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The data were divided into four groups,A group included 57 cycles:a proximal tubal ligation with distal tubal salingostomy had been introduced to the patients before the IVF.B group included 55 cycles,a salpingectomy had been introduced to the patients before the IVF.C group included 52 cycles:no surgical procedure was adopted before IVF-ET.The control group was defined as D group and included 78 cycles of IVF-ET.

回顾性分析2007年3月至2009年3月在沈阳204医院生殖中心因输卵管性不孕接受IVF-ET 治疗共242周期的临床资料,根据IVF-ET前输卵管情况分4组,A组:57个周期,采用输卵管近端结扎伞端造口术;B组:55个周期,已行输卵管切除术;C组:52个周期,积水未行手术组;D组:78个周期,单纯输卵管阻塞,作为对照组。

In this paper, total logistics amounts are chosen as evaluation index, and artificial time series are designed to solve the shortness of statistical data in Chinese logistics. Spectrum estimation theory depicts time characteristics in frequency domain thus has such benefit than time domain methods. This paper evaluates the period of Chinese logistics using spectrum estimation. Stationarity of artificial series is verified, parameter sensitivity of truncation point is analyzed, six periods with different delay window are compared, and significance of period evaluated is tested.

中国物流统计数据缺乏,客观上限制了对其周期规律的研究,本文选取社会物流总额作为测度指标,设计了一种人工序列,解决了统计数据过短问题;谱估计法从频域角度揭示客观事物的时间特性,在研究时间序列周期波动方面具有时域分析法所不具备的优势,作者采用谱估计法对中国物流发展周期进行测定,检验了指标序列平稳性,分析了截断点参数灵敏度,比较了6种不同滞后窗下周期值,并检验了所测得周期的显著性。

Methods The data of 242 cycles of IVF-ET which were accomplished in the Reproductive Medicine Center of 204 hospital during March 2007 and March 2009 with a history of hydrosalpinx were analyzed retrospectively.The data were divided into four groups,A group included 57 cycles:a proximal tubal ligation with distal tubal salingostomy had been introduced to the patients before the IVF.

回顾性分析2007年3月至2009年3月在沈阳204医院生殖中心因输卵管性不孕接受IVF-ET治疗共242周期的临床资料,根据IVF-ET前输卵管情况分4组,A组:57个周期,采用输卵管近端结扎伞端造口术;B组:55个周期,已行输卵管切除术;C组:52个周期,积水未行手术组;D组:78个周期,单纯输卵管阻塞,作为对照组。

It analyses the essential factors, structure, environment as well as functions of high-tech corporation system and compares the similarities and differences between high-tech corporation system and traditional corporation system; it analyses characteristics in each stage of high-tech corporation lifecycle as well as management roots which lead to the declination of high-tech corporation and researches into the similarities and differences between high-tech corporation lifecycle and other lifecycles, including traditional corporation lifecycle, industry lifecycle, product lifecycle and ecology lifecycle; it studies functional coupling in each stage of high-tech corporation lifecycle and puts forward ways to realize internal coupling of high-tech corporation system and external environment coupling; based on fundamental concepts of dissipative structure, it summarizes six inherent laws of system evolution and on the basis of those laws it advances six principles of high-tech corporation lifecycle management, it poses four sequential parameters of high-tech corporation system, analyses coordination and competition between them and then it advanced four principles of high-tech corporation management; it researches into various cycles in high-tech corporation and puts forward five measures of high-tech corporation management from the point of hypercycle theory; it studies the relations between carious innovation of high-tech corporation innovation system and sets up models of innovation motive forces and resistances, after that it analyses the alternation laws of innovation motive forces and resistances in each stage of high-tech corporation lifecycle, puts forward some measures to strengthen motive forces and lessen resistances and then from the angle of dissipative structure theory, it researches into relevant questions of high-tech corporation innovation management; it studies the location, identification, cultivation, cultivation and protection of high-tech corporation core competence and researches into the key elements of core competence management in each stage of lifecycle and then from the angle of synergetic, it discusses several questions of high-tech corporation core competence management; it studies seven common characteristics of successful high-tech corporation culture and puts forward the ways and measures to cultivate and innovate high-tech corporation culture after that it researches into the characteristics of corporation culture in each stage of lifecycle and discusses relevant questions of high-tech corporation culture management from the point of hypercycle theory; it studies interplay of high-tech corporation system and environment and researches into the development and management of high-tech corporation ecology system after that it analyses the construction and disintegration of high-tech corporation strategic alliance.

剖析了高新技术企业系统的要素、结构、环境与功能,比较了高新技术企业系统与一般企业系统的异同;剖析了高新技术企业在生命周期各阶段的特点及衰退的管理根源,探讨了高新技术企业生命周期与一般企业生命周期、产业生命周期,产品生命周期和生物生命周期的异同;研究了高新技术企业生命周期各阶段的功能耦合,提出了实现高新技术企业系统内部耦合及系统与外部环境耦合的途径;以耗散结构理论的基本概念为基础,总结归纳出系统演化的六大内在规律,据此提出了高新技术企业生命周期管理的六个原则;提出了高新技术企业系统的四个序参量,剖析了生命周期各阶段序参量的协同与竞争,进而提出了高新技术企业管理的四大原则;研究了高新技术企业中的各种循环,从超循环理论的角度提出了高新技术企业管理的五大措施;研究了高新技术企业创新系统中各种创新的关系,建立了创新动力和创新阻力模型,剖析了生命周期各阶段创新动力与阻力的变化规律,提出了增强创新动力与减小创新阻力的措施,从耗散结构理论的角度研究了高新技术企业创新管理的相关问题;研究了高新技术企业核心竞争力的定位、识别、培养及保护,剖析了生命周期各阶段核心竞争力管理的要点,从协同理论的角度研究了高新技术企业的核心竞争力管理的几个问题;剖析了成功的高新技术企业文化的七个共同特点,提出了培养和创新高新技术企业文化的途径及措施,研究了生命周期各阶段企业文化的特征,从超循环理论的角度探讨了高新技术企业文化管理的相关问题;研究了高新技术企业系统与环境的交互作用,探讨了高新技术企业生态系统的开拓与管理,剖析了高新技术企业战略联盟的组建与解体。

Itanalyses the essential factors, structure, environment as well as functions of high-techcorporation system and compares the similarities and differences between high-tech corporationsystem and traditional corporation system; it analyses characteristics in each stage of-high-techcorporation lifecycle as well as management roots which lead to the declination of high-techcorporation and researches into the similarities and differences between high-tech corporationlifecycle and other lifecycles, including traditional corporation lifecycle, industry lifecycle,product lifecycle and ecology lifecycle; it studies functional coupling in each stage of high-techcorporation lifecycle and puts forward ways to realize internal coupling of high-tech corporationsystem and external environment coupling; based on fundamental concepts of dissipativestructure, it summarizes six inherent laws of system evolution and on the basis of those laws itadvances six principles of high-tech corporation lifecycle management; it poses four sequentialparameters of high-tech corporation system, analyses coordinfition and competition between themand then it advanced four principles of high-tech corporation management; it researches intovarious cycles in high-tech corporation and puts forward five measures of high-tech corporationmanagement from the point of hypercycle theory; it studies the relations between cariousinnovation of high-tech corporation innovation system and sets up models of innovation motiveforces and resistances, after that it analyses the alternation laws of innovation motive forces andresistances in each stage of high-tech corporation lifecycle, puts forward some measures tostrengthen motive forces and lessen resistances and then from the angle of dissipative structuretheory, it researches into relevant questions of high-tech corporation innovation management; itstudies the location, identification, cultivation, cultivation and protection of high-tech corporationcore competence and researches into the key elements of core competence management in eachstage of lifecycle and then from the angle of synergetic, it discusses several questions ofhigh-tech corporation core competence management; it studies seven common characteristics ofsuccessful high-tech corporation culture and puts forward the ways and measures to cultivate andinnovate high-tech corporation culture after that it researches into the characteristics ofcorporation culture in each stage of lifecycle and discusses relevant questions of high-techcorporation culture management from the point of hypercycle theory;' it studies interplay ofhigh-tech corporation system and environment and researches into the development andmanagement of high-tech corporation ecology system after that it analyses the construction anddisintegration of high4ech corporation strategic alliance.

剖析了高新技术企业系统的要素、结构、环境与功能,比较了高新技术企业系统与一般企业系统的异同;剖析了高新技术企业在生命周期各阶段的特点及衰退的管理根源,探讨了高新技术企业生命周期与一般企业生命周期、产业生命周期,产品生命周期和生物生命周期的异同;研究了高新技术企业生命周期各阶段的功能耦合,提出了实现高新技术企业系统内部耦合及系统与外部环境耦合的途径:以耗散结构理论的基本概念为基础,总结归纳出系统演化的六大内在规律,据此提出了高新技术企业生命周期管理的六个原则;提出了高新技术企业系统的四个序参量,剖析了生命周期各阶段序参量的协同与竞争,进而提出了高新技术企业管理的四大原则;研究了高新技术企业中的各种循环,从超循环理论的角度提出了高新技术企业管理的五大措施;研究了高新技术企业创新系统中各种创新的关系,建立了创新动力和创新阻力模型,剖析了生命周期各阶段创新动力与阻力的变化规律,提出了增强创新动力与减小创新阻力的措施,从耗散结构理论的角度研究了高新技术企业创新管理的相关问题;研究了高新技术企业核心竞争力的定位、识别、培养及保护,剖析了生命周期各阶段核心竞争力管理的要点,从协同理论的角度研究了高新技术企业的核心竞争力管理的几个问题;剖析了成功的高新技术企业文化的七个共同特点,提出了培养和创新高新技术企业文化的途径及措施,研究了生命周期各阶段企业文化的特征,从超循环理论的角度探讨了高新技术企业文化管理的相关问题;研究了高新技术企业系统与环境的交互作用,探讨了高新技术企业生态系统的开拓与管理,剖析了高新技术企业战略联盟的组建与解体。

The invention relates to a method for synchronizing at least one node of a bus system, which is operated with a predeterminable system clock period, whereby a local clock period and a reference clock period are given for the at least one node, and the reference clock period is synchronized with the system clock period. A local clock period, which is synchronized with the system clock period, of the at least one node is produced whereby linking the local clock period with a splitting factor, whereby the splitting factor represents a ratio of the reference clock period to the local clock period. The splitting factor for synchronizing the local clock period with the system clock period is adapted by adding or subtracting a adaptation value.

用于同步至少一个总线用户的方法,所述的总线系统用可预定的系统周期运行,由此为该至少一个用户给定局域时钟脉冲周期和基准时钟脉冲周期并且把局域时钟脉冲周期与系统时钟脉冲周期同步,其中通过把局域时钟脉冲周期与分配系数相关联的方式产生同步到系统时钟脉冲周期的、至少一个用户的局域时钟脉冲周期,其中,分配系数说明基准时钟脉冲周期与局域时钟脉冲周期的比例,其特征在于,通过加或者减一个适配值或者说补偿值,对用于把局域时钟脉冲周期与系统周期同步的分配系数进行匹配。

The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法,研究丘脑网状核(nucleus reticularis thalami,RT)中γ-氨基丁酸(gamma-amino butyric acid ,GABA)能神经元、一氧化氮(nitrogen monoxidum,NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate,cAMP)及中缝背核(nucleus raphes dorsalis,DRN)至RT的5-羟色胺(5-hydroxytryptamine,5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP,5μg),注射当天睡眠时间略有减少,第二日睡眠时间显著减少,觉醒时间明显增多,第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后,与生理盐水组比较,睡眠时间增加,觉醒时间减少;而RT内微量注射L-谷氨酸(glutamic acid, L-Glu, 0.2μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline,BIC,1.0μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen,BAC,1.0μg)后,产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg,0.5μg)后,与生理盐水组对比,睡眠时间略有减少,但无显著性意义;而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside,SNP,0.2μg)后可明显增加觉醒时间,缩短睡眠时间;微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine,L-NNA,2.0μg)后,引起睡眠时间增多,觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用;RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后,与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠,其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate,MOR,1.0μg)后与生理盐水组对比,睡眠时间减少而觉醒时间增加; RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride,NAL,1.0μg)后与生理盐水组比较,睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后,与生理盐水组对比,原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较,睡眠时间增多而觉醒时间减少;RT内微量注射亚甲蓝(methylene blue,MB,1.0μg)后,与NS组比较,睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 0.2μg)比较,睡眠时间减少,觉醒时间增多;大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射二甲基麦角新碱(methysergide, MS, 1.0μg )后,与对照组(DRN注射L-Glu 0.2μg,双侧RT注射NS 1.0μg)比较,睡眠时间增多,觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine,PCPA,10μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 1.0μg)比较,睡眠时间增多,觉醒时间减少;大鼠DRN内微量注射PCPA(10μg),产生睡眠增多效应后,在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan , 5-HTP, 1.0μg )后,与对照组(DRN注射PCPA 10μg,双侧RT注射NS 1.0μg)比较,睡眠时间减少,觉醒时间增多。

We performed a simulative test, which confirms that wavelet analysis can separate annual wobble and Chandler wobble. Our results show that this method can be used in astronomical geodynamies effectively. This paper is divided into two parts. The first is about statistic characteristic of polar motion. Polar motion includes secular motion, long period fluctuations, Chandler wobble, annual wobble and high frequency wobble. The secular motion is 3.4mas/year and towards 760W meridian. Long period fluctuations have difference periods in x-axis and y-axis. They are 31.7-year and 24-year in x-axis and 28.5-year and 22.9-year in y-axis. These 2~? decades fluctuations have an amplitude of about 30 mas , and are very nearly linearly polarized, with the observed motion of pole being almost entirely along a line between 360E and 1440W. There is a 55.4-year wobble whose amplitude is 9 mas. The amplitude of the interannual fluctuations is about 4? mas. The amplitude of long period fluctuations decreased after 1970. The annual wobble is a steady wobble. It retrograde wobble is only 1/20 of prograde wobble in amplitude.

本文的工作主要分为两部分:第一部分是通过分析POLE97序列,我们对极移的统计特性有了一个较全面的认识,极移主要包括趋势项、长周期项、Chandler项、周年项和高频项:趋势项的方向是西经76°,速度为每年3.4mas;长周期项中Markowitz 项在X、Y两个方向有不同的周期,它们分别是:X方向的两个周期是31.7年和24 年,Y方向的两个周期为28.5年和22.9年它们叠加在一起是一个线偏振运动,最大振幅约为30mas,偏振方向在西经144°和东经36°之间;极移的长周期波动中还存在一个 55.4年周期的圆周运动,振幅约为9mas;十年尺度变化的振幅在4~6mas之间,在Y 方向十年尺度的成份比较多,它们的周期在X方向和Y方向不是对应的;从七十年代年开始长周期变化的振幅明显降低;周年项是一个振幅稳定的摆动,在X、Y两个方向的振幅略有差别,逆向运动振幅大约为顺向运动振幅的1/20;Chandler摆动的振幅自1900年以来经历了几次较大的变化,其中包括1915年和1955年两次极大值,振幅分别达到0&。25和0&。28,以及1925~1940期间小于0.09的过程,Chandler项在X、Y 两个方向的振幅几乎完全相等,其逆向运动振幅不到顺向运动振幅的1/50。

Of, the structural periodicity (the number of base pairs per turn of the double helix).

酶切周期与结构周期相符,酶切周期确定是结构周期的一种反映。

Based on the return map and the principle of closed vectors, a new method is proposed to extract unstable periodic orbits embedded in chaotic attractors. As examples, the UPOs embedded in chaotic attractors of Logistic, Hénon and Lorenz are extracted respectively by this method. And our results of Skewed Hénon map also be compared with Nusse's. These results suggest that this method is valid for unstable periodic orbits from period one to period infinite of arbitrary dimension chaotic system. The dynamic considerations of spiking and UPO coding for individual neuron and neural system under external periodic and chaotic exciting stimulus also be studied in this dissertation. A lot of spiking phenomena, such as synchronization, period, and chaos appear alternatively with the changing of the stimulus frequency. For the small stimulus frequency the neuron could completely convey the periodic signal in synchronous anti-phase into interspike intervals sequences. For the slow time–scale chaotic input, the output two ISI sequences are reciprocally related to input signals, and their oscillation wave shape in time course can be derived from that of the input signals variation, furthermore, the similar input sequence and order of UPOs, distribution of LES and value of KYD remain in attractors reconstructed from ISI sequences.

发现周期信号在单个神经元传递过程中,随着激励频率的改变,神经元输出的峰峰间期interspike interval时间序列呈现出周期、混沌和准周期的交错变化,特别当外加激励信号频率较低时,周期信号可以通过神经元ISI序列以反相同步的周期运动形式传递下去;同时无论是周期还是混沌激励信号,在神经系统中的传递均与其自身强度和神经元之间的耦合强度的大小密切相关;快变时间尺度的混沌激励信号在耦合的神经系统传递过程中,会造成大量基本信息的丢失;而慢变时间尺度的混沌激励信号在神经系统传递中,它的非线性特征信息,如混沌吸引子、不稳定周期轨道、Lyapunov指数谱和分形维数,会通过系统输出的ISI序列部分地重现出来,如与输入慢变时间尺度的混沌激励信号相比,神经系统输出的ISI序列具有:相似几何形状的混沌吸引子、相近的Lyapunov指数谱和分形维数、局部结构相同的不稳定周期轨道的排列方式。

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在对危险的南部地区访问时,他斥责什叶派民兵领导人对中央集权的挑衅行为。

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