吡啶基

In this paper,3-methoxy-5,6-diamino-2-nitropyridine was synthesized from 3,5-dichloropyridine by substitution,oxidation,nitration and ammoniation .

研究了以3-氯-5-甲氧基-2，6-二硝基吡啶为原料，通过甲氧化、硝化、氨化合成3-甲氧基-5，6-二氨基-2-硝基吡啶，该化合物的结构通过IR，1H NMR，MS和元素分析进行了表征，确认为目标化合物。

This invention is directed to the-tartaric acid salt of 2-amino-N-{1-(2,4-difluoro-benzyloxymethyl)-2-oxo-2-3-oxo-3a-pyridin-2-ylmethyl-2-(2,2,2-trifluoroethyl-2,3,3a, 4,6,7-hexahydro-pyrazolo(4,3-c) pyridin-5-yl-ethyl}-2-methyl-propionamide which is a growth hormone secretagogue and as such is useful for increasing the level of endogenous growth hormone.

本发明涉及2－氨基－N－{1－－(2，4－二氟－卞氧甲基)－2－氧代－2－3－氧代－3a－(R－吡啶－2－基甲基－2－(2，2，2－三氟－乙基)－2，3，3a，4，6，7－六氢化－吡唑子基(4，3－c)吡啶－5－基－乙基}－2－甲基－丙酰胺的－－酒石酸盐，它是一种生长激素促分泌素，并且可用于提高内源性生长激素水平。

Based on broad information collection, author compared and studied on the old synthesis process, and proposed the better process that started from benzyl chloride, then according to the sequence of " synthesis of benzylamine, synthesis of N-benzyl-N--acetamine, synthesis of 2-chloro-5-methylpridine ,2-chloro-5-trichloromethylpyridine,2-chloro-5-trifluropyridine " five steps to get the final product, CTFP.

本文在查阅大量文献资料和对2-氯-5-三氟甲基吡啶合成路线进行分析比较的基础上，提出了较佳合成路线，即以氯化苄为原料，合成的反应步骤为&苄胺&合成、&N-苄基-N--乙酰胺&合成、&2-氯-5-甲基吡啶&合成、&2-氯-5-三氯甲基吡啶&合成、&2-氯-5-三氟甲基吡啶&合成五步。

Seven 1-phenyl-(4-pyridinyl)acetylene derivatives were conveniently synthesized in this paper using corresponding styrylpyridines as starting materials by bromination, rearrangement and debromination.

本文采用简单易行的方法从苯乙烯基吡啶类衍生物通过溴化、重排和脱溴化反应合成了7种苯乙炔基吡啶类单体，研究了它们在1mol/L盐酸水溶液中的光环加成反应。

The key intermediate 3-methylaminopiperidine was synthesized from 3-methylaminopyridine by two methods,formylation and lithium aluminium hydride reduction or condensation with triethyl orthoformate and sodium borohydride reduction,and then hydr...

以3-氨基吡啶为原料，分别通过甲酰化反应、氢化铝锂还原和原甲酸三乙酯缩合、硼氢化钠还原两种方法得到3-甲胺基吡啶，最后经催化氢化得到中间体3-甲胺基哌啶。

Macrocycle with one pyridyl unit and one aryl oxdiazole unitCondensation of Ts-amino acids with 2,6-bishydroxymethyl pyridinegave di-esters in the presence of DCC and TsOH in pyridine. DMAP,another acylation catalyst was also discussed in our esterification.

二。含一个吡啶环和一个二苯基噁二唑单元：直接采用Ts保护的氨基酸与吡啶二醇在吡啶-TsOH反应体系中，在DCC作用下生成吡啶二醇二酯，讨论了酯化过程中不同酰基化试剂的应用。

Delayed Extraction Matrix Assisted Laser Desorption/Ionization Mass Spectrometrywas used to high resolution analysis of mix based DNA samples,using the binary matrices 3 HPA(3 Hydroxy 2 Picolinic Acid)/PAand substrate nitrocellose film.

本文使用延迟引出基体辅助激光解吸/电离质谱( DE- MALDI- MS)法，以3-羟吡啶甲酸和吡啶甲酸混合液为二元基体，硝化纤维膜为基底，对混合碱基组成的 DNA样品进行高分辨率测定，获得满意的结果：DNA2 0 - mer分子离子峰分辩率为 8769，DNA 36- mer为 1 650 ，DNA 54- mer为 843，前二者的组成分子离子峰各同位素峰清晰可辩。

Secondly,UV spectrophotometry was adopted to research the combination action on SM_2 and SIZ with MAA and 4-Vp.The combination action of functional monomer with template molecules were produced in the results. Then,the prediction imprinting principle of SM_2 and SIZ were given. The diagrams of infrared spectrum were analysed in MAA and 4-Vp and IMPs of SM_2. It was discoved that the absorbability peak of C=C function group in the IMPs were turn to be very low ,but the function group of carboxylic acid and pyridyl in the IMPs were no evidence change, and the condition was created in the molecular recognition of MIPs. Thermal Analysis was adopted to research IMPs ,in which ,a better thermal stability and its decompose temperature were showed in the results.

其次，本文利用紫外分光光度法研究磺胺二甲嘧啶和磺胺异噁唑与甲基丙烯酸或4-乙烯基吡啶的结合作用，结果表明，溶液中的功能单体与模板分子之间产生了结合作用，并预测磺胺二甲嘧啶和磺胺异噁唑印迹机理；分别分析了功能单体甲基丙烯酸、4-乙烯基吡啶、磺胺二甲嘧啶和磺胺异噁唑分子印迹聚合物的红外谱图，经过对比发现制得的印迹聚合物中C=C双键峰很小，并且功能键羧酸键和吡啶氮没有明显变化，这为聚合物特异识别特性创造了条件；利用综合热分析仪，对分子印迹聚合物进行综合热分析，结果表明分子印迹聚合物具有较好的热稳定性，分解温度也较高。

A one-step method for the synthesis of aromatic indolizine derivatives byintramolecular 1,5-dipolar cyclization reaction of 2-(2-arylethenyl)pyridinium N-ylidesin the presence of an oxidant has been studied for the first time. In the presence ofelectron-deficient olefins, however, 2-(2-phenylethenyl)pyridinium N-ylides underwent1,3-dipolar cycloadditions and then aromatized in situ by TPCD to produce indolizinederivatives, indicating 1,3-dipolar cycloaddition proceed more readily than 1 ,5-dipolarcyclization in these conditions. Pyridinium disubstituted N-ylides, readily obtainedfrom corresponding pridinium and β-chlorovinyl ketone, underwent thermalintramolecular 1,5-dipolar cyclization to give indolizine derivatives easily.Indolizinecarbaldehyde derivatives were synthesized starting from 2-pyridinecarbaldehyde in four-steps involving 1,3-dipolar cycloaddition reaction.

本文首次研究了2-(2-芳基乙烯基)吡啶N-叶立德在氧化剂存在下的分子内1，5-偶极环化反应，采用一锅法合成了中氮茚衍生物；研究了这些N-叶立德的1，5-偶极环化和1，3-偶极环加成反应的选择性，发现当有缺电子烯烃存在时，优先进行1，3-偶极环加成反应，而不再发生分子内1，5-偶极环化反应；由β-氯乙烯酮方便地得到了烯丙基N-叶立德，他们在加热时进行分子内1，5-偶极环化反应而得到中氮茚衍生物；由2-吡啶甲醛为起始原料，通过1，3-偶极环加成反应等四步反应，得到了重要的中氮茚甲醛衍生物，这些反应都具有条件温和和操作简便的特点，是合成中氮茚衍生物的新方法。

A process for synthesis of-2-{[4-(3-methoxypropoxy)-3-methyl-pyridin-2-yl]methyl- sulfinyl}-1H-benzimidazole from 2,3-lutidine was studied.

以2，3-二甲基吡啶为起始原料，经过11步反应，不对称合成了质子泵抑制剂的关键中间体：-2-{[4-(3-甲氧基丙氧基)-3-甲基吡啶-2-基]甲基亚硫酰基}-1H-苯并咪唑。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。