同种移植

With the establishment of animal models of aortic homograft transplantation, using immunohistochemical staining, the difference of the expression of MHC Ⅰ antigen and MHC Ⅱ antigen was detected between fresh aortic homografts and cryopreserved ao rtic homografts.

建立大鼠同种异体主动脉移植模型，采用免疫组织化学实验研究新鲜主动脉和低温保存的主动脉同种异体移植后MHC Ⅰ类抗原和MHCⅡ类抗原表达的区别。

Objectives:(1) to introduce immunetolerance in mice sciatic nerve allograft by intrathymic injection of allogene.(2) to compare the effect of fresh sciatic nerve allotransplantion and cold preserved sciatic nerve allotransplantation with different diameter.

研究目的：(1)探讨小鼠胸腺内注射异基因抗原在同种异体异基因坐骨神经移植免疫耐受中的作用；(2)比较不同直径的新鲜自体神经和冷冻异体神经移植的效果，探讨神经直径对神经移植效果的影响。

The chronic GVHD of heterogenic marrow occurs at late stage and is rare,and it is not as typical as homogenic chronic GVHD in the clinical performance,and slighter than ho-mogenic GVHD in pathological process;there is no obvious difference between heterogenic and homogenic GVHD in the invaded region.

异种骨髓移植的慢性GVHD出现时间晚，较罕见，临床表现不如同种慢性GVHD典型，病变较同种GVHD轻；其病变侵犯器官与同种GVHD无明显区别。

The experiments may contribute not only to investigating the mechanism of interaction between ldiotype and anti -idiotype T cells by which immune network are up-regulated, but also to analysing the suppressive effect of anti -idiotypic T cell or antibodies against the antigens on the activated T cells in the allo-responsiveness.

本课题选用小鼠耳后心肌移植模型，用同种抗原特异的活化T淋巴细胞免疫同系小鼠的方法，诱导免疫小鼠同种心肌移植物存活时间的延长，以此探讨免疫网络中独特型-抗独特型相互作用机理，着重分析在同种抗原诱导的免疫应答中，抗独特型T细胞和抗活化T淋巴细胞抗原抗体对同种免疫反应的抑制作用。

Results:pedunculated omentum majus-cirded trachea transplantation ensured an early re-establishment of blood circulation of transplanted trachea and maintenance of its normal animate states; allogeneoilc transplantation of trachea activated bodys immune mechanism. resulting in a chronic process of rejection and finally leading to progressive necrosis of transplanted trachea tissues: chondroregeneration occurred at every period under perichondrium after transplantation. and the degree of regeneration was related with favorable blood circulation; the emplogyment of a supporting tube in trachea,under the condition of favorable re-establishment of early blood circulation, could preventgranulation tissue hyperplasia and keep trachea cavity unobstructed.Postgraduate Ding XiaoQuan Directed by-Lin LeShen

结果 带蒂大网膜包绕移植段气管行腹腔移植，早期重建了移植段气管的血液循环，保证了移植气管的早期成活及维持其正常生机状态；同种异体气管移植所激发机体的免疫机制，引起一个慢性排斥反应过程，导致移植段气管组织进行性坏死；软骨再生存在于移植后各个时间段，其再生程度与良好的血液循环有关；气管内支撑管的应用可防止肉芽组织增生堵塞管腔，从而保证气管管腔通畅。

All of the patients were divided into three groups,autologous bone graft in 21 cases,allogous bone graft in 23 cases, autologous bone mixed allogous bone graft in 27 cases. The fusion rate, the Cobb's angle loss rate of incidence and pseudoarthrosis were compared among the three groups at 3,9,15,36 months follow-up.

方法］ 回顾性分析2000年～2005年行后路钉-棒系统矫形手术的71例青少年特发性脊柱侧凸患者，其中自体骨移植21例，同种异体骨移植23例，自体骨混合同种异体骨移植27例，比较随访第3、9、15、36个月的融合率、Cobb's角丢失率及假关节发生率。

Corneal allograft is the most effective treatment for corneal blindness,but corneal graft rejective reaction is the main cause of corneal allograft. Corneal neovascularization is one of the most causes of corneal blindness and the high-risk factor of corneal graft rejective reaction.

研究背景同种异体角膜移植是治疗角膜盲最为有效的方法，而角膜移植排斥反应仍然是移植失败的主要原因；角膜新生血管是角膜盲的主要原因，亦是角膜移植排斥反应的高危因素。

Cases with renal transplantation were performed with dynamic state CDFIin Ultrasound Dept. of Nan fang Hospital from April, 2005 to October, 2006. Theexamine time is respectively after operation in three days, seven days, one month andthree months. Before operation examine the condition of uropoiesis function such as apair of kidney, ureter, bladder and cardiac function. After operation reexamine thecondition of cardiac function once again, and examine TK detailed and completely:First, using two-dimensional imaging to observe the shape and the volume of the TK.Secondly, using Color Doppler to observe the renal artery and each artery inside theTK. Finally, using pulsed Doppler to measure the peak systolic velocity, enddiastolic velocity and resistance index.

对南方医科大学南方医院超声诊断科自2005年4月～2006年10月对152例同种异体肾移植患者进行动态CDFI监测，超声检查时间分别为术前与术后3d、术后7d、1个月及术后3个月，术前超声检查双肾、输尿管、膀胱等泌尿系功能情况及心脏功能情况，肾移植术后再次对心脏功能情况进行跟踪复查，并对移植肾进行详尽检查：先用二维超声观察移植肾的形态、大小，随后应用CDFI观察移植肾动脉及肾内各级动脉的血流充盈情况，最后用脉冲式多普勒测量收缩期峰值流速、舒张末期流速、阻力指数。

Allogeneic and syngeneic fresh bone, autolyzed antigen-extracted bone, bone matrix gelatin, demineralized bone matrix were implanted into the muscle pouch of mice, at different times after implantation, the immunological, histological and alkaline phosphatase assay were conducted. The results revealed that all four kinds of allogeneic implants activated specific cellular and humoral immune responses, most notably in fresh bone group, the AAA, BMG and DBM inhibited the proliferation of the lymphocytes in vitro and BMG had the most powerful inhibiting action, allogeneic AAA, BMG and DBM might induce heterotopic osteogenesis in vivo, however, there were obvious difference in ALP and histomorphometry between allografts and isografts.

在小鼠肌肉内植入同种异体或同系新鲜骨、自消化抗原去除骨、骨基质明胶、脱钙骨基质，术后免疫学、碱性磷酸酶、组织学检查发现：4种同种异体植入物均可引发特异性细胞免疫反应和体液免疫反应，其中以新鲜骨移植引发的免疫反应最为显著；自消化抗原去除骨、骨基质明胶、脱钙骨基质在体外具有抑制淋巴细胞增殖的作用，骨基质明胶对淋巴细胞增殖的抑制作用最显著；同种异体与同系4种植入物在体内成骨活性有显著差异；自消化抗原去除骨、骨基质明胶、脱钙骨基质均有异位诱导成骨活性，其中骨基质明胶骨诱导活性最佳。

With the establishment of animal models of aortic homograft trans-plantation,using immunohistochemical staining,the differ-ence of the expression of MHCⅠantigen and MHCⅡanti-gen was detected between fresh aortic homografts and cryop-reserved aortic homografts.

建立大鼠同种异体主动脉移植模型，采用免疫组织化学实验研究新鲜主动脉和低温保存的主动脉同种异体移植后MHCⅠ类抗原和MHCⅡ类抗原表达的区别。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。