次服用。

The target compounds were obtained in high yield through Michael conjugative addition of amines to methyl acrylates, cyclocondensation of the obtained diadducts in the presence of sodium methoxide,and decarboxylation of the cyclocondensation products in acid.

以胺类化合物为原料，与丙烯酸甲酯经过两次Michael加成得到N，N 二丙酸甲酯类化合物，该化合物在甲醇钠存在下进行环合，在酸性条件下脱羧，高收率得到4 哌啶酮类化合物，从而证明了这是一条合成N 取代 4 哌啶酮类化合物的普遍方法。

The study sum up a synthesized route which synthesize (2E,4E)-1,6-bis(3-aminopiperidin-1-yl)hexa -2-4-diene-1,6-dione easily.

总结出了一条反，反-1，6-（R-3-氨基哌啶基）粘糠酰氨的一条合成路线，为国内外同行在合成反，反-1，6-（R-3-氨基哌啶基）粘糠酰氨及其性能研究方面提供了大量得数据，为同行们在合成和更深入的研究反，反-1，6-（R-3-氨基哌啶基）粘糠酰氨提供有限的参考，以互相学习交流。

The effect of reaction temperature,reaction time,materials ratio on the synthesis of piperidine alcohol benzoate ,hindered amine light stabilizer,from piperidine alcohol and benzoyl chloride by direct condensation were studied,and the proper technological conditions were given as follows:the reaction temperature is 95℃;reaction time is 4 h; the mole ratio of reactants,n∶n is 1∶1.4,the amounts of solvent is 40 mL(based 0.1mol piperidine alcohol),the arerage yield ...

王树清，高崇，苯甲酸哌啶醇酯HALS的合成工艺研究研究了以苯甲酰氯和哌啶醇为原料直接缩合合成苯甲酸哌啶醇酯受阻胺光稳定剂时反应温度、反应时间、原料配比等条件对合成反应的影响，确定了最佳工艺条件。最适宜的工艺条件是：反应温度95℃、反应时间6h、原料摩尔比n∶n为1∶1.4，溶剂用量为70mL(相对于0.1mol哌啶醇)，苯甲酸哌啶醇酯的收率为91.05%，产品纯度98.5%。

Piperidinecarboxylic acid is used as the raw material and acetic acid as the acylating agent, followed by the addition of some acetic anhydride in the later stage to get an important organic intermediate n-acetylpiperidine-4 carboxylic acid in the yield of 92%. Toluene is used as the solvent instead of sulfinyl chloride in the acyl chlorination to produce n-acetylpiperidine-4-carbonyl chloride with the yield of 97%.

以4-哌啶甲酸为原料、醋酸为酰化剂，后期加入少量醋酸酐反应得到中间体N-乙酰基哌啶－4-甲酸，收率92%；在甲苯溶剂中进行酰氯化得目标产物N-乙酰基哌啶－4-甲酰氯，收率97%。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐