咪唑

We review this preclinical activity and the evolving implementation of intrathecal midazolam in humans for pain management.

我们对这种临床前试验及近来逐渐在人类应用鞘内咪哒唑仑行疼痛处理的工作进行了回顾。

AIM To compare effects of diazepam and midazolam on the isolated pregnant and nonpregnant rat uterine smooth muscles.

目的 比较苯二氮卓类药物地西泮和咪达唑仑对孕和未孕大鼠子宫平滑肌收缩的影响是否不同。

The reasons for false-positive facet blocks are multifactorial and include placebo response (18–32%) to diagnostic facet interventions, use of sedation, the liberal use of superficial LA, and the spread of injectate to paingenerating structures other than those targeted.166 Although some investigators have disputed this assertion,167,168 it is our belief that not only opioids, but sedatives such as midazolam, can lead to false-positive blocks by interfering with the interpretation of analgesic response (i.e., preventing a patient from engaging in normal activities) and virtue of their muscle relaxant properties.169 In a recent survey conducted in 500 patients receiving facet blocks or epidurals at an outpatient spine center, only 17% requested sedation.170

小关节阻滞性诊断的假阳性结果的原因是多种多样的，包括安慰剂反应(18–32%)，如利用镇静剂，浅表大量应用LA以及注射液外渗到目标外的其他疼痛发生阻滞。虽然有些学者对这种论断持怀疑态度，但是我们认为不论类罂粟碱，咪达唑仑等镇静剂，都可因具有麻醉反应（如可阻止患者从事正常活动）及肌松特点而导致假阳性率。在最近一项500人的研究中，这些门诊患者接受了小关节阻滞或硬膜外阻滞，只有17%患者需要镇静剂。

Objective:To investigate the effect of penehyclidine or atropine combined with midazolam on HR、mean arterial pressure,saturation of blood oxygen(SpO2),hypnosis,conscious-sedation and lapsus memoriae in patients during operation.

目的：观察盐酸戊乙奎醚或阿托品复合咪哒唑仑对病人术中心率，平均动脉压，血氧饱和度（SpO2）及催眠、镇静和遗忘作用的影响效果。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。