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RESULTSdiabetic rats showed typical symptoms involving elevated serum glucose and weight loss (2)The rats in DM+VaD group reacted slower and made more error numbers in Y-maze than the rats in VaD group did, with a prolonged total reacting time in a whole day.(3)More neurons with serious damages, such as edema, ischemia or pyknosis could be found in DM+VaD group than in VaD group. More disarrangement of cone neurons, obvious glia proliferation, and more neuron apoptosis were found in CA area of hippocampus. CONCLUSIONS (1)2-VO in STZ-induced diabetic rats succeeded in establishing VaD animal models.(2) The cognitive dysfunction induced by VaD rats had been deteriorated by diabetes mellitus.(3)Morphology evidences proved that diabetes mellitus aggravated brain damages induced by VaD.PART II Effect of diabetes mellitus on the cholinergic nervous systemin CA1 area of hippocampus of VaDOBJECTIVE To estimate the role of cholinergic nervous system in hippocampus during the process of cognitive dysfunction aggravated by diabetes mellitus in DM+VaD group. METHODS Observe the changes of ChAT protein by immunohistochemistry stain. Chose three rats randomly from each group at each pointat two week, four week, and eight week, then sepa

经腹腔注射链脲佐菌素诱导慢性实验性糖尿病,1周后永久性结扎双侧颈总动脉(2-VO)制作VaD模型记录术后2周、4周和8周各组大鼠的体重及血糖;应用Y-迷宫检测空间定向学第二军医大学博士论文中…丈摘…要1ia;一色恤~﹁染澎糕行HE染色观察组织病理学孪叱;胶质细胞原纤维酸性蛋白protellZ,Cf冰尸标记观察星形胶质细舱的激活情况、橄声软公点娜育票票众糯黑橄居端粗默孺篇筑价井袱第二部分糖尿病对血管性痴呆大鼠海马c心区胆碱能神经系统的影响探讨海马CAI区胆碱能神经系统在糖尿病加重确D一大鼠认知障碍中所实验动物及分组同第一部分,应用免疫组织化学染色方法现察海马CAI{介狱牛第晕军l袭拔常博粗{论义

It shows that the allantoin, which only takes little part in calves, was the main part (about73%~88%) in the cattle's urine, and the xanthine and hypoxanthine which are also take only much little part, can be neglected.

结果发现,试验牛尿中嘌呤衍生物中尿囊素大约为73%~88%,黄嘌呤和次黄嘌呤的含量很小,可以忽略不计,与以往对成年反刍动物的研究结果相似,与同个体犊牛期的研究结果相反。

The abounding allographemes and identicalness in Dongba characters are of great benefit to understand forepart morphophonetic scripts and provide consult to research on other national ancient scripts.

东巴文字是较为古老的一种意音文字,对其字素变体和同形现象的分析,有利于我们认识早期意音文字的特点,同时也可为其他民族古文字的研究提供参照。

The theoretical results of RMS radii and spin-parity values are in agreement with the experimental data.

理论计算的均方根半径和自旋宇称值与实验结果整体上符合较好,尤其是N=9同中子素中的2s1/2与1d5/2中子能级间的能级反转得到了较好的解释。

The primary theory of numbers aspect related integer property basic content.

摘要本论文主要讨论了整数的离散性、代数性质、有序性、整除性、最大公因数与最小公倍数、素因子分解、同余等初等数论方面的有关整数性质的基本内容。

Recombinant plasmid pSVH 7 DNA of avian influenza virus H7 subtype heamagglutinin gene was encapsulated with DC-chol/DOPE liposomes and PC/chol/SA liposomes separately. Two-week old SPF chickens were intramuscularly inoculated with 50 μ g/0.2ml of the liposome entrapped PSVH 7 DNA. Four-weeks later, each chicken was challenged with 0.1ml 〓 AIV . One week after the challenge, the secretion of the cloacas was collected and transfected to chicken embryos to isolate the virus. The virus was isolated from 6/6 of the control group, 1/6 of the naked DNA group, 1/6 of the PC/chol/SA entrapped DNA group and 0/6 of the DC-chol/DOPE liposome entrapped group. The HI antibody titers (log2) of the four groups were 6. 83±0.98, 7. 0±1. 26, 7. 83±1. 17 and 8. 00±0.89 respectively 1-week after challenge, and 8. 5±0.55, 8. 17±0.82, 8. 68±0.45 and 9. 33±0.54 respectively 2-week after challenge. The results showed that inoculation of liposome entrapped DNA significantly enhanced resistance to virosis in animals.

将含禽流感病毒H7亚型血凝素基因的重组质粒pSVH7用DC-chol阳离子脂质体和胆固醇/卵磷脂/十八胺脂质体包裹,免疫2周龄SPF鸡,4周后用同型禽流感病毒进行人工感染,1周后采集泄殖腔分泌物分离病毒,结果未免疫组6/6分离到病毒,裸质粒DNA免疫组1/6分离到病毒胆固醇/卵磷脂/十八胺脂质体包裹DNA免疫组1/6分离到病毒,DC-chol脂质体DNA免疫组没有分离到病毒(0/6):人工感染后1周各组的HI抗体(Log2)分别为6.38±0.98,7.00±1.26,7.83±1.17,8.00±0.89,2周后为8.50±0.55,8.67±0.82,8.68±0.45,9.33±0.52,脂质体包裹组在同期均高于未免疫组和裸DNA免疫组,表明脂质体包裹质粒DNA免疫动物后,能增加动物对病毒感染的抵抗力和反应能力。

36Cl and 36S particles were successfully separated in the TOF spectra from the GF-TOF detector for the ion with the energy of 64, 48 and 33 MeV, respectively. The comparison of the separation power of isobars between the GFTOF method and the ΔE-E method was carried out.

在不同能量(64、48和33MeV)下,利用充气飞行时间探测方法对同量异位素36S和36Cl进行鉴别,并与用传统的△E-E方法在相同能量下的鉴别结果进行比较。

After eliminating the isotopic backgrounds using the AMS technique, the isobars can be distinguished with their emitted characteristic X-rays when the projectile ions collide with target.

PX-AMS方法就是利用AMS技术排除同位素的干扰后,利用入射离子和特定靶材料碰撞时入射离子发射的特征X射线进行同量异位素鉴别。

Functional analyses demonstrated that adrenomedullin, a asodilatory hormone, synergized with stem cell factor and Flt-3 ligand to induce the proliferation of primitie human CD34+CD38–lin– cells and promoted the expansion of CD34+ progenitors in culture.

功能学分析显示肾上腺髓质素能够与干细胞因子及Flt-3配体协同作用从而促进原代培养的人CD34+CD38–lin–细胞增殖以及CD34祖细胞的扩增。

In order to solve the problem, we set up a method to simulate experimental spectra for medium-heavy nuclides in AMS measurements.

在AMS测量过程中的一个关键问题是排除同位素和同量异位素及其它本底的干扰。

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