向细胞的

Objective: To investigate the differentiation of cultured adipose derived stem cells to myocardial cells in vitro.

目的：研究诱导体外培养脂肪干细胞向心肌细胞分化的方法。

The effect of rhBMP-2 on differentiation and proliferation of the stem cells was studied by determination of ALP and MTT activity.

探讨体外条件下rhBMP-2诱导脂肪来源干细胞向成骨细胞分化和增殖的情况，并观察其量效关系。

Objective To investigate the effects of aluminum on differentiation of rat neural stem cells in vitro.

目的 探讨铝对大鼠神经干细胞向神经元样细胞分化的影响。

The patterns of amyloplast proliferation behaved "amyloplast envelop dilating, evaginating, and budding to form new amyloplast","amyloplast envelop constricting to form new amyloplast","form new amyloplast as the middle clapboard" and "amyloplast envelope dilating and invaginating to form new amyloplast".

玉米胚乳细胞淀粉质体增殖有"被膜出泡、外凸，以出芽方式形成淀粉质体"、"淀粉质体被膜缢缩形成淀粉质体"、"以中间隔板形式形成淀粉质体"及"淀粉质体被膜向内出泡，在淀粉质体内形成新的淀粉质体"等几种方式。

Nerve repair at the level of spinal cord appeared as a new but challenging technique. The better understanding of regeneration from neurons and further refinement of instruments may push the brachial plexus surgery to a new level. Sensory and motor differentiated nerve coaptation plays an important role in the free neurovascular muscle transplantation due to the significance of motor axons for the flap reinnervation.

脊髓水平的神经修复是一个新而具有挑战性的技术，对神经元再生的深入理解（包括神经元误向生长与存活问题）与实验手段的完善（包括基因调控的成纤维细胞和雪旺细胞种植等），将使臂丛外科进入一个新的水平。

Epidermal cells near the wound dedifferentiate and proliferate forming blastema and/or migrate to the wound plane forming a pre-epidermis consisting of several layers of stem cells covering the wound plane, which then re-differentiates further forming fully developed epidermis. Cells in the parietal peritoneum are also induced by injury to dedifferentiate into stem cells which then proliferate and migrate along the parietal peritoneum to the wound place forming a pre-peritoneum which re-differentiates into fully developed parietal peritoneum.

伤口愈合包括伤口闭合、顶端表皮层及体腔上皮的新生：创伤后的前4 d，残腕顶端的肌肉组织向伤口处迁移并重排使伤口闭合；创伤附近的表皮层细胞发生脱分化并增殖后迁移到创伤面形成由数层干细胞组成的前表皮层，之后进一步分化形成表皮层；而体腔上皮细胞在创伤诱导下也脱分化并增殖，然后沿体腔上皮迁移到创伤处形成&前体腔上皮&，经再分化形成新的体腔上皮。

The transforming growth factor-β superfamily, a large group of highly conserved growth factors including TGF-βs, activins and BMPs, regulate a wide variety of cellular functions such as proliferation, differentiation, apoptosis and migration. Signals from these growth factors are transduced by a group of Smad proteins. To date, there are nine vertebrate Smads, including the receptor-activated Smads , Smadsl-3, 5 and 8, the common mediator Smad4 and Smad4β, and the inhibitory Smads, Smad6 and 7. Signaling is initiated when the ligand induces assembly of a heteromeric complex of type Ⅱ and type Ⅰ TGFβ receptors. Then R-Smads are directly phosphorylated by activated type I TGF-β receptors.

在多种SMADS中，SMAD5令我们产生兴趣，基于三个原因：1、Smad5基因敲除胚胎中发现卵黄囊的异位造血以及CFU-GM祖细胞数目增加，表明SMAD5可能是早期造血发育的负向调控基因。；2、应用反义核酸封闭Smad5可以逆转TGF-β对祖细胞增殖的抑制效应，表明它可能介导TGF-β信号转导，后者的异常，包括某些SMADS的功能异常，和白血病紧密相关；3、Smad5基因定位在人染色体5q21，此区域的缺失和急性髓系白血病和骨髓增生异常综合症相关，因此，Smad5被怀疑为白血病抑制基因。

The expression of AT2R gene can be regulated efficiently in vivo by local delivery of MSC with dual-stable expression of AT2R gene, thus reduces the formation of intimal hyperplasia.④AT2R gene can influence the expression of ECM and significantly promote the cellular apoptosis in the injury rat carotid artery.⑤These data demonstrate the clinical potential of AT2R regulatable expression to prevent restenosis after PCI.

研究结论：(1)与VSMC直接接触可以诱导MSC向血管成分细胞分化；(2)构建的Dox-on可调控的MSC细胞株诱导活性可靠，使外源AT2R基因的表达处于有效的主动控制下；(3)局部导入MSC不影响球囊损伤后大鼠颈动脉新生内膜增生；(4)由MSC介导的AT2R可调控表达受到Dox的良好调控，可有效抑制球囊损伤后大鼠颈动脉新生内膜增生；(5)AT2R影响血管损伤后修复时ECM成分的表达，并促进细胞凋亡的发生，可能是AT2R介导抑制新生内膜形成的机制。

The sac structure projected through the pollen aperture possesses the typical nature of transfer cell, i. e complex lybrinthian wall ingrowth and abundant mitochondria, RER, dicotysomes and ribosomes under the wall. Its outer surface is closely related to the tapetal protoplast. The accumulation of storaged material in pollen start at the area near the apertures. Above restults indicate the pollen apertures may be the"door"from where nutrition flows into pollen in P. hortorum.

绒毡层物质向花粉粒的短途运输明显的表现在花粉的萌发孔区，一方面形成向外突起的囊腔，另一方面在这里具有发达的壁迷宫，而且迷宫下具丰富的线粒体，RER和高尔基体等细胞器，此外花粉内贮藏物的大量积累首先从萌发孔附近开始以及萌发孔处与绒毡层有紧密接触都说明天竺葵花粉萌发孔可能是物质进入花粉的&门户&。

"If you drink too much water it lowers the concentration of salt in your blood so that it is lower than the concentration of salt in cells," says Professor Robert Forrest, aconsultant in clinical chemistry and forensic toxicology atthe Royal Hallamshire Hospital in Sheffield.

正如上一节所说，如果喝太多的水，人体血液中的盐浓度比细胞中的浓度还低，水就会从稀释的血液中移向水较少的细胞和器官，而这将引起相应的器官的膨胀，引发身体失调的严重后果。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。