后生

Treatment of cisplatin-resistant cell lines with an inhibitor of DNA methyltransferases, 2-deoxy-5'azacytidine, results in partial reversal of DNA methylation, re-expression of epigenetically silenced genes including hMLH1 and sensitisation to cisplatin both in vitro and in vivo.

DNA甲基转移酶抑制剂2 -脱氧- 5'氮胞苷可部分逆转顺铂耐药细胞株的DNA甲基化，在体外和体内使后生沉默基因包括hMLH1基因重新表达并增加对顺铂的敏感性。

We have investigated whether the combination of decitabine and a clinically relevant inhibitor of histone deacetylase activity (belinostat, PXD101) can further increase the re-expression of genes epigenetically silenced by DNA methylation and enhance chemo-sensitisation in vivo at well-tolerated doses.

我们研究了地西他滨联合组蛋白去乙酰化酶抑制剂（belinostat，PXD101）是否可以进一步增加DNA甲基化后生沉默基因的重新表达，在耐受性良好的剂量下增加化疗敏感性。

Based on the achievements and developm ents in studying natural gas hydrates at home and abroad,the mechanism of causi ng the oil and gas reservoirs to be tightly sealed by the natural gas hydrates i s systematically analyzed in the paper through discussing the formation mechani sms,evolution properties and distribution laws of the natural gas hydrates.In li ght of the research on their control effects on petroleum accum ulation and reservoir preservation,several geologic models of oil and gas accumu lation and preservation related to the natural gas hydrates are proposed,such as vertically and laterally screened models,screened-by-drape and screened-by- contact models and syngenetically and epigenetically screened models,etc.

以国内外天然气水合物的研究成果和进展为基础，通过讨论天然气水合物的形成机制、演化特征以及其分布规律，系统分析了天然气水合物可以得天独厚地封盖油气藏的机理，探讨了其对油气藏尤其是气藏聚集和保存的控制作用，提出了天然气水合物聚集和保存油气的多类地质模式，如垂向遮挡和侧向遮挡、披覆遮挡和接触遮挡以及同生遮挡和后生遮挡等。

The topologic architecture of metazoan trace fossils may be subdivided into 3 clusters, 8 basic topologic configurations, 3 combined topologic configurations and 21 topoichnologic kinds, which are considered to be related to ethologic classifications of trace fossils in origin.

后生动物遗迹的拓扑结构可归并为3 族、8 种基本拓扑型、3 种组合拓扑型和21 种拓扑遗迹类，它们与习性类有较好的成因联系。

The infolding of a portion of the outer layer of a blastula in the formation of a gastrula.

外胚层囊胚的外层，在原肠胚形成之后生后外胚层组织

The gray and grayish green sandstones formed by hysterogenic reduction can be used as the lithogeochemical markers for exploration of uranium deposit.

由烃类流体产生的后生还原作用所形成的灰绿色砂岩可作为铀矿床的岩石地球化学勘查标志。

In the early days, Chinese came from China to settle here and they married the Malays.Their male descendants are called Babas,and their female descendants, Nonya

早期从中国南来的华人跟当地的土著女子结婚之后生下来的孩子的后代，男的叫峇峇，女的叫娘惹。

Texas and Ohio will not change the fact that Mrs Clinton has messed up what should have been an easy march to the nomination, allowing herself to be outcampaigned, outsmarted and outspent by a newcomer.

德俄两州的胜利所不能改变的一个事实是希拉里把原本早该结束的竞选弄成这步田地。无论是在竞选上，策略上还是花费上她都输给奥巴马这个后生晚辈一筹。

Here we demonstrate that DNA or RNA templates can orchestrate these genome rearrangements in Oxytricha, supporting an epigenetic model for sequence-dependent comparison between germline and somatic genomes.

在这里，我们证明的DNA或RNA模板可以协调这些基因组重排的oxytricha ，支持一后生模型序列依赖性比较胚和体基因组中。

Most importantly, we demonstrate that MBD association to methylated DNA seres to identify noel targets of epigenetic inactiation in human cancer.

更重要的是，与甲基化的DNA相关的MBD起到鉴定人类癌症后生失活新靶的作用。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务，你就做你的事好了。