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Objective To investigate the degeneration of dopaminergic neurons induced by MPP+ in mouse mesencephalic dissociated culture.

目的:探讨1-甲基-4-苯基-四氢吡啶离子(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,MPP+)诱导小鼠胚胎中脑原代培养多巴胺能神经元损伤。

Objective To investigate the degeneration of dopaminergic neurons induced by MPP+ in mouse mesencephalic dissociated culture and establish the cell model for parkinson'[KG-*3]s disease research in vitro.

目的: 探讨1-甲基-4-苯基-四氢吡啶离子对小鼠胚胎中脑原代培养多巴胺能神经元的毒性作用及其机制。

ATRP initiation systems consist of organic chloride initiators (RCl, RBr or aryl sulfonyl chloride, etc.), transition-metal catalysts in lower oxidation state Cu(I, Fe, Ru, Ni, etc. and organic electronic-donating ligands (2,2'-bipyridine―bipy or bpy, PPh3, multidentate ligand compound 1,1,4,7,7-pentamethyldiethylenetriamine, etc.).

普通ATRP引发体系包括引发剂主要为氯或溴化物,芳基磺酰氯;低价过渡金属卤化物如Cu, Fe,Ru,Ni等;有机配体如2,2'-联吡啶,PPh3,脂肪族多元胺等。

BioMarin Pharmaceutical Inc.(NASDAQ: BMRN) has acquired Huxley Pharmaceuticals, Inc. Huxley Pharmaceuticals, Inc. has rights to a proprietary for of 3,4-diaminopyridine, amifampridine phosphate, for the autoimmune disease Lambert Eaton Myasthenic Syndrome.

拜玛林制药公司(NASDAQ:BMRN)已经收购了赫胥黎制药公司赫胥黎制药公司已3,4 -氨基吡啶的专有权利,amifampridine磷酸盐为自体免疫性疾病朗伯Eaton肌无力综合征。

Linear dimerization of isoprene to form myrcene ;2. Synthesis of Unsaturated Cyclothioethers byCycloaddition Reactions of Myrcene;3. The traditional synthesis is by the way of Diels-Alder reaction of myrcene with acrolein over Lewis acid catalysts in organic solvent.

二烷基咪唑或烷基吡啶卤化物与ZnCl2 构成一类新型的具有Lewis酸性的离子液体,以其为催化剂和反应介质,通过月桂烯与丙烯醛的Diels Alder反应高区域选择性地合成了对位柑菁醛。

The intercalation reaction of nonaromatic heterocyclic compound hexahydropyridine into α-ZrP was reported for the first time.

磷酸氢锆α-Zr(HPO4)2.H2O是一类典型的层状结构的多功能材料,本文首次报道了非芳香杂环化合物六氢吡啶对α-ZrP的插层反应。

In pH=2.0 sulfuric acid solution, 2,2′bipyridine, an almost nonluminescent compound was transformed into a highly fluorescent compound (λex=340 nm,λem=430 nm) when attacked by ·OH generated by Fenton reaction.

在酸性介质中,Fenton反应产生的羟基自由基能将几乎无荧光的2,2′-联吡啶氧化成强荧光物质,羟基化产物的最大激发和发射波长分别是340 nm和430 nm。

1M of iodide was optimized parameter of electrolyte in this research. Furthermore, the TiO2 film gave a higher conversion efficiency than the TiO2 film nontreated by 4-tertbutylpyridine, which increased 13% by surface treatment with 4-tertbutylpyridine.

在碘浓度为0.1M时为此实验电解液之最佳参数,另外TiO2薄膜电极通过4-叔丁基吡啶的处理,染料敏化太阳能电池之转换效率较未处理电极高出了13%。

In the thesis, a series of novel single and multi-armed oxadiazole bridging ligands and pyridyl-4, 5-imidazole dicarboxylic acid ligands have been synthesized. The coordination chemistry of these novel ligands with transition metal ions was investigated. In addition, two 1, 3, 4-oxadiazole bridging ligands end-capped by chelating Schiff-base coordination sites have been designed and synthesized. The coordination chemistry based on one of the two ligands with metal ions was primarily investigated.

本文报道了一系列新颖的含1, 3, 4-Oxadiazole杂环的单臂及多臂有机配体,研究了它们与过渡金属离子的配位反应化学;合成了吡啶基-4,5-咪唑二羧酸有机配体,研究了它们在水热条件下与过渡金属离子的配位反应化学;另外,还合成了1, 3, 4-Oxadiazloe杂环桥联的双Schiff-base有机配体,初步探讨了其与过渡金属离子的配位反应化学。

Polyacence, polypyridinopyridine and paracyanogen molecules have been studied by using quantum chemistry MNDO, 1D tight-binding CNDO/2-CO methods.

采用MNDO、一维紧束缚CNDO/2 CO方法研究聚并苯、聚并吡啶及多聚氰的分子结构,揭示结构稳定性和电荷分布的变化规律。

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