同种抗体

An antigen that stimulates the production of a particular agglutinin, such as an antibody .

同种抗体；同族抗体由与抗原相同的种类产生的或衍生的抗体，由它对该抗原作出反应

To characterize the isotype of human xenoreactive nat ural antibodies against porcine pancrease islet cells, cyostat sections of the p ancrease were incubated with the sera from 18 cases of IDDM or 20 human controls respectively, further with FITC-conjugated goat antihuman IgG or IgM secondary antibodies. IgG was found to bind to pancrease islet cells in sera from 8 cases of IDDM and 8 human controls, while IgM in 4 IDDM and 6 human controls.

为检测人抗猪胰岛细胞天然抗体的同种型，采取18份胰岛素依赖型糖尿病患者血清及20份正常人血清分别与杂种猪胰腺组织的冰冻切片孵化后，再用免疫荧光标记的羊抗人IgG、IgM单克隆抗体染色。8份IDDM血清和8份正常人血清中含有直接针对猪胰岛细胞的IgG型抗体；4份IDDM血清和6份正常人血清中含有IgM 型抗猪胰岛细胞抗体。

An isoantigen that on exposure to its corresponding isoantibody causes agglutination of the red blood cells to which it is attached.

同种凝集原；同族凝集原一个同种抗原，在接触它相应的同种抗体的会导致与其附在一起的红细胞发生凝集

We aimed to study the clinical importance of alloantibodies defined solely by solid phase techniques. METHODS.

我们该研究的目的在于明确固相技术单一检测同种抗体的临床重要性。

The experiments may contribute not only to investigating the mechanism of interaction between ldiotype and anti -idiotype T cells by which immune network are up-regulated, but also to analysing the suppressive effect of anti -idiotypic T cell or antibodies against the antigens on the activated T cells in the allo-responsiveness.

本课题选用小鼠耳后心肌移植模型，用同种抗原特异的活化T淋巴细胞免疫同系小鼠的方法，诱导免疫小鼠同种心肌移植物存活时间的延长，以此探讨免疫网络中独特型-抗独特型相互作用机理，着重分析在同种抗原诱导的免疫应答中，抗独特型T细胞和抗活化T淋巴细胞抗原抗体对同种免疫反应的抑制作用。

Methods Keratinocytes were isolated from the foreskins of children, and subjected to primary culture. The cultured keratinocytes were incubated with anti- keratin 16 antibody, or with isotype antibody as control, for various durations.

将抗角蛋白16抗体加入培养的角质形成细胞中，以同种型抗体作对照，研究外皮蛋白和Toll样受体2和4 mRNA表达。

Amiri and colleagues treated mice with a rabbit polyclonal antimouse anti-IgE or with an isotype control antibody and then infected them with S mansoni.

Amiri及其同事用兔抗多克隆抗IgE抗体或同种型对照抗体处理小鼠，然后使其感染曼氏血吸虫。

An antibody binding to IGF-IR and inhibiting the binding of IGF-I and IGF-II to IGF-IR which is characterized in that said antibody is a is ofIgG1 isotype, b shows a ratio of IC50 values of inhibition of the binding of IGF-I to IGF-IR to the inhibition of binding of IG-II to IGF-IR of 1:3 to 3:1, c inhibits for at least 80% at a concentration of 5 nM IGF-IR phospohrylation in a cellular phosphorylation assay using 3T3 cells providing 400,000 to 600,000 molecules IGF-IR per cell in a medium containing 0.5% heat inactivated fetal calf serum when compared to such an assay without said antibody, and d shows no IGF-IR stimulating activity measured as IGF-IR phophorylation at a concentration of 10 M in a cellular phosphorylation assay using 3T3 providing 400,000 to 600,000 molecules IGF-IR per cell in a medium containing 0,5% heat inactivated fetal calf serum when compared to such an assay without said antibody has improved properties in antitumor therapy.

一种已经提高了抗肿瘤治疗的特性的抗体，所述抗体结合IGF-IR并且抑制IGF-I和IGF-II与IGF-IR结合，其特征在于所述抗体a是IgG1同种型，b显示其对IGF-I与IGF-IR结合的抑制的IC 50 值与其对IGF-II与IGF-IR结合的抑制的IC 50 值的比率为1∶3-3∶1，c当与没有所述抗体的这种测定比较时，其在5nM的浓度上，在包含0.5％的热灭活胎牛血清的培养基中，使用3T3细胞的细胞磷酸化测定中，抑制至少80％的IGF-IR磷酸化，所述3T3细胞提供400，000-600，000分子IGF-IR/细胞，和d当与没有所述抗体的这种测定相比，在包含0.5％的热灭活胎牛血清的培养基中，使用3T3的细胞磷酸化测定中，其在10μM的浓度上没有显示作为IGF-IR磷酸化所测量的IGF-IR刺激活性，所述3T3提供400，000-600，000分子IGF-IR/细胞。

Induction of isotypic heterostrain antibody (Ab1): BALB/c mice were immunized with C57BL/6 splenocytes to raise antibody (Ab1) between the two difference strains.

抗同种异品系抗体(Ab1)的诱导 C57BL／6小鼠作为移植供体，BALB／c小鼠作为受体。取C57BL／6小鼠的脾细胞免疫BALB／c小鼠，制备抗同种异品系抗体(Ab1)。

It was suggested that isotypes of human xenoreative natural antibodies against porcine pancrease islet cells were IgG and IgM.

结果表明：人抗猪胰岛细胞天然抗体的同种型是IgG和IgM型抗体。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。