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The details of this route as follows:With the piperidine as catalyst, p-hydroxylbenzaldehyde condensed with thiazolidine-...

同时,本文还对反应过程中产生的5-乙基-2-乙烯基毗啶、5-乙基-2-羟乙基吡啶、5-[(4-羟基苯基)甲基]-2,4-噻唑烷二酮、5-4-

It has been demonstrated that the methods are successfully used for QSRR studies of quinazoline derivatives, alkypyridine, haloid alkane, ketone, alcohol, sulfur alcohol compounds.

本文成功地用该方法对喹唑啉类、烷基吡啶化合物、卤代烃、醇、羰基化合物和硫醇化合物的结构保留关系进行了探讨。

Quinoline co-substrate biodegradation with other compounds such as glucose, phenol and pyridine were analyzed.

研究了喹啉与葡萄糖、吡啶、苯酚等物质共基质时的生物降解情况。

Molecularly imprinted polymers of sulfamethazine(SM 2 ) were prepared with silica gel as a sacrificial material, methacrylic acid and 4 vinylpyridine(4 Vp) as functional monomers, glycol dimethacrylate as crosslinker. The polymer properties were investigated by static adsorption experiments. Scatchard analysis shows that the adsorption ability of MAA MIP is superior to that of 4 Vp MIP. The dissociation constant of MAA MIP is 9 59×10 -4 mol/L. The value of apparent binding a...

以磺胺二甲嘧啶为模板分子,分别用甲基丙烯酸和4乙烯基吡啶为功能单体,二甲基丙烯酸乙二醇酯为交联剂,采用牺牲硅胶法合成了磺胺分子印迹聚合物,通过静态吸附实验,系统研究了不同单体对聚合物识别性能的影响;Scatchard分析表明,以甲基丙烯酸为单体的聚合物具有较高的吸附能力,其离解常数Kd为959×10-4mol/L,最大表观结合位点数Qmax为3070μmol/g。

Three methods are used to prepare molecular imprinted polymers,which include conventional bulk technique or polymerization with ultraviolet initiated in low temperature and polymerization with silica-gel as sacrificial materials. In the polymerization procedure , Sulfamethazine(SM2)and Sulfisoxazole were used as target template molecules, methacrylic acid and 4-vinylpyridine(4-VP) and acrylamide were selected as functional monomers, ethylene glycol dimethacrylate as crosslinker, azobisisobutyronitrile was used as initator.

主要工作如下:首先,以磺胺异噁唑和磺胺二甲嘧啶为模板,分别以4-乙烯基吡啶,甲基丙烯酸,丙烯酰胺为功能单体,以二甲基丙烯酸乙二醇酯为交联剂,偶氮二异丁腈为引发剂,采用了传统方法(60℃恒温水浴)、牺牲硅胶法及低温紫外光聚合法等三种方法合成了一系列的磺胺类药物印迹聚合物。

Ag-Au alloy nanoparticles; Surface Enhancement Raman Scattering; thiophenol; p-Aminothiophenol; 2; 2'-bipyridine 2; 2'-bpy

Ag-Au合金纳米粒子;表面增强拉曼散射;苯硫酚;对巯基苯胺; 2; 2'-联吡啶2; 2'-bpy

Via comprehensive computations, the possibilities of vinylidene and allene intermediates were excluded, and the reaction mechanism was found to contain the following three steps:(1) gold-catalyzed cyclization to give the cyclic intermediate,(2) the cyclic intermediate undergoing a 1,3-H migration to give a more stable intermediate, with the assistance of water-cluster,(3) finially, the 1,2-H or 1,2-silyl migration occuring for generation of the observed product.

通过对各种可能的反应路径的进行计算和比较,排除了亚甲基卡宾和连二烯中间体的可能性,并确定该异构化反应机理包含以下三个步骤:(1)炔丙基吡啶反应在金催化条件下发生分子内的成环得到环状中间体;(2)环状中间体在水分子簇的协助下优先发生1,3-氢迁移反应,异构化得到更为稳定的中间体;(3)最后再进行1,2-氢迁移或是1,2-硅烷基团迁移即得到实验中所观察到的环异构化产物。

Rizaben was synthesized directly from anthranilic acid ,3,4- dimethoxy cinnamic acid, and benzene sulfochloride using 3EA/pyridine as compounded solvent.

采用3EA/吡啶复合溶剂,以邻氨基苯甲酸、3,4-二甲氧基肉桂酸和苯磺酰氯为原料直接合成曲尼司特。

The PVp-4 show a two-peak phenomena in melting process indicating every polymer consists of two components with different thermal property.〓CNMR spectrums embody a atactic chain structure.

在对催化4-乙烯基吡啶和丙烯腈的均聚合研究中,考察了新型催化剂中Ti/Co配比、β-二酮种类以及助催化剂、溶剂种类、载体化方法等因素在不同反应条件下对聚合的影响。

Based on the synthesis method and the function of decreasing blood glucose levels of rosiglitazone, and the report on benzoquinones which resulted in a significant decrease in blood glucose levels, a novel non-thiazolidinedione class of PPARy agonist 2, 5-Dihydroxy-3-{4-[2-(methyl- pyridin-2- yl-amino)- ethoxy] -phenyl}-6-phenyl-[l, 4] benzoquinone (4) was designed and synthesized.

在合成罗格列酮的基础上,根据某些醌类结构化合物的类似胰岛素作用,设计并合成了一种非噻唑烷二酮类PPARγ激动剂2,5-二羟基3-{4-[2-(甲基-2-吡啶氨基)-乙氧基]-苯基}-6-苯基-1,4苯醌(4)。

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