同基因的

Results as bellows: AtSIRT1 was located in Mitochondrial as hSIRT4 of human, and maybe take part in respiration and electron transformation chain, AtSIRT2 was located in nucleolus as hSIRT6 of human, maybe play important role in extend lifespan;mutation in AtSIRT1 leaded to cotyledon of plant turn to yellow and caused short life span. Mutation in AtSIRT2 could make the color of leaf turn to purple and accumulate a lot of anthocyanin;Sirtinol, a inhibitor of SIRT which did not cause the same model of the mutation of AtSIRT1 and AtSIRT2 indicated that the mechanism of Sirtinol was different from other organism;the structure of AtSIRT1 and AtSIRT2 were similar to other known Sir2, which indicated that they maybe have the same function;AtSIRT2 was overexpressed and its activity was detected.

结果表明，1，拟南芥AtSIRT1与人的同源蛋白hSIRT4相同，定位于线粒体，可能参与呼吸作用和电子传递，SIRT2与人的同源蛋白hSIRT6相同，定位于细胞核，可能同它的功能类似，在延缓衰老及调节细胞寿命方面起作用。2，AtSIRT1突变，可引起幼苗和植株的子叶变黄和早衰；AtSIRT2突变，可引起叶片发紫，沉积大量花青素。3，SIRT蛋白的抑制剂Sirtinol不能表型模写AtSIRT1和AtSIRT2突变体，说明Sirtinol在拟南芥中的作用机制不同于其他生物。4，AtSIRT1和AtSIRT2蛋白质结构预测表明与已知的Sir2蛋白相似，揭示其功能的相似性。5，在大肠杆菌中过量表达了其中一个基因(AtSIRT2)，可体外检测其酶学活性，进一步证明其功能。

Moreover, we illustrated the method by examining similarity or dissimilarity of exon-1 ofβ-globin gene of 11 species, and compared our results with some existing results of other methods.

以11种生物的β-globin基因的第一外显子为例分析了序列间的相似性，并同其它文献中的相似性分析的结果进行了比较。

Moreover, we illustrate these methods by examining dissimilarity of exon-1 of β-globin gene of 11 species, and compare our results with some existing numerical methods.

根据向量之间的欧氏距离，我们分析了11种生物的β-globin基因的第一外显子序列的相似性，并同其它文献中的相似性分析的结果进行了比较。

The expression absence of LRRC4 was ascribed to the loss of homozygosity of 7q32-ter in U251 cell lines. Conclusion The expression of LRRC4 gene is absent in glioblastoma cell lines, and it offers the important experiment proof for LRRC4 to act as a new candidate of brain tumor suppressor gene from glioma.

通过对胶质瘤细胞系基因组DNA中LRRC4的ORF序列的PCR扩增和测序分析，发现SF126，SF767，M17细胞中，ORF序列第279位氨基酸的第3个密码子存在同义点突变(3/5)，而U251和U87细胞基因组DNA中发生了LRRC4基因的缺失突变(2/5)。

Results These two patients were confirmed to suffer from DMD. They were characterized by typical features of DMD including typical clinical manifestations, increased serum enzymes, EMG presenting myogenic impairment, HE staining presentation belonging to DMD, negative dystrophin in brother, and inconstantly positive on the sarcolemma of sister. Furthermore, no deletion or duplication was found in the 1-79 exons of dystrophin gene. The suffering brother and sister carried the same maternal X chromosome.

结果 兄妹二人符合DMD诊断，具有典型的DMD临床表现，肌酸激酶、肌酸激酶同工酶、乳酸脱氢酶、羟丁酸脱氢酶和谷草转氨酶的水平均显著高于正常值，肌电图呈肌源性损害，肌肉HE染色符合DMD，男患者的抗肌萎缩蛋白表达阴性，女患者的少量肌纤维仍可见不连续膜阳性，两患者抗肌萎缩蛋白基因的1~79号外显子未见缺失和重复突变，女患者与男患者携带相同的母源性X染色体。

The liver oval cell line WB-F344 derives from adult normal Fisher 344 male rats. It's a kind of liver infantine epithelial cells and has characteristics of liver stem cells. Many studies in vitro and in vivo imply that it has the role as precursor cells of hepatocacinoma, which indicates its function in hepatocarcinogenesis.

肝卵圆细胞株WB-F344来自正常成年同基因Fisher344雄性大鼠，是一种肝脏幼稚上皮细胞，具有肝脏干细胞的性质，体内、外的许多研究表明，它与肝癌的发生有一定的关系，具有肝癌前体细胞的作用。

The liver oval cell line WB-F344 derives from adult normal Fisher 344 malerats.It's a kind of liver infantine epithelial cells and has characteristics of liver stemcells.Many studies in vitro and in vivo imply that it has the role as precursor cells ofhepatocacinoma,which indicates its function in hepatocarcinogenesis.

肝卵圆细胞株WB-F344来自正常成年同基因Fisher344雄性大鼠，是一种肝脏幼稚上皮细胞，具有肝脏干细胞的性质，体内、外的许多研究表明，它与肝癌的发生有一定的关系，具有肝癌前体细胞的作用。

The successful cloning of these isoenzyme genes of sea snake PLA2 may provide new information for the study on structure-function relationship of PLA2 family and its possible molecular mechanism.

这组海蛇PLA2同功酶基因的成功克隆为进一步揭示PLA2的结构与功能关系及可能的分子机制提供了新的信息。

Lamblia SUCH/89/BTMRI/2(C2) variant-specific surface antigen gene to that of sequence（TSA417） published in GenBank was 99% both at the nueleotide and the amino acid levels.

该表面变异抗原基因的核苷酸序列及推导的氨基酸序列同GenBank中Gillin发表的TSA417序列的同源性均高达99％。

Sequence analysis showed that the size of 16S rRNA gene was in 1235 bp, and lacking several regions which regarded as eukaryotic sequence, was more similar with prokaryotes than eukaryotes in sequence structural feature; it could be implied that the microsporidia had split from ancient eukaryotes very early in time on the phylogenetic tree.

序列分析表明，16SrRNA基因大小为1235bp，缺乏多个被认为是真核生物序列的区域，序列结构特征更多地类似于原核生物的，在进化上，推测微孢子虫在很早以前与原始真核生物产生分歧；分子进化分析发现，同属的微孢子虫可以处于系统进化树不同的分枝。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。