周质

The liver fibrotic model was induced by CCl4 i.p for 5wk. Telmisartan was given at the same time model establishment in each intervened group by administration lasted for 6wk. Decollate to get the blood of all rats after 7 weeks . ALT、AST and ALB of serum was detected by automatic biochemistry equipment. Hyaluronic acid was detected by ELISA detection. Liver and spleen was obtained to calculate the index. The liver pathological changes were observed in each group of rats after HE staining to evaluate the therapeutic effect of Telmisartan; TGF-β1、PPAR-γand PDGF of liver tissue was detected by the method of immunohistochemistry respectively; The mRNA expression of TGF-β1、MMP-1、TIMP-1、α-SMA、PPAR-γand iNOS was detected by RT-PCR detection, respectively.

腹腔注射CCl4制备SD大鼠肝纤维化动物模型，连续灌胃6周，处死动物取血，检测血清ALT、AST、ALB；ELISA法测定血清透明质酸；取肝、睥，并计算肝、脾指数，组织切片HE染色后进行组织病理学疗效评估；用SP免疫组化法测定肝组织TGF-β1、PPAR-γ及PDGF蛋白表达；半定量RT-PCR方法检测肝组织TGF-β1、MMP-1、TIMP-1、α-SMA、PPAR-γ和iNOSmRNA的表达。

Affer 4 to 8 weeks, the serum n itric oxide, plasma endotheliolysin, cGMP and lipid peroxide were meas ured and morphologic change of renal tissue examined.

为探讨穿心莲API0134防治家兔系膜增殖性肾炎作用机理，采用高胆固醇饲料另加牛血清白蛋白一次性注射方法建立家兔M sPGN模型，观察4～8周，检测血清一氧化氮，血浆内皮素，环鸟苷酸（cGMP 脂质过氧化物以及肾组织形态学改变。

The profiles of the terminals are sometimes exhibited finger like projections. The X organ locates at the ventral surface of the medulla terminalis ganglion in the eyestalk, oppositing to SG.

神经末梢含有大量的膜结构包围的颗粒、线粒体、粗面内质网和许多电子透明的小泡，末梢外周有时可见指状突起。

In the first week of renal obstruction, the immunohistochemical labeling of tubular VEGF was intensified, accompanied by deformation and dilation of adjacent Flk-1-positive PTC lumina, mild renal tubular cell apoptosis and minimal tubulointerstitial fibrosis.

结果： 1。肾脏梗阻第一周，肾小管上皮细胞胞浆里的VEGF染色在局部有增强，Flk-1阳性PTC数量变化不显著，肾小管上皮细胞凋亡和肾间质纤维化很少见。

MSCs did not proliferate within the alginate-GRGDY matrix during the 2 weeks examined. These results were further substantiated by concurrent cell density measurements using a hemocytometer.

在2周的检查期内，间充质细胞干细胞在甘氨酸－精氨酸－甘氨酸－天冬氨酸－酪氨酸藻酸盐环境中并没有发生增殖，这些结果在用血细胞计数器测量细胞密度时得到进一步确认。

Heterochromatin is dynamically regulated during the cell cycle and in response to developmental signals.

在细胞周期中，异染色质会被进行动态的调节，以响应发育信号。

RESULTS: hMSC had good homogeneousness and immunological reaction after implantation.

结果： 第5代呈集落生长的hMSC，均一性好。hMSC可在脑内存活6周以上；随着时间的延长，hMSC在脑内迁移的范围越来越大；间接免疫荧光表明hMSC在大鼠脑内表达人神经元特异性烯醇化酶、神经丝蛋白和胶质纤维酸性蛋白；模型鼠的肢体运动功能有明显改善。

As a result penicillium of Ma Erni humble is double photograph bacterium, mould bacterium colony can discover the broom shape mycelial of diagnostic sex,; of pigment of rose of water-solubility of the generation after sanded Paul fosters 3 days is medullary inside and outside of cell of blood of the week outside mixing all can discover spore;PAS coloring sees bacterium body show circle, elliptic or sausage shape, size is differ, it is 2~8 μ M about, color of afterbirth wall incarnadine and clear and successive, it is thus clear that inside the cell of sausage shape one apparent horizontal stroke is lain between, afterbirth is qualitative not easy and chromatic.

结果马尔尼菲青霉菌为双相菌，霉菌型菌落可发现特征性的扫帚状菌丝，沙保罗培养3天后产生水溶性玫瑰色素；骨髓和外周血细胞内外均可发现孢子；PAS染色可见菌体呈圆形、椭圆形或腊肠状，大小不一，约为2~8μm，胞壁染红色且清楚连续，在腊肠状的细胞内可见一明显的横隔，胞质不易着色。

Results: Expression of PAI-1, TIMP-1 and FN in kidney of diabetic rats began to increase in the second week of diabetes; PAI-1 and TIMP-1 mainly expressed in intracytoplasm of renal tubular epithelial cells, while FN mainly expressed in renal tubule matrix and glomerului; Their expression showed a tendency of increasing along with the progression of diabetes.

结果：PAI-1、TIMP-1及FN表达从糖尿病2周起较正常对照组明显增多(P.01)，PAI-1和TIMP-1阳性表达主要位于肾小管上皮细胞胞浆内，FN阳性表达主要位于肾小管间质和肾小球，且随着糖尿病进展有逐渐增加的趋势。

Different concentrations of indomethacin were added into ten glioma cell cultures and the levels were detected after one week.

对10例胶质瘤细胞培养液中加入不同浓度消炎痛溶液，培养1周后测其上清液PGE2的含量。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。