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Preparation technology: Mizolastine pass through 100 mesh sieve; HMPCK4MCR、lactose、microcrystalline cellulose、tartaric acid pass through 100 mesh sieve; add all the materials into rapid granulator , add 10%EC alcohol solution as adhesive, obtain roundness granules; Dry them at 50℃, control moisture between 2%~3%; granulation with 18 mesh sieve; add 1% magnesium stearate and admix homogenization; pressing, hardness10kg.

制备工艺为:咪唑斯汀粉碎过100目筛,HPMC K4MCR、乳糖、微晶纤维素、酒石酸氢钾粉碎过100目筛;原辅料加入快速制粒机中搅拌均匀,加入10% EC乙醇溶液为粘合剂,制成圆整的小粒; 50℃烘干,水分控制在2%~3%之间;18目筛整粒;加入1%的硬脂酸镁混合均匀;压片,硬度10kg。

The method of 4-methylimidazole synthesis using pyroracemic aldehyde was selected,and flow chart and operation process were studied.

本文对4-甲基咪唑常用的几种合成方法进行了介绍,对其工业化生产的优缺点进行了对比,最终选定了丙酮醛法,并给出了工艺流程图和操作步骤。

In part Ⅰ, the aquous direct aldol reactions catalyzed by small organo-catalyst—imidazolc were studied in detailed.

本文第一部分详细研究了咪唑为有机小分了催化剂催化水相直接羟醛缩合反应。

One of them can efficient catalysed the alkene in the absence of dear additives by introducing an imidazole in the salen ligand.

其中分子内含咪唑的手性吡咯烷Mn催化剂成功实现了不加昂贵添加剂的情况下高效催化取代色烯环氧化反应。

Results showed that imidazoline was hydrolyzed to amide by ring opening reaction under high temperature.

试验结果表明,高温条件下,咪唑啉发生开环反应,生成了酰胺类物质。

A typical drug aminopyrine, in addition to levamisole, semi-synthetic penicillin may also cause.

典型药物是氨基比林,此外左旋咪唑、半合成青霉素也可引起。

This paper introduced the method that the thiabendazole was synthesized by polyphosphoric acid as solvent.

介绍多聚磷酸作为 4 羧酸噻唑与邻苯二胺溶剂兼脱水剂,合成噻苯咪唑———食品保鲜剂的方法。

The rubbed surface was analyzed with XPS and EPMA, the results shown that the element S, N were as thiadiazole and imidazoline compounds in the rubbed surface film. The tribological properties of surface modified TiO〓 nanoparticles as water base lubrication additive was studied firstly.

用XPS、EPMA对摩擦后的磨斑表面进行了表面形貌,表面膜元素组成,及表面膜中的N〓、S〓电子结合能进行了考察,并与相应母体环化物的N〓、S〓进行了比较,发现摩擦后,磨斑表面膜中的S、N元素,主要是以噻二唑及咪唑啉的形式存在。

Ketoconazole is an imidazole antifungal agent with a broad spectrum of activity against systemic and superficial mycoses.

酮康唑(Ketoconazole,KCZ)属于咪唑类抗真菌药物,对深部真菌和浅表真菌感染均有作用。

Rabeprazole belongs to a class of antisecretory compounds ( benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2 -receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H +/K +-ATPase at the secretory surface of the gastric parietal cell.

雷贝拉唑属于抗分泌药物,苯并咪唑的替代品,质子泵抑制剂。不具有抗胆碱活性和组胺h2受体拮抗活性,但是能够胃壁细胞分泌表面的H +/K +-ATPase而抑制胃酸分泌。

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