吖啶基

The benzylpiperidine derivatives show high activity of inhbiting against AChE in vitro, some of them are even more potent than -Hup A and Tacrine.

苄基哌啶类衍生物的胆碱酯酶活性发现，其与四氢吖啶的衍生物对AChE的抑制活性超过石杉碱甲和Tacrine。

These chemical shifts in the aromatic region of the resulting nucleophilic adduct 2-F were consistent with the counterparts of 9,10-dihydro-9-methoxy-9-(4-methoxyphenyl)-10-methylacridine, 17b which was proven to be the adduct of the 9-phenyl acridinium salt formed with an excess of MeOH (Figure S7 in Supporting Information).

在最终的亲核加成化合物2-F的芳香族区中的这些化学位移与9，10二氢-9-甲氧基-9-(4甲氧基苯基)-10-甲基吖啶的对应物是一致的，17b 这被证明是与过量的MeOH形成的9-苯基吖啶盐的加成化合物（支持信息中的图S7）。

N butyl 2 ethoxy thioacridone ; acridone ; electron transfer ; fluorescence

N-丁基-2-乙氧基硫代吖啶酮；吖啶酮；电子转移；荧光

The results showed that upon Xe lamp irradiation,N butyl 2 ethoxy thioacridone was transformed into corresponding acridone and the presence of the lattter was confirmed by UV visible absorbtion spectrum and mass spectrum.

结果表明：在Xe灯光照下，N 丁基 2 乙氧基硫代吖啶酮转变成了相应的吖啶酮，用紫外可见光谱和质谱证实了吖啶酮的存在；生成的吖啶酮可被二苯基碘盐猝灭，它们之间的荧光猝灭遵循电子转移的反应机理。

Acridone 1 reacted with benzyl chlorides 2 in NaH/DMF/KI to give 10-benzyl-9-acridones 3 in high yields. Subsequent reduction of 3 with NaBH4 gave 10-benzy1-9,10-dihydroacridine derivatives 4 with yields of 88%～96%.

吖啶酮1与氯化苄及其衍生物2在氢化钠/N，N-二甲基甲酰胺/碘化钾中反应高产率生成10-苄基吖啶酮类化合物3； 3经硼氢化钠氢化还原生成10-苄基-9，10-二氢吖啶类化合物4，产率88%～96%。

Aniline compounds are used as raw material and reacted with anthranilic acid and then phenyl iodide as alkylating agents to give alkylating products followed by cyclizing with concentrated sulphuric acid to give a N-phenyl-acridone(or 3-ethoxyl-N-phenylacridone).The structure of intermediate and target compound are determined by IR and MS.

以苯胺类化合物为原料，先后以邻氯苯甲酸和碘苯为烷基化试剂进行了N 烷基化反应，再用浓硫酸使其环化制得N-苯基吖啶酮和3-乙氧基-N-苯基吖啶酮，并用红外光谱及质谱仪检测了各中间体及目标产物的结构。

In this thesis, investigations focused on heteropoly acids-catalyzed C-C and C-N bond formation reactions and the synthesis of xanthenediones and acridinediones under thermal conditions are described.1.12-Phosphotungstic acid has been used as an efficient,eco-friendly,and air- and moisture-stable catalyst to promote the direct dehydrative substitution of the hydroxy group of benzylic and allylic alcohols with variousβ-dicarbonyl compounds.

本篇论文主要描述了杂多酸催化下的C-C和C-N键的生成，以及无溶剂直接加热下合成十氢氧杂蒽二酮和9-芳基十氢吖啶二酮。主要内容如下：1。在磷钨酸催化下，1，3-二羰基化合物与醇能够顺利偶合，脱除一分子的水，生成烷基化的1，3-二羰基化合物。反应在甲苯中进行时，二芳基甲醇能与各类1，3-二羰基化合物反应，成率很高；但对于1-苯乙醇，只能得到很低的产率。

Mol/L. 3 A study on the ECL of acridinum esters including 10--acridinium-9-carboxyl-phenyl-ester iodinate and 10-methyl-9-(p-formylphenyl)-acrdiniumfluorosulphonate in neutral solution was carried out. It was found both CACPEI and MFPA give strong ECL in KNO〓 solution when an appropriate voltage was applied on Pt electrode.

本文研究了碘化10-乙羧基吖啶-9-羧酸苯酯和对甲酰基苯基-10-甲基吖啶-9-羧酸酯氟磺酸盐的ECL行为，发现在中性KNO〓介质中，这两种吖啶酯都能在一定的电位下产生很强的ECL信号，考察了各种影响因素，确定了发光的最佳条件，探讨了可能的发光机理。

The largest chemical shifts were observed for the proton 1.48 ppm adjacent to the central pyridinium ring and para-protons 1.47 ppm with respect to the nitrogen of pyridinium.

在最终的亲核加成化合物2-F的芳香族区中的这些化学位移与9，10二氢-9-甲氧基-9-(4甲氧基苯基)-10-甲基吖啶的对应物是一致的，17b 这被证明是与过量的MeOH形成的9-苯基吖啶盐的加成化合物（支持信息中的图S7）。

Three kinds of fluorescence polymer with the structure of acridine yellow were synthesized and the sensor for measuring nucleic acid was also fabricated.

论文第三部分开展了以荧光高分子为敏感试剂的新型光化学传感器载体研究，合成了N，N-二甲氨基对苯甲醛缩醛类聚合物，考察了苯环上不同取代基对荧光性能的影响，研究了该类敏感膜对乳酸、尿嘧啶、胸腺嘧啶和腺嘌呤的响应性能；合成了三种具有吖啶黄结构的荧光高分子，制成了测定核酸的传感器。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。