周

RESULTS: The defects of articular cartilage were repaired with osteofibrous tissue in group C and B.

术后1、2、4、8、12周处死实验动物，D组动物和手术组于术后1周和12周同时处死。

Methods Outbred stock ICR and inbred B6 female mice (3 weeks of age) were fed HFD, HFD-fructose and standard rodent chow, respectively. After exposure to the diets for 6 weeks, HFD and HFDF groups were injected intraperitoneally with STZ, and controls were injected with vehicle,then kept on the same diet for the next 6 weeks.

分别以高脂饲料、高脂饲料－果糖饮水和常规饲料喂养3周龄的封闭群ICR和近交系C57BL/6J(B6)小鼠6周后，HFD和HFDF组腹腔注射STZ，对照组注射相应体积柠檬酸钠溶液，然后分别以相应饲料继续喂养6周。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

The results showed that leaf epidermal cells were polygonous or irregular in shape. Stomatal complexes only present on abaxial epidermis and the stomata was paracytic type. There were five types of anticlinal walls of abaxial and adaxial cells (straight, rounded, undulated, sinuous, straight-curved). Trichomes on abaxial epidermis exist or not. Ornamention types of periclinal walls could be divided into punctuate, smooth and striate. Ornamention of periclinal walls on inner side of abaxial epidermal cells varied widely (irregular, smooth, roughly reticular, micro hairy, granular, scaly).

结果表明：润楠属植物叶表皮细胞形状为多边形或不规则形，气孔复合体均为平列型且仅分布在下表皮；上下表皮细胞的垂周壁式样有5种类型：平直、圆滑、技波、波状、平直－弓形；下表皮毛被有或无；上表皮平周壁纹饰类型有：点状、平滑、条纹；下表皮内面平周壁纹饰类型有：不规则、平滑、粗糙网状、微毛状、颗粒状、鳞片状。

The results showed that leaf epidermal cells were polygonous or irregular in shape. Stomatal complexes only present on abaxial epidermis and the stomata was paracytic type. There were five types of anticlinal walls of abaxial and adaxial cells (straight, rounded, undulated, sinuous, straight-curved). Trichomes on abaxial epidermis exist or not. Ornamention types of periclinal walls could be divided into punctuate, smooth and striate. Ornamention of periclinal walls on inner side of abaxial epidermal cells varied widely (irregular, smooth, roughly reticular, micro hairy, granular, scaly).

结果表明：润楠属植物叶表皮细胞形状为多边形或不规则形，气孔复合体均为平列型且仅分布在下表皮；上下表皮细胞的垂周壁式样有5种类型：平直、圆滑、浅波、波状、平直-弓形；下表皮毛被有或无；上表皮平周壁纹饰类型有：点状、平滑、条纹；下表皮内面平周壁纹饰类型有：不规则、平滑、粗糙网状、微毛状、颗粒状、鳞片状。

Clinical pathology showed liver, spleen and kidney of coinfection chickens swelled from 2 to 4 week. Perihepatitis and pericarditis could be seen. Coinfection chickens, REV chickens and MDV chickens could be seen tumor on liver, spleen, kidney and heart at 5, 6, 6 week.

大体病变结果显示，混合感染组2～4周肝、脾、肾稍肿大，并有肝周炎、心包炎等，混合感染组、攻REV组和攻MDV组分别在5、6、6周时肝、脾、肾、心脏呈不同程度的肿大，有大小不等肿瘤结节。

Results: The male patients appeared more than females in spinal cord AVMs, but the occult intramedullary AVMs had the same morbidity The patients with intramedullary AVMs and perimdeullary AVF were younger, in contrast, patients with dural AVF were usually older than 40 years of age. The intra - medullary AVMs were most common located in the cervical and thracic - lumbar spinal cord, the perimedullary AVF and dural AVF were most seen in the low thracic of lumbar region. The most common initial symptom associated with intramedullary lesions was accute onset where as the progressive aggravation was the most common presenting symptom in cases of dural AVF. The prognosis of the patients with intramedullary lesions had hemorrhage was worse than who without hemorrhage.

结果：脊髓AVM s中，隐匿型AVMs无明显的性别差异，余各类型男性均多于女性；髓内AVMs、髓周AVF以青少年多见，硬膜型AVF发生于中老年；髓内AVMs多见于颈髓及胸腰段脊髓，髓周AVF及硬膜型AVF多见于胸腰段；髓内AVMs以急性起病多见，髓周AVF表现为进行性加重，少数可急性发作，硬膜型AVF以慢性起病多见；髓内出血者预后较无出血者差。

Results Of the 21 patients, 5 showed transplanted kidney swelling alone, 8 showed transplanted kidney swelling and perinephric dropsy, 1 showed atrophy and function failure of both kidney, 2 showed perinephric hemorrhage, 1 showed multiple small cysts, small calculi and perinephric dropsy of transplanted kidney, 1 showed ureteral fistula, ureteral stricture, hydronephrosis and infarct of subsegment kidney, 1 showed hydronephrosis and ureteral calculi, 1 showed swelling and pyonephrosis, and 1 showed rupture of transplanted kidney.

结果 21例患者中5例仅表现为移植肾肿胀，8例表现为移植肾肿胀并肾周积液；1例为双肾萎缩伴功能丧失；2例表现为移植肾周积血；1例表现为移植肾多发小囊肿、小结石并肾周积液；1例表现为移植肾输尿管旁尿瘘伴输尿管狭窄及肾积水、亚段肾梗死；1例表现为移植肾积水并输尿管结石；1例表现为移植肾肿胀，肾盂内积脓；1例表现为移植肾破裂。

Objective: To describe the anatomy of the superior and inferior aspect of the perirenal space as well as the renal fascia with CT radiography in vivo.

目的：通过对正常成人活体肾周间隙和肾筋膜的多层螺旋CT及三维重建图像的观察和测量分析，探讨肾筋膜的附着、肾周间隙的纵向通连情况等相关指标，以及多层螺旋CT对肾周间隙通连研究的诊断价值。

Combination of clinical diagnosis of pritonsillar abscess with needle aspiration of pus is suitable to clinical pratice. Needle aspiration and incision drainage of pus together with appropriate antibiotic therapy are the optimal treatment for peritonsillar abscessor and antibiotic therapy is suitable for peritonsillits.

临床诊断配合穿刺抽脓对扁周脓肿进行诊断能满足临床实践的需要，穿刺抽脓、切开排脓配合适当抗生素治疗扁周脓肿或单纯抗生素治疗扁周炎是最适当的治疗方法，完成治疗疗程对获得最佳疗效具有重要意义。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。