周质

For long-term treatments, the rat administered daily by gavages for six weeks, the results of OGTT showed that guava fruit water or alcohol extracts could reduce the plasma glucose level in the diabetic Wistar rats, however there was on significant difference in insulin level among all tested groups. The results of carbohydrate metabolism showed diabetic Wistar rats administered with 200 or 400 mg/kg BW of guava fruit water or alcohol extracts could decrease more than 15% glucose-6-phosphatase and fructose-1,6-bisphosphatase activities, and it also increase more than 12% glucose-6-phosphate dehydrogenase activities to reduce inhibitory hexokinase from reducing glucose-6-phosphate level.

在醣类代谢方面，实验结果发现糖尿病鼠灌食番石榴果实水及乙醇萃取物六周后，肝脏醣质新生作用中丙酮酸合成肝醣之关键酵素glucose-6-phosphatase及fructose-1，6-bisphosphatase的酵素活性会降低15%以上；另一方面肝脏glucose-6-phosphate dehydrogenase酵素活性则明显增加12%以上，并造成glucose-6-phosphate浓度减少，进而降低其对hexokinase的抑制(因为hexokinase受其代谢产物G-6-P的浓抑制)，因此加速肝脏葡萄糖的糖解作用。

After 3 weeks of continuous observation, we found the infection efficiency still keeping in the range of 80%~90%. Conclusion The lentivirus expression vector for β-catenin was successfully constructed.

在感染慢病毒质粒的人毛囊干细胞，当感染复数为10时，感染后48h的感染效率可达80%以上，感染后3周的感染效率仍维持在80%~90%。

Changes of liposome encapsulated psoralen and release rate were detected during a 3 week storage at 4 ℃ for evaluating the stability of the liposomal formulation.

以同浓度的补骨脂素凝胶为对照，用透析法检测补骨脂素脂质体凝胶的体外释药模式，并对其在4 ℃下贮存3周的释药稳定性进行研究。

Methods Solid-tumor-bearing mice were produced with Lewis lung cell and randomly divided into radiation group (n=18) and control group (n=17).The mice in the radiation group were irradiated by 30 Gy X-ray. The expressions of E-cadherin and MMP-9 were detected by immunohistochemical. Results After two weeks of therapy.

建立Lewis肺癌模型，将荷Lewis肺癌的C57BL/6雄性小鼠35只随机分为照射组(n=18)和对照组(n=17)，照射组接受30 Gy的X线肿瘤局部照射，对照组不接受照射，2周后采用免疫组化法检测瘤组织中E-钙黏素蛋白和基质金属蛋白酶－9(MMP-9)蛋白的表达。

MethodsSolidtumorbearing mice were produced with Lewis lung cell and randomly divided into radiation group (n=18) and control group (n=17). The mice in the radiation group were irradiated by 30 Gy Xray. The expressions of Ecadherin and MMP9 were detected by immunohistochemical.ResultsAfter two weeks of therapy.

建立Lewis肺癌模型，将荷Lewis肺癌的C57BL/6 雄性小鼠35只随机分为照射组（n=18）和对照组（n=17），照射组接受30 Gy的X线肿瘤局部照射，对照组不接受照射，2周后采用免疫组化法检测瘤组织中E钙黏素蛋白和基质金属蛋白酶9(MMP9)蛋白的表达。

Fulwiler CE, Saper CP. Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brian Res 1984;319:229-259.[2]Herbert H, Moga MM, Saper CB. Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat. J Comp Neurol 1990;293:540-580.[3]Slugg RM, Light R.

三叉神经脊束间质核(interstitial nucleus of the spinal trigeminal tract， INV)为位于延髓闩平面附近三叉神经脊束内及其周围的一些核团，由中、小型梭形、圆形或卵圆形细胞组成，经三叉神经的分支和迷走、舌咽神经接受外周内脏和躯体感觉信息[6，7]。

In the SMC of the normal rabbits, myofilaments and macula densa were abundant, few mitochondrla and endoplasmic reticulums were found around the nuclear, and the SMC was in the contractive stage. In the SMC of the model rabbits, few myofilaments and macula densa were found, rough surfaced endoplasmic reticulums and mitochondria were abundant, some phagocytosed much lipid and became foam cells, the SMC was in the synthetic stage.

实验12周，高脂组家兔主动脉斑块面积百分比为47.69±12.84％，内膜斑块厚度为0.68±0.08mm，内膜斑块横断面积与中膜面积比值为1.28±0.35；内膜脂质斑块弥漫且较厚，有大量的泡沫细胞堆积，可达8～10层，管腔直径变小，内膜不光滑；泡沫细胞内富含脂滴，呈椭圆形气球样，有的斑块中可见显著的平滑肌细胞增生及大量的弹力纤维形成。

Results From the fourth week, in diabetic rats, the contents of AGEs in plasma and the abdominal aorta increased, the relative area of α-SM-actin in the abdominal aorta decreased, the density of nucleus of VSMC increased, and mitochondria and rough endoplasmic reticules in VSMC increased.

结果 从4周起，DM大鼠血浆和腹主动脉的AGEs显著增多；腹主动脉α-SM-肌动蛋白的相对面积减小，VSMC的细胞核密度增大，线粒体和粗面内质网增多。

In histopathology sections showed that alveoli were complete and clear with walls being thin and brittle. In experimental group, some petechia were observed in lung samples , the area of fibroblast and fibrinogen in histopathology sections were found , and the ground-glass predominance and reticulation structure in Micro-CT findings were increased during the period from the 1st week to the 3rd week, and degrade in the 4th week after the administration.

结果显示，控制组之肺脏检体色泽正常，没有出血，组织病理学则以I型肺泡细胞为主，无间质性肺炎且肺泡完整清净，肺泡壁薄而完整；实验组方面，第一~三周肺脏检体外观及组织病理的呈现出血点及出血病灶且越趋严重，第四周则消退，且Micro- CT影像评估亦相同。

Specimens of 8 gliomas were taken from the tumor, peritumoral oedematous region and adjacent cerebral tissue of each patient.

8例胶质瘤病例，标本分别取自同一病例的瘤体、瘤周水肿区和邻近脑组织。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。