咪唑

The reactivities of 1 and other long chain oximes with p nitrophenyl diphenyl phosphate, p nitrophenyl diethyl thiophosphate, and O ethyl ( s β diisopropylaminoethyl) methyl phosphonothiolate were studied.

报道了一种新的高亲核长链咪唑肟N 十四烷基咪唑 2 甲醛肟的设计与合成，并比较了它及其他长链咪唑肟与有机磷酸酯二苯基、对硝基苯基磷酸酯、对硫磷及 Vx 的反应活性。

New ruthenium benzylidene complexes benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene] [k~2-diphenylphosphinoacetato] monochlororuthenium (46), benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene][k~2-3-propionato]monochlororuthenium (47), benzylidene[1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene] [k~2-2-benzonato]monochlororuthenium (48) featured five-membered, flexible six-membered and rigidsix-membered chelating rings respectively are prepared by reactions of complex 41 withcorresponding sodium phosphino-carboxylates. It is confirmed by X-ray crystallographicanalysis that the coordination geometries of complexes 46 and 47 are distorted squarepyramids with phosphino-carboxylate ligands chelating to ruthenium, and the coordinationbetween ruthenium and benzylidene ligands are strengthened.

用二苯基瞵乙酸盐、二苯基膦丙酸盐、二苯基膦苯甲酸盐与钌卡宾配合物41反应合成了三个新的钌卡宾配合物：含五元膦-氧螯合环的1，3-二-(2，6-二甲苯基)-4，5-二氢咪唑基1-苯亚甲基--一氯合钌(46)、含六元柔性膦-氧螯合环的[1，3-二-(2，6-二甲苯基)-4，5-二氢咪唑基1-苯亚甲基--一氯合钌(47)及含六元刚性膦-氧螯合环的[1，3-二-(2，6-二甲苯基)-4，5-二氢咪唑基]-苯亚甲基--一氯合钌(48)。X射线单晶衍射分析证明，配合物46、47都为变形的四方锥构型，膦-氧与钌形成螯合配位，其中苯亚甲基与钌的配位得以加强。

whole brain and most regional metabolism decrease significantly during midazolam anesthesia. thalamus, left prefrontal cortex and cingulated gyrus are most sensitive to midazolam and they may be the primary targets in midazolam anesthesia.

全脑及脑内多数区域cmglu在咪唑安定麻醉后可显著降低，丘脑、左前额叶和扣带回对咪唑安定麻醉更为敏感，可能是咪唑安定麻醉在脑内作用的主要靶区。

Two synthetic routes starting from 1,3-dihydroxyacetone and formamidine acetate as well as imidazole-4,5-dicarboxylic acid as starting material were investigated, and the reductive reaction of ethyl imidazole-4-carboxylate was also investigated.

本文对以1，3-二羟基丙酮和醋酸甲脒为原料和以4，5-二羧酸咪唑为原料合成4(5)-羟甲基咪唑的两条工艺进行了研究并优化，同时对4(5)-羧酸咪唑乙酯的还原反应进行了探索性实验。

Dihydroxyacetone; formamidine acetate; imidazole-4,5-dicarboxylic acid; optimizing process; ethyl imidazole-4-carboxylate; reductive reaction; 4(5)-hydroxymethylimidazole

关键字或关键词组： 1，3-二羟基丙酮；醋酸甲脒；4，5-二羧酸咪唑；工艺优化；4(5)-羧酸咪唑乙酯；还原反应；4(5)-羟甲基咪唑

Its dextrorotatory substant is an antidepressant which does not have the helminthic effect.

所不同的是四咪唑为外消旋体，左旋咪唑是四咪唑经过化学方法处理后拆分而成的左旋体。

It solves the problem of water soluble iminazole and other low molecular easy runs off slowly following water vapor in sulfonated polymeric compound or iminazole composite film, can be used for moderate temperature proton exchange film fuel cell.

采用齐聚物取代咪唑等小分子，可解决磺化聚合物/咪唑复合膜中水溶性的咪唑等小分子易随水汽慢性流失的问题，可应用于中温质子交换膜燃料电池。

An unreported compound 2-cyclopropylbenzimidazolium salt was obtained from 2-cyclopropyl benzimidazole and iodomethane.

以邻苯二胺和环丙基甲酸为原料，以多聚磷酸为催化剂，在微波辐射下合成了环丙基苯并咪唑，用碘甲烷季胺化得到未见文献报道的环丙基苯并咪唑盐，通过苯并咪唑盐与Grignard试剂加成后水解反应制备环丙基甲基酮。

Based on their distinctive optical properties, a method of determining the specific rotation was set up to distinguish these two kinds of chemical materials in the standard for detection of levogyrate preparati.

二者的差别在于盐酸噻咪唑为外消旋体，盐酸左旋咪唑为左旋体，通过利用两种物质的光学特性，在盐酸左旋咪唑制剂的检测标准中设立比旋度测定方法，从而将两种不同的物质加以区

To explore new synthetic methods, we set out a careful investigation of the reaction of benzimidazolium salt with many nucleophilic agents, including the active aromatic compounds and heteratom nucleophilic agents, and found that the quaternary C=N is not so active; when benzimidazolium salt is reacted with big nitrogen nucleophilic agent? phthalimide, it does not give the expected addition product, instead, produces N-alkyl phthalimide through alkyl-transfermation from benzimidazolium salt to phthalimide.

为了开发新的合成方法，研究了苯并咪唑盐与各种亲核试剂（活泼芳环与杂原子亲核试剂）的反应，发现苯并咪唑盐不与活泼芳环及杂原子亲核试剂发生2位加成反应；在与体积较大的位阻型N亲核试剂邻苯二甲酚亚胺反应时，未得到亲核试剂与极化的C＝N的加成产物，而是得到N烷基化的邻苯二甲酰亚胺，进一步研究表明，苯并咪唑盐将1（3）位N上的烷基转移给了邻苯二甲酰亚胺，并讨论了其反应机理和取代基，溶剂效应。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。