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Autologous MSC can be obtained easily,their source in human are plenty , own active proliferationand potential to difference into chondroblast.

自体骨髓基质干细胞来源丰富,取材容易,具有旺盛的增殖能力及向成软骨细胞分化的潜能,已成为软骨组织工程的首选种子细胞,但MSC诱导分化为成软骨细胞且应用于软骨组织工程的技术尚不十分完善,目前主要采用的技术为细胞团块离心管培养,其构建的软骨组织在力学性能上很难达到关节软骨的要求。

Autologous MSC can be obtained easily, their source in human are plenty, own active proliferation and potential to difference into chondroblast. Now MSC become the chief seed-cell in cartilage tissue engineer, but the technology to stimulate MSC differentiate into chondroblast is not very successful, the standard technology is culture the cell-ball in centrifuge tube, the reconstructured cartilage-like tissue is not achieve the mechanics of hyaline cartilage.

自体骨髓基质干细胞来源丰富,取材容易,具有旺盛的增殖能力及向成软骨细胞分化的潜能,已成为软骨组织工程的首选种子细胞,但MSC诱导分化为成软骨细胞且应用于软骨组织工程的技术尚不十分完善,目前主要采用的技术为细胞团块离心管培养,其构建的软骨组织在力学性能上很难达到关节软骨的要求。

Autologous MSC can be obtained easily,their source in human are plenty , own active proliferationand potential to difference into chondroblast. Now MSC become the chief seed-cell in cartilage tissue engineer , but the technology to stimulate MSC differentiate into chondroblast is not very successful,,the standard technology is culture the cell-ball in centrifuge tube,the reconstructured cartilage-like tissue is not achieve the mechanics of hyaline cartilage.

自体骨髓基质干细胞来源丰富,取材容易,具有旺盛的增殖能力及向成软骨细胞分化的潜能,已成为软骨组织工程的首选种子细胞,但MSC诱导分化为成软骨细胞且应用于软骨组织工程的技术尚不十分完善,目前主要采用的技术为细胞团块离心管培养,其构建的软骨组织在力学性能上很难达到关节软骨的要求。

At an average follow-up of 34.3 months, using the Sports Ankle Rating System, the average clinical rating score was 96.2, the average quality-of-life measure was 96.7, and the average single assessment numeric evaluation was 95.3. Radiographs at final follow-up showed no mortise widening or lateral talar subluxation. Two patients had mild degenerative changes on lateral radiographs with anterior tibial osteophytes.

在平均34.3个月的随访中,用踝关节运动评估系统评分的平均得分是96.2,生活质量平均分是96.7,平均单个数字评估得分是95.3,在随访最后的X线片示没有踝关节关节间隙的变宽以及距骨的侧向半脱位。2个病人出现稍微的退行性变及胫骨前骨赘。

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