咪唑

For the synthesis of NHC precursors, there are also several routes: condensation of glyoxal, amines and paraformaldehyde; alkylation of imidazole or monosubstituted imidazole with alkyl halide; annulation of ortho esters and 1,2-diamines; ring closure of hydrazines or amides with acetic anhydride; reduction of thiones with Na/K in THF.

关于N-杂环卡宾前体的合成途径主要有：乙二醛、伯胺和多聚甲醛的缩合反应；卤代烷与咪唑及其取代咪唑的烷基化反应；原甲酸酯与1，2-二胺的成环反应；肼或酰胺与酸酐的环化反应；用Na/K对环硫脲化合物的还原反应。

A rapid and sensitive method using gas chromatography has been developed for the determination of the anthelmintic levamisole in edible tissues of swine , poultry and goats.

左旋咪唑为咪唑并噻唑类广谱驱虫药，具有潜在的基因毒性，我国农业部规定以母体药物形式表现的最高残留限量，在牛、羊、禽类和猪的肌肉、肾脏及脂肪中为10μg／kg，在肝脏中为100μg／kg。

The Soret band in the UV-Vis spectrum of the porphyrin was split because of this effect.

卟啉环流效应对侧链咪唑芳环的影响导致咪唑环上三个氢原子的化学位移向高场移动，且卟啉的紫外－可见光谱的Soret带发生裂分。

Because they have one nitrogen atom with lone pair electrons, benzimidazole compounds are endowed with capability of complex and molecular recognition and they can analogue biological molecule.

苯并咪唑具有一个含孤对电子的氮原子，从而使苯并咪唑类化合物具有很强的配位能力及分子识别能力，可以用于生物分子的模拟。

In this paper, a method of analysis which was based on thin layer chromatography was introduced. Benzimidazole derivative and amine were separated at first.

文中采用薄层层析法分离苯并咪唑衍生物及杂质，首先分离出苯并咪唑衍生物，然后用非水滴定方法分析含量，得到了准确的分析结果。

We developed a simple and efficient method for the synthesis of benzimidazole derivatives in water. Imidazolium salt grafted iodobenzene diacetate containing double features of ionic liquid and iodobenzene diacetate was synthesized.

报道了一种简便高效的苯并咪唑类衍生物的水相合成新方法，合成了兼具离子液体和二醋酸碘苯双重特点的咪唑盐二醋酸碘苯。

The solderability of benzimidazole films on the surface of copper is investigated by solder float test. Several factors which influence solderability of the films are discussed.

采用上锡率法研究了咪唑化合物在铜表面所成保护膜的可焊性，并探讨了咪唑化合物类型、膜厚、再流焊次数及高温热冲击对该膜可焊性的影响。

Three new fluo-rine-containing nitro benzimidazole derivatives were synthesized in the presence of 4-dimethylaminepyridine andtheir structure and configuration were confirmed by elemental analysis, IR, and 1HNMR.

在碱性条件下由2-(4′-羟苯基)-5-取代苯并咪唑与氯乙酸作用得到5个新化合物取代苯并咪唑基苯氧乙酸。

Synthesis of target compounds namely: to vanillic acid as the starting material with methanol under reflux conditions for 4 - hydroxy -3 - p-methyl, then ether, and nitration, reduction, cyclization reaction 6 - methoxy -7 - benzyloxy-quinazoline -4 - one, and then by the chloride in place of aniline, benzyloxy-off, such as etherification reaction of the target compounds; target compounds with the second and third occurrence of substitution reactions of amines by the TM1, that is, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(N, N-diethyl amino) oxy c] quinazoline; with ether occurred Ornidazole reaction of TM2, namely, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(2 - methyl -5 - nitroimidazole) C oxy] quinazoline.

本论文以嘌呤类似物喹唑啉为母核，分别在其4位和7位引入结构多样的取代苯氨基和柔性侧链，设计了一系列4-取代苯胺基-6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉类化合物。目标化合物的合成即：以香草酸为起始原料，与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯，然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮，然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物；目标化合物与二乙胺发生胺取代反应得到了TM1，即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉；通过与奥硝唑发生醚化反应得到TM2，即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

Replacement of one benzimidazole fragment with benzothiazole or benzoxazole and optimization of the structure to create the new frame of the compounds were also carried out with the exception to find more potent compounds. The purpose of design and synthesis of these compounds is to investigate the QSAR of this class of compounds with the inhibition of HCV NS3/NS4A protease and eventually to develop more potent inhibitors.

本文首次采用了丙二酰胺与邻芳二胺在微波辐射下制备对称性双芳并唑甲烷化合物、用芳并唑-2-乙酸乙酯与邻芳二胺在微波辐射下制备非对称性双芳并唑甲烷化合物、用4-取代噻唑-2-乙酸乙酯与邻芳二胺在微波辐射下制备非对称性(4-取代-噻唑-2-基)(1H-芳并咪唑-2-基)甲烷化合物等合成路线，共合成了48个目标化合物，其中41个为新化合物，用~1HNMR，ESI-MS，FT-IR，元素分析对这些化合物进行了全面表征，确定了这些化合物的结构，并对部分化合物进行了~(13)CNMR分析。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。