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Failure of B cells to undergo immunoglobulin isotype switch in this case is a result of mutation on the CD40L gene in the activated T cells and B cells may have the ability to secrete IgG. This is the first case of HIGM with X-linked inheritance diagnosed at a molecular level in China.

患儿B细胞可能具有正常Ig分泌功能,Ig同种型转换障碍是由于其T细胞CD40L基因缺失,并在国内首次从分子水平上确诊一例性联高IgM综合征患儿。

A mouse model of POF was established by immunization injection of the ovarian antigen of isotype female mice on multiple subcutaneous sites and two posterior soles.

以BALB/c雌性小鼠卵巢组织制备卵巢抗原,皮下和两后脚掌多点注射免疫同种雌性小鼠建立卵巢早衰模型。

An antibody binding to IGF-IR and inhibiting the binding of IGF-I and IGF-II to IGF-IR which is characterized in that said antibody is a is ofIgG1 isotype, b shows a ratio of IC50 values of inhibition of the binding of IGF-I to IGF-IR to the inhibition of binding of IG-II to IGF-IR of 1:3 to 3:1, c inhibits for at least 80% at a concentration of 5 nM IGF-IR phospohrylation in a cellular phosphorylation assay using 3T3 cells providing 400,000 to 600,000 molecules IGF-IR per cell in a medium containing 0.5% heat inactivated fetal calf serum when compared to such an assay without said antibody, and d shows no IGF-IR stimulating activity measured as IGF-IR phophorylation at a concentration of 10 M in a cellular phosphorylation assay using 3T3 providing 400,000 to 600,000 molecules IGF-IR per cell in a medium containing 0,5% heat inactivated fetal calf serum when compared to such an assay without said antibody has improved properties in antitumor therapy.

一种已经提高了抗肿瘤治疗的特性的抗体,所述抗体结合IGF-IR并且抑制IGF-I和IGF-II与IGF-IR结合,其特征在于所述抗体a是IgG1同种型,b显示其对IGF-I与IGF-IR结合的抑制的IC 50 值与其对IGF-II与IGF-IR结合的抑制的IC 50 值的比率为1∶3-3∶1,c当与没有所述抗体的这种测定比较时,其在5nM的浓度上,在包含0.5%的热灭活胎牛血清的培养基中,使用3T3细胞的细胞磷酸化测定中,抑制至少80%的IGF-IR磷酸化,所述3T3细胞提供400,000-600,000分子IGF-IR/细胞,和d当与没有所述抗体的这种测定相比,在包含0.5%的热灭活胎牛血清的培养基中,使用3T3的细胞磷酸化测定中,其在10μM的浓度上没有显示作为IGF-IR磷酸化所测量的IGF-IR刺激活性,所述3T3提供400,000-600,000分子IGF-IR/细胞。

Karyorrhexis of osteocytes as well as loss of osteocytes in bone lacuna were detected in transplanted bone of control group,ultrastructure of osteocytes remained well in experimental group by transmission electron microscope.

我们在自行设计的吻合血管同种异体股骨干移植动物模型上建立了一套完善的检测指标,以证实供体在移植术后仍保持活力。

There are some differences in the numeral features (head diameter; Subcuticlar space), between the glandular hairs of the observed plants of Labiatae. The Index of the observed plants of Labiatae has been made with the above features and the types of the glandular hairs.

同种植物腺毛的数量特征(头部横径、角质层下间隙),也存在一定的差异,利用上述特征和腺毛类型,初步尝试性地建立了已观察唇形科植物的检索表。

In the development of probiotic products, different species of Lactobacilli and Bifidobacteria are selected according to their abilities to produce yogurt, to survive passage through the digestive tract, and to establish themselves in their new environment by outcompeting potentially unfriendly microbes for space and nutrients.

在开发&益生菌&产品的过程中,根据它们能制造酸奶的能力,人们选择不同种的乳酸杆菌素和双线菌素,想使它们通过消化道后仍然能够存活下来,并且在新的环境里,通过与可能有害的细菌争夺营养和空间得以立足。

This paper describes the study on intramedullary injection of fetal liver cell suspension into the lethally irradiated mice.

本文报告了用骨髓内注射法对8.5Gy照射的昆明种小鼠进行同种胎肝移植的结果,并与静脉内注射组进行比较。

The result fights allergic experiment to show, dispel the wind stops land of can different level restrains urticant Ding allergy of akin and passive skin mixes the bandicoot that antiserum causes 2, the sex of small rat late hair of chloric benzene be caused by exceeds 2 nitro- of 4- quick the thymus index that reaction; still can increase small rat when dosage greatly and lienal index; stop urticant experiment shows, dispel the wind stops urticant Ding can reduce the time of fit of small rat itching with dextrose lead anhydride and itching duration apparently, can increase Guinea pig to be able to bear or endure those who suffer phosphoric acid histamine send urticant threshold.

结果抗过敏试验显示,祛风止痒酊能不同程度地抑制抗血清诱发的大鼠同种被动皮肤过敏和2,4-二硝基氯苯所致的小鼠迟发性超敏反应;大剂量时还可增加小鼠的胸腺指数及脾指数;止痒试验显示,祛风止痒酊能明显降低右旋糖酐诱导的小鼠搔痒发作次数及搔痒持续时间,并能增加豚鼠耐受磷酸组胺的致痒阈。

Objective To study the clinical effect of cryopreserved allogeneic lunate bone transplantation on aseptic osteonecrosis.

目的 研究深低温冷冻同种异体月骨移植治疗月骨无菌性坏死的临床疗效。

Methods Cryopreserved allogeneic lunate bone transplantation was applied to 6 cases of aseptic lunate osteonecrosis who were followed up more than 10 years.

方法应用深低温冷冻同种异体月骨移植治疗月骨无菌性坏死6例,随访10年以上。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。