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This study was designed to investigate the mechanisms of histone deacetylase inhibitors (sulfonamide anilide compound referred as the Compound') with antitumor activity against human bladder cancer cells. MATERIALS AND METHODS: Treated with different concentrations of the Compound and HCPT for different periods of time, human bladder cancer cell line BIU-87 growthwas measured by MTT assay.

材料与方法:以不同浓度的Compound和羟基喜树碱作用于体外培养的膀胱癌BIU-87细胞株;采用MTT法检测细胞生长抑制率;以流式细胞术测定不同浓度的Compound和HCPT作用前后膀胱癌细胞的调亡情况及细胞周期的变化;应用RT-PCR分析Compound和HCPT作用前后膀胱癌细胞中P21(上标 waf/cif1)mRNA表达的变化。

The analysis of the continuous property of raw silk size Setting the decaying rate^and the quasi-cycle value T in the model of the silk size autocorrelation coefficient, building the time series of a single cocoon reeling silk size with autoregressive model, then by combining k such time series according to different phrase, obtained time series of the raw silk size, and finally count up the silk size deviation of the time series.

k粒缀生丝纤度连续性特征解析设定生丝纤度自相关系数模型中衰减率A与拟似周期T的值,用自回归预测模型生成一粒缨生丝纤度时间序列,然后将k个这样的序列以不同位相并合得到卜粒缥生丝纤度序列,统计该序列的生丝纤度偏差。

Using 24 heads of beeves to conduct the test of effect of different raising and managing ways on beeves liveweight gain in Danzhai County, Guizhou Province during September and December, 1995, and analysing the fodder conversion efficiency, liveweight gain efficiency and economic benefit of beeves, the results showed that the fattening effect was significant while under the condition of fully confined rearing ammonifying fodder combined with little concentrated feeding stuff and semi-confined rearing combin...

1995年9月~12月在贵州省丹寨县,用24头试验牛进行了不同饲养管理方式对肉牛增重效果的试验,并对肉牛的饲料转化率和增重率以及经济效益进行了分析,试验结果表明:全舍饲氨化秸秆结合少量精料组与半舍饲结合放牧组育肥效果显著,经济效益最好。但是,在我国贫困地区,适合推广的仍然是全放牧育肥法,尽管该方式延长了饲养周期,但在我国目前的情况下,仍然是经济的

The colony forming and the cell cycle were analyzed with flow cytometry, and the mRNA expression of bcl-2, c-myc gene were determined with RT-PCR method. Results Resveratrol could markedly inhibit proliferation of human gastric cancer cells compared with that of the blank control group. The cell cycle was blocked to G0/G1. The mRNA level of bcl-2 and c-myc gene were decreased compared with that of the blank control group.

结果 白藜芦醇可抑制胃癌细胞增殖和集落形成能力,低、高剂量组的抑制率分别为6.9%,17.6%和27.98%,63.39%,差异均有统计学意义(P.05);白藜芦醇能使胃癌细胞周期阻滞于G0/G1期,明显下调胃癌细胞bcl-2、c-myc基因mRNA表达水平(P.05);用药24 h后,白藜芦醇高剂量组bcl-2和c-myc基因相对表达量分别为(0.54±0.04),(0.58±0.05),与空白对照组(0.91±0.05),(0.85±0.03)比较,差异均有统计学意义(P.05)。

It was also found that the backwashing of carbonate gravel BAF and up-flow BAF were more difficult than that of ceramist and down-flow BAF respectively.

碎石填料床的空隙率高于陶粒填料床,因而具有较长的运行周期,但比陶粒滤池更难反冲洗。

Based on a series of analysis for the relevant data during the period of 1950~1989, the relationship between the ozone layer variation/solar activity and the periodically prevalent features of two kinds of human infectious diseases in China, the epidemic cerebrospinal meningitis and human plagueepisodes, is presented and analyzed for the first time in this paper.

通过对1950~1989年间一系列有关资料进行分析,首次研究和报道了臭氧层变化、太阳活动与流行性脑脊髓膜炎及鼠疫传染病性病率流行周期特徵之间的关系。

The application in billet tension straightening machine and transmission chain has shown that the gear lifetime is prolonged from the original 60~90 days to 150~180 days, the equipment utilization rate is also increased.

在方坯拉矫机和传动链条上应用表明,轴承在线使用周期由原来的60~90天延长到150~180天,提高了设备的作业率。

According to the results of comparison between these methods of spectrum evaluation, a new method of power spectrum evaluation of welding arc sound is advanced by means of association of wavelet packet analysis with the Welch average method .

对试验系统采集到的焊接电弧声进行了小波包多层分解,并利用周期图法、Welch 平均法及AR模型法,对各频段信号进行功率谱估计。根据不同谱估计方法的对比结果,提出小波包分解结合Welch 平均法对焊接电弧声进行功率谱估计的新方法。通过对几种规范与飞溅率下的电弧声功率谱的初步分析,发现其功率谱分布具有一定的规律性,并且不同频段谱峰值及其对应频率与焊接飞溅具有相关

Milankovitch orbit cycle consists of eccentricity, inclination and procession of equinoxes, which lead to palaeoclimatical cyclic transformation and form high frequency sequence, parasequence and beds with cyclic time of ten, four and two thousand years respectively.

米兰柯维奇天文旋回包括偏心率旋回、倾斜率旋回和岁差旋回,这几个轨道参数所驱动的古气候变迁,分别形成了周期为10万年(或40万年)、4万年及2万年的高频层序,即小层序组、小层序及小层单元。

It is concluded that the method not only improves on-time delivery, but reduces cycle time also.

进一步的仿真验证也说明了该调度优化方法能在提高订单准时交货率的同时缩短生产周期时间。

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