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Results The main CTimages of adrenal neuroblastoma in children were bigger extrarenal tumor ,included :huge and irregular mass(6 cases ),regular mass (2 cases),calcification (87cases),cystic degeneration or necrosis (1cases),bleeding(2cases),crossing of the midline (5cases),wrapping retroperitoneal major vessels (4cases),retroperitoneal enlargement of lymphnode (7 cases),The masses were heterogeneous enhancement.

分析2004年10月~2008年10月经手术病理证实的8例儿童肾上腺神经母细胞瘤的CT表现,如形态,密度及周围结构变化情况,结合临床资料,进行综合评价。结果儿童肾上腺神经母细胞瘤为肾外体积较大肿块,其中不规则肿块6例,规则2例,钙化7例,囊变坏死1例,出血2例,越过中线5例,包绕腹膜后大血管4例,腹膜后淋巴结肿大7例,肾脏向后外侧移位6例。

Focal cerebral ischemia activates intrinsic neural stem cells, which proliferate and differentiate, and migrate toward ischemic striatum and frontoparietal cortex. This may help clarify the mechanism of functional recovery after ischemia.

脑缺血时诱导内源性神经干细胞增殖、分化,并向缺血纹状体和皮质迁移,此现象有助于阐明神经功能康复的机制。

Operative design: After gastric anterior wall was exposed, any Crow's nerve was identified from antral surface nearby gastric angle. Along the Crow's nerve, Latarjet nerve was found, gastric branches of Latarjet were gradually severed, the dissection proceeds to up towards the diaphrageal fissula, and then, the right gastroepiploic neurovascular bundle was cut, the distal two-thirds of the greater curvature was mobilized by dividing the greater omentum, the posterior nerve of Latarjet may be seen and isolated in the same way.

手术设计:暴露胃前壁,自胃角附近的胃窦壁表面任意找到一支&鸦爪&支迷走神经,随以此支为标志向上找到分出该鸦爪的Latarjet氏神经干,顺该神经向上游离,分离中避开向右走行的肝支及胃小弯的主要血管,逐一切断走向胃壁的迷走神经分支,直游离到膈肌食管裂孔平面。

Retinal ganglion cells carry signals out of the eye to the lateral geniculate nuclei.

视网膜神经节细胞运载信号在眼睛外面对侧向膝状的神经核。

The result showed that, the body wall most outer layer cuticle assumesthe translucent porodine, the surrounding entire body wall; Close isconnected with the cuticle 表皮层 for 合胞体 the structure, inthe back, the abdomen and its two sides separately adds thick to inprominent Cheng Jizhuang, separately contains the back side,腹侧the nerve and compares to the developed back, the abdomen nerve; Themyo- position to the body wall most inner layer, has the muscle cellto arrange becomes; Between the body wall and the digestive tractcavity is a body cavity; Digestive tract for 肌质 structure, afterinference for roundworm's esophagus.

结果显示,体壁最外层的角质层呈半透明的胶状,包围整个体壁;与角质层紧密相连的表皮层为为合胞体构造,在背、腹及其两个侧面分别加厚向内突出成脊状,分别包含背侧、腹侧神经和相比对发达的背、腹神经;肌层位于体壁最内层,有肌细胞排列而成;体壁与消化道之间的空腔为体腔;消化道为肌质结构,经推断为蛔虫的食道。

At this level, the upward projecting signals to higher-located centres and signals that eliciting spinal reflexes are subjected to complex modulatory effects coming from the descending fibers from supraspinal structures and propriospinal neurons through releasing some neuroactive substances, including neurotransmitters and neuromodulalors.

在这里,来自脊髓上结构的下行纤维和脊髓本身的局部神经元通过释放各种神经活性物质,包括神经递质和调质,对痛信号向高位中枢的上行传递和引起脊髓局部反射的过程,起着复杂的调制作用。

In fact, cells with NSCs-like properties are likely to occur throughout the adult CNS, but they are able to give rise to neurons in only a few restricted areas in vivo, i.e., the subventricular zone in the wall of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus. Very poor regenerative capability of the adult mammalian CNS could be explained as follows: first, theneuronal differentiation of endogenous NSCs may be inhibited by microenvironmental factors present in most areas of the adult CNS.

成年哺乳动物中枢神经系统可怜的再生能力可能主要归结于两方面的原因:第一,成年动物中枢神经系统内的大多数区域存在一些特殊的微环境因素,它们抑制了内源性神经干细胞向神经元方向的分化;第二,内源性神经干细胞的数量太少,不足以形成有效的自我修复。

Objective To study the pathogenesis and clinical symptoms of patient with central type of interˉvertebral disc protrusion manifested intermittent claudication as the mainly clinical presentation,so as to reach the early diagnosis and treamtmet in time.Methods In58cases,X-ray film,lumbar discography,CT examinations were done to confirm the diagnosis,then total laminectomig was performed to reveal the vertebal body without involving small arˉticular process.Intervertebral tissue was excised via duralotomy approach in2cases in remaining56cases,through right and left longitudinal syndesmotomy to resect the nucleus pulposus of lumber intervertebral disc.Results In58cases treated by operation,the operative findings were in according with the X-ray and CT examinations ofpre-opˉeration.

目的 对呈间歇性跛行主要临床表现的中央型椎间盘突出症患者的发病机制和临床表现进行研究,达到早诊断、早治疗方法对58例患者进行X线拍片,腰椎碘造影,CT扫描检查,根据检查结果确诊后,采用全椎板切除显露椎体,未累及小关节突,2例经硬膜切开入路切除间盘组织,余56例经从双侧用神经剥离子带棉片将硬脊膜带神经根向中线剥拉至显露圆形突出物止,分别从左右纵韧带摘除髓核。

Methods In58cases,X-ray film,lumbar discography,CT examinations were done to confirm the diagnosis,then total laminectomig was performed to reveal the vertebal body without involving small arˉticular process.Intervertebral tissue was excised via duralotomy approach in2cases in remaining56cases,through right and left longitudinal syndesmotomy to resect the nucleus pulposus of lumber intervertebral disc.Results In58cases treated by operation,the operative findings were in according with the X-ray and CT examinations ofpre-opˉeration.

对58例患者进行X线拍片,腰椎碘造影,CT扫描检查,根据检查结果确诊后,采用全椎板切除显露椎体,未累及小关节突,2例经硬膜切开入路切除间盘组织,余56例经从双侧用神经剥离子带棉片将硬脊膜带神经根向中线剥拉至显露圆形突出物止,分别从左右纵韧带摘除髓核。

In order to further investigate the relationship of SP and ESCs, we design two level experiments —in vitro and in vivo. In vivo, firstly, We establish the nomal rat full-thickness wounds model, and employ integrin β1 keratin 19(K19)、 keratin 15(K15)、 Brdu as ESCs markers to conform the existence of ESCs in the granulation tissue of Group Capsaicin (rats were subcutaneously injected capsaicin pre-injury to damage sensory neuron and block the secretion of neuropeptides), Group Control, and Group SP (rats were injected SP in the wound postinjury). Secondly, as diabetic skin lacking of SP due to extensive pathological changes of sensory ending, we make a hypothesis:one of the main reason of unhealing wounds on diabetic patients could be insufficient SP which lead to fewer ESCs recruitment around wounds.

在此基础上,为进一步验证P物质促进表皮干细胞向肉芽组织中募集这一重要发现,本研究首先利用β1整合素、K19、K15等干细胞标记物以及干细胞慢周期性的特点,分别在体观察了正常皮肤伤口愈合过程中SP组、辣椒素组采用特异性感觉神经毒性药物辣椒素(capsaicin皮下预注射化学性除去感觉神经从而阻止神经肽分泌、对照组肉芽组织中表皮干细胞分布特点;其次,糖尿病患者皮肤存在周围末梢神经的损伤和神经肽含量的下降,这是否会导致糖尿病皮肤伤口创缘表皮干细胞募集不足,继发伤口难愈?

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