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The typical apoptotic morphological features appeared in MUTZ1 cells treated with 4 mmol/L VPA for 72 hours. Pyknosis of cells and nuclei, disintegration of nuclear chromatin and apoptotic body could be observed by light microscopy. Aggregation and margination of nuclear chromatin, concentration of plasm, increment of density and chromatin mass of irregular size could be observed by transmission electronmicroscope. The flow cytometric analysis indicated that the VPA could induce cell apoptosis, apoptosis rate increased in dosedependent manner, ratio of cells at G0/G1 phase increased and ratio of cells at S phase decreased in dosedependent manner, the cells were arrested at G0/G1 phase.

结果显示: VPA对MUTZ1细胞的生长抑制作用呈现时间和剂量依赖性;经4 mmol/L VPA处理MUTZ1细胞72小时后,细胞呈现典型的凋亡形态特征,光学显微镜下可见凋亡细胞胞体固缩、核固缩、核碎裂及凋亡小体;透射电子显微镜下可见凋亡细胞核染色质边集、胞浆浓缩、密度增加,胞浆内大小不规则的染色质团块;流式细胞术结果表明,细胞凋亡率随着VPA浓度的增加而逐步增高,G0/G1期细胞比例随着VPA浓度的增加而逐渐增多,S期细胞比例逐渐减低,细胞被阻滞在G0/G1期。

The typical apoptotic morphological features appeared in MUTZ-1 cells treated with 4mmol/L VPA for 72hours. Pyknosis of cells and nuclei, disintegration of nuclear chromatin and apoptotic body could be observed by light microscopy. Aggregation and margination of nuclear chromatin, concentration of plasm, increment of density and chromatin mass of irregular size could be observed by transmission electronmicroscope. The flow cytometric analysis indicated that the VPA could induce cell apoptosis, apoptosis rate increased in dose-dependent manner, ratio of cells at G0/G1 phase increased and ratio of cells at S phase decreased in dose-dependent manner, the cells were arrested at G0/G1 phase.

结果显示:VPA对MUTZ-1细胞的生长抑制作用呈现时间和剂量依赖性;经4mmol/LVPA处理MUTZ-1细胞72小时后,细胞呈现典型的凋亡形态特征,光学显微镜下可见凋亡细胞胞体固缩、核固缩、核碎裂及凋亡小体;透射电子显微镜下可见凋亡细胞核染色质边集、胞浆浓缩、密度增加,胞装内大小不规则的染色质团块;流式细胞术结果表明,细胞凋亡率随着VPA浓度的增加而逐步增高,G0/G1期细胞比例随着VPA浓度的增加而逐渐增多,S期细胞比例逐渐减低,细胞被阻滞在G0/G1期。

Methyl methacrylate copolymer emulsion does better than the acrylic resin in improving the physical and mechanical properties.

添加改性剂MMA或AR后,浆体的流动性和浆体的强度得到了明显提高,其中MMA比AR在改善压浆材料的物理和力学性能方面更为显著。

On the basis,the numerical response to micromechanics of material microst...

在此基础上,利用有限元法对异质体材料微结构进行细观力学响应的数值计算,对于识别"材料结构弱点",评估微裂纹的启裂、扩展,预测异质体材料微结构材料损伤后的材料性能,推演"微结构虚拟失效"行为具有重要的意义。

Results: After a hundred thousand cycles of compression loads, the performing condition of small bone defect, parallel of a fin with force line, press fit implantation and three fins acetabular component fixed with three screws demonstrated a lest micromotion equaling 83 to 96 um.

结果:1、在压力负荷实验,经10万次加载686N压力载荷,采集100次、1000次、1万次、10万次假体微动位移,工况为小骨缺损面积—假体植入后翼与载荷力线平行—紧压配合植入—螺钉固定的三翼臼最为稳定,微动位移为83-96um,疲劳位移为151um。

Methods: Liver microsome was preparated from normal rat and human liver, which was to he treated with a series of concentrations of CsA or coadministration with Flu or MP. The activities of CYP3A in the microsomes were detected by using erythromycin as substrate.

製备大鼠和人肝微粒体,用不同浓度的CsA作用、加或不加MP、Flu,以红霉素为底物,经过NADPH系统孵育后,利用分光光度法测定人和大鼠肝微粒体的红霉素N-脱甲基酶活性。

This paper analyses and calculates the plow parameters about two kinds of high speed plows LEMKEN and KUHN, and studys the relation between the geometric parameters of shape of moldboard plow surface and soil properties, plowing quality, forces properties, plowing speed, resistance and energy dissipation during the plowing. Then according to the direction of developing high efficiency and saving-energy agriculture, under the premise of good farming quality this article puts forward a kind of method setting the mathematics model about plow resistance through the new cultivation principle and the new design principle.

本文通过对比分析的手段对LEMKEN和KUHN两种高速犁参数两种犁体曲面参数进行量化分析计算,分析犁体曲面形状的几何参数与耕后质量、土壤的力学特性、耕速、阻力和功率消耗等相关关系,结合目前高效节能型农业的发展方向,提出在保证作业质量的前提下,应用新型耕作理论和新型设计理论建立牵引阻力数学模型。

However, the formation of metal chelation at one or two side of biphenyl resulted a pair of enantiomers of monometallic or bimetallic complexes. Moreover, if the coordinating groups have chiral element (e.g., chiral oxazolines), the diastereomeric metal complexes will be formed.

而且,如果配位基团上带有手性元素,它们跟金属配位后得到一对非对映异构体,由于手性元素的影响,形成这一对非对映异构体的能量是有差异的。

The matrix of these samples was cast and then heated.Distinct interface between the matrix and mottle existed.

样品基体为铸态组织且铸后经过加热;斑纹与基体有明显的界面,斑纹是高锡的铜锡合金,厚度在20~40μm;斑纹主要是由SnO2与Cu41Sn11组成。

In this paper, the flax yarn will be used as the continuous reinforcement and the Polypropylene multifilament will be used as thermoplastic resin matrix. The two things will be made into a pp/flax covered yarn, which are ready to be woven into a plain fabric. The flax/pp composite board is accomplished by hot-pressing molding. Some other composite boards are also made, whose flax yarn haven been pretreated.

本课题将以亚麻纱线作为连续状增强体,聚丙烯复丝作为基体;采用包覆纱的浸渍工艺,制作了pp/亚麻包覆纱后浸料;再将包覆纱制成机织平纹布作为预成型件;通过热压成型工艺制作成复合材料板材;同时还制作了对亚麻纱线进行碱处理和偶联剂处理的复合材料板材。

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The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为:以确有疗效的中药复方为研究对象,以现代科学技术和传统中医药理论为技术支持,以该复方所治病证的药效响应为评价标准,以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。

I don't… don't know. He's unconscious.

我不……我不知道他休克了。