吡啶基

Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.

以2-氯－4-硝基苯酚和2-氯甲基吡啶为起始原料，经醚化、硝基还原得到3-氯－4-（吡啶－2-甲氧基）苯胺，3-氯－4-（吡啶－2-甲氧基）苯胺与3-氰基－6-乙酰氨基－7-乙氧基－4-氯喹啉反应得到3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉，3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉去乙酰保护基后，与-4-二甲氨基－2-丁烯酰氯经酰化反应得到ner-atinib。

Salt 8 exhibits an ICT absorption band at lmax572 nm in ethanol, which does not correspond to any of the TTF or pyridinium moieties, and obeys the Beer–Lambert law.

盐 8展品的信息和通信技术的吸收带在572 nm的lmax 乙醇，这不符合任何信托基金或吡啶基，并服从啤酒兰伯特法。

It was reported that benzylidenemalononitrile did not react with 1-benzyl-1,4-dihydronicotinamide. However, similar reaction easily takes place under the same condition when the phenyl group is replaced by the pyridyl group.

本课题组之前报道了苯亚甲基丙二腈在室温下不能被BNAH所还原，本论文将反应底物中的苯基换成吡啶基之后，在同样的实验条件下，反应可以比较顺利的进行。

Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring, to which is attached a 5-membered heterocyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

本发明涉及含有连接在5元杂环上的稠合至环烷基或者杂环的苯基或者吡啶基环的二环化合物，包括其药学上可接受的盐和前药，它们是G蛋白偶联受体40(GPR40)激动剂并且可以用作治疗性化合物，特别是在2型糖尿病和与这些疾病相关的症状中用作治疗性化合物，这些症状包括肥胖病和脂质疾病，比如混合或者糖尿病型血脂异常症、血脂质过多、高胆甾醇血和高甘油三酯血症。

Divinylpyridine-9,9′-diethylfluorene nanoparticles were prepared by reprecipitation method.

利用二次沉淀法制备出不同粒径(101.6~516.9nm)的2，7-二乙烯吡啶基-9，9′-二乙基芴有机纳米微粒。

Chlorpyrifos mehtyl with different dosages of 3,5,10 mg/kg compared with malathion 15 mg/kg in grain silo,each contented 40 thousand kilograms of rice was studied.To be sprayed by machine when loading to silo and to be observed two years through all experiment,the effective control to sitophilus zeamais of chlorpyrifos mehtyl 5 mg/kg can be protected more than six months,and 10 mg/kg over one year.

报道了甲基毒死碑(化学名称为二甲基O-3，5，6-三氯-2-吡啶基硫逐磷酸酯)3、5、10 mg/kg不同剂量，以防虫磷15 mg/kg作比较，在立筒库星仓内，每筒40000 kg稻谷，机械喷雾法处理，储藏二年，经生物测定对玉米象药效，甲基毒死蜱5 mg/kg可达半年以上，10 mg/kg可达一年以上防护期。

Structural analysis reveals that the assemblies of these complexes are mainly directed by counter anions, followed with the change of anions from simple inorganic species (SCN~-/dca/Cl~-) to organic ones (ip/nip/tp/chdc), diversiform structures are formed varying from mononuclear, tetranuclear molecules to infinite 1-D and 2-D frameworks.

第三章利用4-bpt的同分异构体4-氨基-3，5-双(2-吡啶基)-1，2，4-三唑(2-bpt)作为螯合试剂，与多种无机/有机阴离子以及金属Cd~盐反应，得到了一系列Cd~配位化合物(7-15)。

With good stability and high reactivity, pyridine-based tridentate N-ligands have been widely used in the fields of coordination chemistry, organic synthesis and homogeneous catalysis.

吡啶基含氮三齿配体具有良好的稳定性和反应活性，在配位化学，有机合成和均相催化中均得到了广泛的应用。

Meanwhile,the behavior of the complexation between the sulfonated SEBS ionomers and pyriding-containing random coploymers both in dilute solution and in bulk was evidenced by an abnormal increase of the viscosity and Tg .

SEBS磺酸盐离聚物与含吡啶基的无规共聚物在稀溶液和本体中能形成分子间的络合物，这从共混物溶液粘度的反常增大和本体Tg的显著增加得到了证明。

Nucleic acids were determined at nanogram levels based on their enhancement effects on the fluorescence reaction system between H 2O 2 and p hydroxyphenylacetic acid catalyzed by Mn [tetrakis(3 N methylpyridiniumy)porphyrin],a mimetic peroxidase.

痕量核酸对meso 四(3 N 甲基吡啶基)卟啉合锰催化H2 O2 氧化对羟基苯乙酸的荧光反应产生增强作用，且增强程度与核酸浓度之间有良好的线性关系，据此建立了测定核酸的高灵敏的荧光分析方法。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。