吸收因子

This study is to further investigate the mechanisms of osteoclastic bone resorption induced by IL-1 with established osteoclasts culture and osteoclasts, bone marrow stromal cells co-culture system.

本文利用建立的破骨细胞培养和破骨细胞、骨髓基质细胞共培养体系，在体外进一步研究IL-1诱导破骨细胞性骨吸收的机制，旨在探讨细胞因子在骨质疏松症骨丢失发生中的作用。

The stimulations of dexamethasone, lipopolysaccharide, erythromycin and hypertonic saline can significantly change the AQP1 expression in pleura, which indicate that AQP1 may contribute to the accumulation and clearance of pleuritic fluids. Aquaporin-1;Pleura;Pleural effusion;Dexamethasone;Lipopolysaceharide;Erythromycin;Hypertonic saline

地塞米松、内毒素、红霉素和高渗盐水刺激下胸膜组织AQP1表达的改变，提示存在炎症因子和渗透梯度下调控AQP1的途径，胸膜组织上AQP1可能参与了炎症性胸腔积液的分泌和吸收。

One of the potential advantages of the hypoxia-induced factor prolyl hydroxylase inhibitor approach to anemia therapy over ESA is improved regulation of iron absorption and iron recycling to improve the efficiency of iron utilization, partially via a mechanism of hepcidin suppression, to overcome functional iron deficiency.

用作贫血治疗的缺氧诱导因子脯氨酰羟基化酶抑制剂相对于红细胞生成作用刺激剂的一个优势是铁吸收和铁再利用的调节得到改善，提高了铁利用的效率，尤其是通过铁调节蛋白抑制机制，克服功能性铁缺乏。

Exchangeable sodium percentage of soil solution was selected as the sodic sless indicator according to the eltaractertsfics of the sodic soil.

根据苏打盐碱土的特殊性，采用土壤ESP作为胁迫指标因子，观察不同生育期水稻植株对Na、K的吸收、运输和分配，分析植株体内的离子响应及植物与盐碱作用关系。

A method is presented with which instantaneous PAR can be calculated with high accuracy from Moderate Resolution Imaging Spectroradiometer products and Digital Elevation Model.

该方法是对普通的大气传输模型进行简化，在模型中分别考虑了削减光合有效辐射的5个主要因子：瑞利散射、臭氧和水汽吸收、气溶胶散射以及地表和大气间的多次反射。

Soya bean cake is appled as the widest vegetal protein feedstuff at present time, but it includes a kind of anti-trophic factor of alpha-galactosis oligosaccharide such as raffinose、 stachyose、 verbascose etc, which affects absorbation and utilization of nutriments.

豆粕是目前应用最广泛的植物性蛋白饲料，但豆粕中含有一类α-半乳糖苷低聚糖抗营养因子，影响营养物质的吸收利用，如棉子糖，水苏糖等。

One of many factors contributory to development of periodontitis is an unerupted or abnormally erupted third molar and it may cause deep pocket formation and bony resorption at the distal side of adjacent second molar. It is also prone to result in periodontitis due to interdental food impaction and uneasy cleaning between the third molar and second molar.

在形成牙周炎的众多贡献因子中，其中因第三大臼齿萌发方向异常或萌发不全，可能造成第二大臼齿远心侧形成牙周囊袋和周围牙周骨头吸收；或第二及第三大臼齿间因缝隙口腔清洁不良而好犯牙周病。

Itamin D from the skin and diet is metabolized in the lier to 25-hydroxyitamin D (Figure 1), which is used to determine a patient's itamin D status1,2,3,4; 25-hydroxyitamin D is metabolized in the kidneys by the enzyme 25-hydroxyitamin D-1-hydroxylase (CYP27B1) to its actie form, 1,25-dihydroxyitamin D.1,2,3,4 The renal production of 1,25-dihydroxyitamin D is tightly regulated by plasma parathyroid hormone leels and serum calcium and phosphorus leels.1,2,3,4 Fibroblast growth factor 23, secreted from the bone, causes the sodium–phosphate cotransporter to be internalized by the cells of the kidney and small intestine and also suppresses 1,25-dihydroxyitamin D synthesis.5 The efficiency of the absorption of renal calcium and of intestinal calcium and phosphorus is increased in the presence of 1,25-dihydroxyitamin D (Figure 1).2,3,6 It also induces the expression of the enzyme 25-hydroxyitamin D-24-hydroxylase (CYP24), which catabolizes both 25-hydroxyitamin D and 1,25-dihydroxyitamin D into biologically inactie, water-soluble calcitroic acid.2,3,4

从皮肤和食物来的维生素D在肝中代谢为25-羟基维生素D（图1），被用来决定病人体内维生素D情况的1，2，3，4；25-羟基维生素D在肾中被25-羟基维生素D1羟化酶（CYP27B1）转变为有活性的1，25-二羟基维生素D 。1，2，3，4由肾产生1，25-二羟基维生素D是被血浆甲状旁腺激素和血清钙，磷水平紧密调节。1，2，3，4由骨分泌的成纤维细胞生长因子23使钠磷协同转运蛋白被肾和小肠细胞内化及抑制1，25-二羟维生素D合成。5 在1，25-二羟基维生素D作用下肾和小肠吸收钙及磷的效率增高(图1)。2，3，6 它也包括25-羟四- 24 -羟化酶的表达(CYP24)，且将1，25二羟基维生素D和25羟基维生素D异化成无生物活性，水溶性的维生素D3-23羧酸。2，3，4

It is one of the key pathogeneses of postmenapausal osteoporosis that estrogen deficiency leads to the decrease of OPG、TGFβ expression and the increasing expression of some bone-resorbing cytokines as OPGL、M-CSF and TRAIL, then stimulates osteoclast differentiation and activity, which potentiates bone resorption and bone loss:(2) ICI182780 shows partial transactivating function in osteoblasts, so it should belong to a kind of selective estrogen receptor modulators .

雌激素缺乏可能导致HOB中OPG、TGFβ的表达减少，而解除了对OPGL、M-CSF和TRAIL等刺激OC生成和活化的细胞因子的抑制作用，OC的数量和活性增加，导致骨吸收增强和骨量丢失，这是导致绝经后骨质疏松症的一个重要的发病机制；ICI182780在成骨细胞内表现出促转录活性，因此它并非纯ER拮抗剂，而应属于选择性雌激素受体调节剂(selective estrogen receptor modulator，SERM)。

Vascular endothelial growth factor is the most critical growth factor for angiogenesis, and matrix metalloproteinase-9 (MMP-9) is associated with extracellular matrix degrading and bone resorbing.

血管内皮生长因子(Vascular endothelial growth factor，VEGF)在血管的新生中起重要调节作用，基质金属蛋白酶-9(matrix metalloproteinase-9，MMP-9)可降解细胞外基质，引起骨吸收。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。