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The Reformation triggered a religious war, and Bodin\'s idea of legitimacy was mixed without certain conclusion, the struggle of concept became a cause of war. Hobbes pondered thoroughly to the conflict and war, and launched in two aspects about the thought of "recht": on the one hand, he criticized vigorously some controversial religious doctrines and ideas of good that was labeled dark kingdom, only left the teaching of "Jesus is Christ" which could be acknowledged commonly, at the same time absorbed Bodin\'s concept of "sovereignty", constructed a mortal God in the world—Leviathan; On the other hand, in order to make this mortal God to lay in a stable foundation, Hobbes constructed natural rights theory.

新教改革引发了宗教战争,博丹的合法性主张是混杂而无定论的,观念之争因而成为战争的一个根源,霍布斯对冲突和战争以及法权秩序的变化进行了深入思考,从两个方面展开了关于法权秩序的主张:一方面他将一些引起争议的教义、善的观念贬斥为黑暗王国的东西,大力批判,而只留下争论各方都能够承认的"耶稣就是基督"这一共识性的教义,同时又吸收博丹的主权概念,构造出尘世的上帝——利维坦;另一方面,为了使这一人间上帝奠立于稳固的基础上,霍布斯用政治科学构造了自然权利理论。

Its IR spectrogram performed by potassium bromide showed characteristic absorption peaks in the wavelength of 2917, 2849, 1716, 1463, 1382 and 720cm~(-1), respectively.

EZR_(2002)外观为黄色或黄绿色粉末,熔点在74~79℃之间;经溴化钾压片后的红外光谱图显示在2917、2849、1716、1463、1382和720cm~(-1)处有特征性吸收峰;溶于二氯甲烷后的紫外光谱图显示在412nm处有强吸收,在665nm处有次强吸收,还分别在505、535和605nm附近有弱吸收。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周,炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节,另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg,20分钟后踝关节照光,激光波长627.sum,功率密度 100mwcm',照射时间1000秒,能量密度100)/。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径,治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后,治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗,随机治疗一侧膝关节,另一侧作自身对照。兔耳静脉注入I'arrainrelomg/Kg,20分钟后,膝关节用金蒸气激光照射,激光能量密度100)儿旷。24 /J'时后取膝关节滑膜作病理检查,并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果: 1。模型观察:CIA大鼠炎症高峰期滑膜下炎细胞浸润明显,滑膜细胞明显增殖,炎症达到高峰后二周,血管缀形成,并侵蚀和破坏软骨和骨, CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生,滑膜下炎细胞浸润,也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明,各组织对HMME 的吸收速度和吸收量不同,荧光值一时间曲线不同,滑膜组织比皮肤和软骨对 HMME的吸收多,在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明:PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性,但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好,统计学检验差异有显著性。。3_军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少,图像分析结果表明面密度(阳性染色的面积总和与统计视野面积的比值)治疗组小于对照组,统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多,图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组,统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小,与对照组相比,统计学检验差异有显著性。结论:二。CIA、AIA的病理改变类似人类RA,可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同,滑膜组织比皮。

The absorption spectrum center wavelength of dolomite is near 232 μm is shorter than 235 μm of limestone,and thus RBD7 and RBD8 can be employed effectively to identify dolomite and limestone,respectively. Felsic rocks show AlOH and Fe3+ absorption characteristics in the VNIRSWIR region,while the maficultramafic rocks show Fe2+ and Fe,MgOH absorption features,hence the use of different valence state of iron and secondary minerals can distinguish them:ASTER band2/band1 represent Fe3+ distribution,ASTER band2/band1 represent the Fe2+ distribution,RBD6 can estimate the AlOH mineral abundance. Psammitic/pelitic schist containing phengite,chlorite,stilpnomelane,as well as the weathered surface covered by clay minerals,exist characteristic absorption spectrum in the 221 μm(band 6),and has a high reflectance in 165 μm(band 4),while the blueschist/greenschist show high reflectance in the 221 μm(band 6),and it exit low reflectance in 165 μm(band 4),and blueschist/greenschist appear low ASTER band4/band6 ratio.

白云岩的CO2-3吸收谱带中心波长位于232〖KG*3〗μm,与灰岩的CO2-3 吸收谱带中心波长位置235 μm相比,具有向短波长方向移动的特点,据此可以利用RBD7、RBD8分别有效的识别白云岩和灰岩;长英质岩石显示AlOH和Fe3+ VNIRSWIR吸收特征,而基性超基性岩石显示Fe2+和Fe、MgOH特征,利用不同的铁价态和次要矿物可以区分它们:ASTER band2/band1代表了含Fe3+矿物分布信息、ASTER band5/band4代表了含Fe2+矿物分布信息、RBD6可以估计AlOH矿物的丰度;砂质/泥质片岩含较多的多硅白云母、绿泥石、黑硬绿泥石以及风化后表面覆盖的其它粘土矿物,在221 μm(band 6)存在有特征的吸收谱带,并且在165 μm(band 4)具有较高的反射率,而蓝片/绿片岩在221 μm(band 6)反射率较高,不具有明显特征吸收谱带,同时其在165 μm(band 4)反射率较低,因此蓝片/绿片岩ASTER band4/band6 比值低。

The concentrations and pH values of scopoletin solution had no distinctive effect on the absorption kinetics. The absorption of scopoletin was a first-order process with passive diffusion mechanism. Scopoletin was well absorbed at stomachs and intestines in rats. Colon was the best absorption site of scopoletin, which suggest that a sustained-release preparation should be suitable for this compound.

不同质量浓度、pH对东莨菪素在大鼠全肠道的吸收没有显著性影响,药物的吸收呈一级动力学过程,吸收机制主要为被动扩散;东莨菪素在胃肠道均有较好的吸收,结肠为最佳吸收部位,提示适宜制成缓控释制剂。

Concentration of zingerone has no significant effect on its absorption kinetics. The best absorption segment of the intestine was duodenum, ileum, jejunum and colon by turns. The intestinal absorption of zingerone has the first-order kinetic characters with passive diffusion mechanism.

姜酮浓度对其K无显著性影响;姜酮的肠道最佳吸收部位为十二指肠;姜酮在大鼠肠道的吸收呈现一级吸收动力学特征且吸收机制为被动转运。

Itamin D from the skin and diet is metabolized in the lier to 25-hydroxyitamin D (Figure 1), which is used to determine a patient's itamin D status1,2,3,4; 25-hydroxyitamin D is metabolized in the kidneys by the enzyme 25-hydroxyitamin D-1-hydroxylase (CYP27B1) to its actie form, 1,25-dihydroxyitamin D.1,2,3,4 The renal production of 1,25-dihydroxyitamin D is tightly regulated by plasma parathyroid hormone leels and serum calcium and phosphorus leels.1,2,3,4 Fibroblast growth factor 23, secreted from the bone, causes the sodium–phosphate cotransporter to be internalized by the cells of the kidney and small intestine and also suppresses 1,25-dihydroxyitamin D synthesis.5 The efficiency of the absorption of renal calcium and of intestinal calcium and phosphorus is increased in the presence of 1,25-dihydroxyitamin D (Figure 1).2,3,6 It also induces the expression of the enzyme 25-hydroxyitamin D-24-hydroxylase (CYP24), which catabolizes both 25-hydroxyitamin D and 1,25-dihydroxyitamin D into biologically inactie, water-soluble calcitroic acid.2,3,4

从皮肤和食物来的维生素D在肝中代谢为25-羟基维生素D(图1),被用来决定病人体内维生素D情况的1,2,3,4;25-羟基维生素D在肾中被25-羟基维生素D1羟化酶(CYP27B1)转变为有活性的1,25-二羟基维生素D 。1,2,3,4由肾产生1,25-二羟基维生素D是被血浆甲状旁腺激素和血清钙,磷水平紧密调节。1,2,3,4由骨分泌的成纤维细胞生长因子23使钠磷协同转运蛋白被肾和小肠细胞内化及抑制1,25-二羟维生素D合成。5 在1,25-二羟基维生素D作用下肾和小肠吸收钙及磷的效率增高(图1)。2,3,6 它也包括25-羟四- 24 -羟化酶的表达(CYP24),且将1,25二羟基维生素D和25羟基维生素D异化成无生物活性,水溶性的维生素D3-23羧酸。2,3,4

In details, the strongest inhabitation to the shoot growth was observed when neutral soluble fractionates were supplied. The shoot biomass with neutral soluble fractionates added was decreased by 10.52% over the blank control, resulting in obvious increase of root: shoot ratio. It suggests that the root exudates would be self-poisonous. Besides, both acid and alkaline soluble fractionates exhibited the trend to increase the stem height and it is necessary to exploit the reasons.

在培养液中,分别加入分组的烤烟根系分泌物,均显著降低根系对NO_3~-、H_2PO_4~-、K~+离子的吸收和根系活力,推测根系分泌物中产生抑制作用的物质可作用在相当宽的pH范围;其中,碱溶性组分对H_2PO_4~-、酸溶性组分对K~+、中性组分对NO_3的吸收和根系活力的抑制作用较强,推测在烤烟根系分泌物中,可能存在多种抑制烤烟生K和养分吸收的化学物质;另外,抑制作用随着根系分泌物浓度的增加而增强。

The histamine in the particles will increase the transmission capacity of capillary and the velocity of the tissue-fluid flow and the superficial shear stress of related mast cell will be increased, which will once again activate mast cells to discharge active substance. Part of the active substance will be absorbed by capillary and the other part will be passed by tissue fluid to a remote place and it will activate the mast cells and the capillaries there. The directional path of the tissue fluid is approximately the same as the meridian, which forms the phenomenon of feeling-along-meridian on macroscale.

脱颗中的组胺等物质会引起毛细血管壁通透性的增加,进而引起组织液流动速度的增加和肥大细胞表面的切应力加大,这样会进一步促进肥大细胞的激活,从而释放更多的活性物质,这些物质一部分被静脉端毛细血管吸收进入血液,另一部分则随着组织液的定向流动向远处,并进一步刺激远处的毛细血管和肥大细胞,而组织液的定向流动途径和传统的经络线走向基本吻合,在宏观上就构成了循经感传现象。

The structures were studied by IR and NMR. The absorption frequencies of the carbonyl group markedly depended on the coordination no. of the tin atom. The chem. shifts of 119Sn and 13C and the 1J(119Sn-13Sn) coupling constants of the compounds were determine Small structural changes around the tin atom were reflected in the 119Sn chem. shifts. For tributyltin arylcarboxylates, a relationship between 119Sn chem. shifts and Hammett constants of the para-substituents was found. The biol. activities of same compounds have been studied. They may be used as fungicides for fruit.

通过对它们的红外光谱、核磁共振谱(^1^3C, ^1^1^9Sn)的研究,表明羰基红外吸收频率与锡原子的配位数有密切关系,同样分子上的微小变化明显地表现在δ119Sn上,对位取代基苯甲酸酯的δ119Sn与苯环上取代基的Hammett常数之间存在良好的线性关系:δ119Sn=19.11σ+110.612 n=7,γ=0.9955着重研究了部分化合物在经济作物上的抗病原菌能力,结果表明,这是一类具有广谱性的有机锡化合物,抗菌活性优于对比药剂朴海因,接近或相当于多菌灵,它们同时具有较强的除草活性。

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The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为:以确有疗效的中药复方为研究对象,以现代科学技术和传统中医药理论为技术支持,以该复方所治病证的药效响应为评价标准,以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。

I don't… don't know. He's unconscious.

我不……我不知道他休克了。