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To decrease maufacture costs and improve the ratio of efficiency and outlay.The not exensive emulsifier, hydrophobe and other adminicle were mixed with self-made polyesters, siloxane-polyester copolymers to obtain defoamers which be better than imported.And the factors in the process of compound were studied particularly and systemically.the prime project is as follows:the siloxane-polyester copolymer is synthesized with PPG2000,PEG400,1% hydrogen-containing Polyhydrosiloxanes, hexane diacid,which mol ratio of materials is 7:3:6:5.emulsifying agents are SP-60 and tw-60,the value of HLB is 8.5.its dosage is 5%.the concentration of control- bubble resin is 5%. the concentration of liquid hydrocarbon A is 20%.

为进一步降低消泡剂的生产成本,提高其使用时的效费比,采用价格低廉的乳化剂、疏水剂及其他助剂与所制聚醚酯、有机硅改性聚醚酯进行复配,制取了性能优于进口产品的优质消泡剂;并对复配工艺各要素进行了详细、系统的研究;最佳配方为:PPG2000、PEG400、含氢量1%的硅油,己二酸以物质的量之比为7:3:6:5制成的有机硅改性聚醚酯,乳化剂选择SP-60/TW-60组合、HLB值为8.5、用量5%,抑泡树脂用量5%,液态烃A用量20%,液态烃B用量10%,疏水剂用量15%~20%。

The course will start with an overview of the central and peripheral nervous systems, the development of their structure and major divisions. The major functional components of the CNS will then be reviewed individually. Topography, functional distribution of nerve cell bodies, ascending and descending tracts in the spinal cord. Brainstem organization and functional components, including cranial nerve nuclei, ascending / descending pathways, amine-containing cells, structure and information flow in the cerebellar and vestibular systems. Distribution of the cranial nerves, resolution of their skeletal and branchial arch components. Functional divisions of the Diencephalon and Telencephalon. The course will then continue with how these various CNS pieces and parts work together.

这门课将会从中枢和周边神经系统构造的发展和主要的分化点来概述,中枢神经系统的主要功能将会在复习中个别地说明:神经细胞体的断层以及功能性的分布、脊髓内上升和下降神经束的特征学和功能分布;脑干组织和功能要素,包括脑神经核、上升和下降神经束走向、含胺基酸脑激素细胞的分布、小脑和内耳前庭系统的构造和资讯传导流;颅神经的分布、骨弓和腮弓的演化;间脑和终脑的功能与分类;这门课将会探讨这些不同的中枢神经系统如何一起作用。

The influences of the type and dosage of the aldehyde, organic acids, as well as the water content in the reaction system on the racemization were examined in detail, and L-Glu was racemized quickly in the presence of 0.2 molar ratio of L-Glu to salicylaldehyde in acetic acid containing 20% water.

详细考察了醛的种类及用量、羧酸溶剂的种类、反应体系的含水量对消旋化的影响,结果表明L-谷氨酸在含20%水的乙酸溶剂中,以水杨醛作为催化剂(水杨醛与L-谷氨酸的物质的量比为0.2)的优化条件下可以快速地被消旋化。

Specifically, we will (1) perform electrophysiological study on the interaction of CTXs with cardiomyocytes stripped of specific GAGs,(2) study the binding of CTXs from spitting cobra venom with corneal tissue and examine the possible involvement of GAGs in the disruption of regular superstructure of collagen fibril and (3) examine the role of polyproline peptide sequence of P-type CTXs in the lytic action of CTXs. The results of this study will not only help delineate the mechanism of cobra CTXs, a long standing problem in the toxicity of cobra venom, but also suggest a new approach to develop CTXs into a potential drug for cancer.

本计划将进行:心脏细胞在去除醣胺基前后的电生理研究及比较了解心脏毒素与眼角膜的结合情形,并探讨醣胺基在维持眼角膜透明度所扮演的角色探讨P形心脏毒素中所含脯胺酸对细胞溶离能力的影响我们预期本研究将可对心脏毒素的作用机制有深入的了解,并寄望在未来能利用所了解的新作用机制,将心脏毒素发展成能控制癌症的新药方。

According to the result, we believed that the reason resulted in the low sensitivity was that the marker residue compound MQCA structure has changed after conjugated with protein and the antibody induced by the conjugation could not recognize the free MQCA in the ci-ELISA. Therefore we designed some hapten which could reserve the marker residue structural speciality mostly. After synthesis route selection and optimum, the hapten 7-Hydroxymethyl-3-methyl-quinoxaline-2-carboxylic acid was synthesized, used 4-methyl-2-nitroaniline as the start material via six steps, such as oxidation cyclization, bromize reaction, hydrolysis, Beirut reaction, reduction, hydrolysis. This work established basis for producing the high affinity antibody and developing the sensitive ELISA residue detection method.

本论文认为导致ELISA检测灵敏度较低的原因,是残留标示物和蛋白偶联后的特征结构发生改变,诱导产生的抗体不能够对游离MQCA很好的识别,因此,本论文设计了能够最大化保留MQCA结构特征的系列半抗原结构,并对其合成路线进行了筛选和优化,最终以对甲基邻硝基苯胺为起始原料,经氧化环化、溴代、水解、Beirut缩合、还原、水解六步反应制备含羟甲基结构的MQCA衍生物7-羟基甲基-3-甲基-喹噁啉-2-羧酸,为制备对游离残留标示物高亲和力的抗体,高灵敏度的ELISA残留检测方法的建立奠定基础。

Seven biogenic amines were extracted from a sample with 6% perchloric acid, then derivatized with benzoyl chloride. 0.02 mol/L borate buffer (pH 9.2) containing 0.06 mol/L sodium deoxycholate-methanol (95∶5, v/v)was used as a running buffer. The detection wavelength was set at 214 nm. The separation was achieved within 12 min. Good linearities were observed from the calibration plots in the concentration ranges.

样品经6%过氯酸萃取后,由苯甲酰氯衍生化,以含0.06 mol/L脱氧胆酸钠的0.02 mol/L硼酸(pH 9.2)-甲醇(体积比为95∶5)混合液为电泳介质,电泳电压25 kV,温度25 ℃,检测波长214 nm,在12 min内实现了7种生物胺的完全分离。7种生物胺的浓度与其峰面积在一定的范围呈良好的线性关系,检出限除组胺为15 μg/g外,其余均为5 μg/g。

Also with light tea alternate feed. 4, if necessary, go to the hospital drips, add water, electrolytes and glucose, to prevent dehydration and acidosis. 5, breast milk contains more lactose, most lactose enzyme decomposition of absorption and less by the Department at the end of fermentation to digest the lactose, producing gas, acid production, stimulate the intestinal tract, so that stool was diarrhea-like discharge. 6, breast and milk contain fat, part of being broken down into fatty acids and glycerol absorption, not alkaline digestion of fat in small granular form of calcium soap, so that stool can not appear in the first one to digest things.

还可与淡茶水交替喂。4、必要时去医院打点滴,补充水分,电解质和葡萄糖,以防脱水和酸中毒。5、母乳中含乳糖较多,大部分被乳糖分解酶分解吸收,少部末被消化的乳糖发酵、产气、产酸、刺激肠道,使大便呈腹泻状排出。6、母乳和牛乳均含有脂肪,一部分被分解为脂肪酸和甘油吸收,未被消化的脂肪碱性的钙形成小颗粒状的肥皂,使大便中出现消化不掉的一颗一颗的东西。

Cell lines were co-tranfected with bi-plasmids and cultured at 1% O〓 condition, luciferase assay demonstrated that all of the expression systems with different domains could be hypoxia-activated. GAL-CAD achieved more than 100-fold induction in A549 cell and more than 40-fold in HepG2; expression level of the system markedly increased after addition of glycin arm, almost 10-fold enhancement in HepG2 cell. Because basic expression also increased, the induction fold by hypoxia decreased.

双质粒共转染不同细胞株后,在1%O〓环境下培养24h,荧光素酶活性检测结果提示含不同结构域的表达系统均有受缺氧激活的能力,其中GAL-CAD在A549中获得100倍以上的诱导,在HepG2中获得40倍以上的诱导;加入甘氨酸臂后该表达系统的转录活性大为增强,在HepG2细胞中增强了10倍以上,但是由于基础表达也有所增加,受缺氧诱导的倍数下降。

The invention relates to a surface chemistry modified latex which can be obtained by carrying out radical polymerization in emulsion in the presence of at least one ethylenically unsaturated monomer or at least one polymer having ethylinically unsaturated residual bonds, at least one radical polymerization, at least one single, double or triple block polymer which is soluble or dispersible in water, comprising an active group at the end thereof, capable of forming a radical, and chosen from dithioesters, xanthates, thioether-thiones and dithiocarbamates.

本发明涉及具有改良表面化学性质的胶乳,它可以通过在以下物质的存在下进行自由基乳液聚合来获得:至少一种烯属不饱和单体或至少一种含残留烯属不饱和键的聚合物,至少一种自由基聚合引发剂,至少一种水溶性和/或水可分散的单嵌段、二嵌段或三嵌段聚合物,在其端部包括选自二硫酯,硫醚-硫酮,二硫代氨基甲酸酯和黄原酸酯中的能够形成自由基的活性基团。

When combined by heavy chromate-sodium hydrogen sulfite and by silane couplant, rapidly quenched NdFeB permanent magnetic particles, can form passive pycho-film (containing Cr〓O〓) and silane composite coating, which can improve greatly its oxidation resistance of NdFeB particles and increase the magnetic properties of bonded NdFeB Permanent Magnetic Composite .

采用重铬酸盐钝化-亚硫酸氢钠还原与硅烷偶联剂处理相结合来包覆处理快淬NdFeB永磁粉,能在快淬NdFeB表面形成致密的含Cr〓O〓钝化膜/硅烷复合涂层,它们显著地改善了快淬NdFeB的抗氧化性并提高了粘结NdFeB永磁复合材料的磁性能,并与其它的NdFeB包覆处理工艺所获得的涂层进行了比较。

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