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Experiments on decalcification and activation of osteoinductive ability, comparison between the osteogenesis of demineralized bone matrix in orthotopic and in heterotopic sites, and correlation between immune response to allograft of bone and osteoinductive activity of the graft, were reported in this paper. 1. Syngeneic deminerolized bone matrix and the mixture of DBM with bone ash or acid-soluble protein extracted from demineralization was implanted into muscle pouch of mice, subsequently, the inhibition of DBM osteoinduction by bone ash or acid-soluble protein was demonstrated with histological and by means of alkaline phosphatase assay.

本文对脱钙处理使骨诱导活性表达的作用、脱钙骨基质植入不同部位的成骨表现,以及同种异体骨移植引发的免疫反应与骨诱导活性的内在关系三方面进行了研究:(1)在小鼠肌肉植入同系脱钙骨基质及其与脱钙所去除的骨矿盐和酸溶性蛋白混合物,碱性磷酸酶和组织学检查表明:骨矿盐和酸溶性蛋白具有抑制脱钙骨基质骨诱导活性的作用。

However, vascularized bone autograft can't provide suitable donor for big mass bone defect, large segment defect and bone defect with joint because of limitation of quantity, size, shape etc of donor. So, people thinks of vascaularized bone allogeneic transplantation .

不过,因受供体数量、规模、形体等因素的限制,对于大块、大段以及包括关节的骨缺损,带血供之自体骨移植,颇有力不从心之感,而同种异体骨移植的实行,似可提供一种新的、有效的手段。

The purpose of this study was to prospectively analyze the clinical outcome and graft morphology of patients who received fresh, hypothermically stored, allograft tissue for the treatment of symptomatic chondral and osteochondral defects of the knee.

这项研究的目的就是前瞻性分析接受用新鲜低温冻存的同种异体骨组织治疗有症状的膝关节软骨和骨软骨缺损的病人的临床疗效和移植物的形态学变化。

The two groups were compared for outcomes, including death, retransplant, nonfatal major adverse cardiac event, cardiac function, morbidity, and development of confirmed allograft vasculopathy.

两个样本组相较之下,厚度增加样本组的不良后果,包括致死、再移植、非致命性心脏病、心脏功能、病态,与被确诊的同种异体移植血管疾病的发展。

METHODS: Two groups of rats [allograft group and syngenic graft group] underwent limbal transplantation and healthy rats were taken as normal controls. The expression of RANTES and MCP 1 mRNA was detected by quantitative competitive RT PCR at post operative days 1, 3, 7, 11, 14, 21 and 30 and rejections were observed.

将大鼠随机分为同种异体移植组、自体移植组,并以健康大鼠作为正常对照组,用定量竞争性RT PCR的方法,在术后1, 4, 7, 11, 14, 21和30 d分别检测各组大鼠RANTES和MCP 1 mRNA的含量,并观察大鼠眼表变化,判断排斥反应的发生。

BACKGROUND: The reconstruction of allogeneic decalcified bone granules has been placed in the hot centre of material study. However, the ideal procedure remains need to be explored.

背景:同种异体脱钙颗粒骨的重构塑型是目前材料开发的热点研究,但至今仍未找到理想的方法。

OBJECTIVE: To observe the effect of the compound of calcium phosphate bone cement with allogeneic micromorselized bone on repairing bone defect at different ratios, and to determine the best ratio.

目的:观察不同比例的同种异体微小颗粒骨与磷酸钙骨水泥复合物修复兔桡骨缺损的效果,寻找最合适的比例。

Application of transplantation of cryopreserved vascularized bone allografts is an effective method for the treatment of massive bone defects in children, the clinical curative results of which is similar to that of transplantation of vascularized autografts.

对治疗儿童大块骨缺损,应用吻合血管的冷冻保存同种异体骨移植术是一种有效的方法,可取得类似于吻合血管的自体骨移植的治疗效果。

The compound vertebras reconstructed by allograft cortical bone cage and autogenous cancellous bone are ideal rebuilded materials for the instantaneous and permanent biomechanical stability.

同种异体皮质骨笼和自体松质骨组成的复合骨,即时和永久的生物力学稳定性均较好,是一种理想的椎体重建材料。

The successful implementation of the finger Replantation of various skin grafting, limb lengthening, and the retention of brain stem tumors of the facial nerve acoustic neuroma hysterectomy, kidney transplantation surgery, such as demanding attention by peers.

成功开展的断指再植术、各种皮瓣移植术、肢体延长术、脑干肿瘤及保留面神经的听神经瘤全切术、同种异体肾移植等高难度手术受到同行的瞩目。

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