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In addition, our data indicated that the conformation of NR1 subunit homodimers was affected by the partner NR2 subunits during the formation of heteromeric receptor complexes, which might underlie the mechanism by which NR2 subunits modify NMDA receptor function. We also found that in the endoplasmic reticulum, even the whole extracellular N-terminal domain was truncated, the NR subunit could form homomers or heteromers with each other in HEK293 cells, which indicate that the NT is not the crucial element for the receptor assembly.

同时,通过推算FRmax,我们发现NR亚单位同二聚体的N端构象在形成功能性受体的前后是发生变化的,特别是对于NR1a亚单位,其同二聚体的N端构象会因与其配对的NR2亚单位的不同而发生不同的改变。

Finally,the following conclusions are gained.(1)The RF irradiation has effect on the relaxation course in a homonuclear system to some extent.(2)The...

研究结果表明:1射频场的照射对同核体系的弛豫有一定程度的影响。2 在射频场的照射下,同核体系的纵向弛豫时间T1 小于无射频场时的T1 ,而横向弛豫时间T2 大于无射频场时的T2 。3纵向弛豫时间T1 随射频场的增强而逐渐减小,横向弛豫时间T2 随射频场的增强而逐渐增大。

These compounds are of substantial interest both inviewpoints of theory and practical applications, mainlyunder the stimulus to achieve synthetic models either foractive sites of iron-sulfur proteins or for transitionmetal catalysts. This thesis describes the synthesis, structures andconformations of 51 new iron-sulfur cluster complexes,which have been characterized by elemental analysis andstandard spectroscopic methods. In addition, single-crystalX-ray diffraction analyses were performed for 4 representa-tive new compounds. Reactivities of μ-〓 with mono- and di- Grig-nard reagents derived intermediates toward various organicelectrophilic substrates were studied, along with complexa-tion of arynyl-containing iron-sulfur clusters by 〓Thus, several bridged, non-bridged, monomeric, dimeric,homonuclear, heteronuclear iron-sullfur and iron-sulfur co-balt-carbon cluster complexes were synthesized. A novelreaction and convenient route for the synthesis in highyield of tetranuclear iron complexes 〓 containing atetracoordinated sulfur atom was discovered, whereas aplausible mechanism based on experimental results was propo-sed for the formation of the new cluster type.

鉴于有机铁硫原子簇化学在基础理论发展和应用方面的重要意义,因此我们开展了这一课题的研究,并取得以下主要成果: 1、本文共合成了51个新有机铁硫及含钴碳簇基的有机铁硫原子簇配合物,除用元素分析,NMR,IR,MS法表征其结构和构象外,还用X-光衍射技术测得四个代表性配合物的单晶结构和构象; 2、我们业已发现炔基Grignard试剂同〓可形成一种&开环&与&闭环&中间物的平衡混合物,研究该平衡混合物同各种亲电试剂的反应; 3、研究发现了一种可高产率地形成〓含〓四配位硫挛合簇的新化学反应并对此反应提出了—种有趣的反应机理; 4、首次由1,4-二溴丁烷双Grignard试剂与〓制得一种新型铁硫簇双硫阴离子活性中间体,并进而研究了它的亲核反应性能; 5、找到了通过〓的光化学反应来合成簇合物〓-〓的一条有实用价值的新路线。

Serial types of important multiple-pluse NMRexperiments were analyzed: J-modulated spin-echo; polarization transfer; two-dimensional NMR spectra (NOESY,INADEQUATE,homonuclear COSY,heteronuclear COSY,SECSY,homonuclear J-resolved spectra,heteronuclear J-resolved spectra).

二维谱实验,分析了NOESY实验INADEQUATE实验、同核COSY实验、异核COSY实验、自旋回波相关谱SECSY实验、同核J分解谱实验和异核J分解谱实验(涉及质子反转门控去偶、FOCSY门控去偶和RE-FOCSY门控去偶四种实验)。

Compare to K type no.1B/1R male sterile line KTSP3314A,homotypic maintainer line TSP3314B and 1B/1R male sterile line K3314A,homotypic maintainer line 3314B at different developmental stages of superoxide dismutase,catalase,peroxidase activity and variety of malondialdehyde content.

利用K型非1B/1R类型小麦雄性不育系KTSP3314A,其同型保持系TSP3314B,以K型1B/1R类型小麦雄性不育系K3314A、其同型保持系3314B为对照,分别对其叶片和穗子在不同发育时期的超氧化物歧化酶、过氧化氢酶、过氧化物酶的活性和丙二醛含量的变化进行测定。

Results 5C11 induced homotypic aggregation, proliferation arrest and apoptosis in the multiple myeloma cell line XG2 highly expressed CD40. 5C11 induced B lymphoma cell line Daudi homotypic aggregation and proliferation arrest but no apoptosis.

结果 5C11能引起CD40表达强阳性的多发性骨髓瘤细胞XG2发生同型聚集,抑制其生长并介导细胞凋亡;5C11可引起CD40+的恶性B淋巴瘤细胞株Daudi发生同型聚集,抑制其生长并使细胞发生G2/M期阻滞,但并不介导细胞凋亡。

March 2008, already " introduction " La Shengli is opposite again Jiang Tao has his cousin " instructor ", will come in April between June, jiang Tao housekeep leased a building in Guilin city, bought much station computer, employ early or late more than 10 " man " eat to live together together; In April 2008, lasheng establishs church joist support of its wife's younger brother China how to handle 400 telephone calls, how to connect mobile phone He Xiaoling bind bilk undertakes on 400 number, will come in April between June, joist support China the person such as brother's son of its little brother, watch, fellow-townsman comes get together to and other places of Nanning, Guilin, do the line of business that had bilk of this one high-tech likewise.

2008年3月,已经&入门&的蓝胜立又对自己的表哥江滔进行&技术指导&,4月至6月间,江滔自立门户在桂林市租了房子,购买了多台电脑,先后雇用十余个&马仔&同吃同住;2008年4月,蓝胜立教会其小舅子梁承华如何办理400电话,如何把手机和小灵通捆绑在400号码上进行诈骗,4月至6月间,梁承华又纠集其弟弟、表侄、老乡等人来到南宁、桂林等地,同样干起了这一高科技诈骗的行当。

We, then, following the Holy Fathers, all with one consent, teach men to confess the one and same Son, our Lord Jesus Christ, the same perfect in Godhead and also perfect in manhood; truly God and truly man, of a reasonable soul and body; consubstantial with the Father according to the Godhead, and consubstantial to us according to the Manhood; in all things like unto us, without sin; begotten before all ages of the Father of the Father according to the Godhead, and in these latter days, for us and for our salvation, born of the Virgin Mary, the Mother of God, according to the Manhood; one and the same Christ, Son, Lord, Only-begotten, to be acknowledged in two natures, inconfusedly, unchangeably, indivisibly, inseparably; the distinction of natures by no means taken away by the union, but rather the property of each nature being preserved, and occuring in one Person and one Subsistance, not parted or divided into two persons, but one and the same Son, and only begotten, God the Word, the Lord Jesus Christ, as the prophets from the beginning concerning him, and the Lord Jesus Christ himself has taught us, and the Creed of the holy Fathers has handed down to us.

我们跟随圣教父,同心合意教人认识同一位子,我们的主耶稣基督,是神性完全、人性亦完全者;他真是上帝,也真是人,具有理性的灵魂,也具有身体;按神性说,他与父同体;按人性说,他与我们同体;在凡事上与我们一样,只是没有罪;按神性说,在万世之前,为父所生;按人性说,在晚进时日,为求拯救我们,由上帝之母,童女马利亚所生;是同一基督,是子,是主,是独生的,具有二性,不相混乱,不相交换,不能分开,不能离散;二性的区别不因联合而消失;各性的特点反得以保存,会合于一个位格,一个实质之内;而非分离成为两个位格,却是同一位子,独生的,道上帝,主耶稣基督;正如众先知论到他自始所宣讲的,主耶稣基督自己所教训我们的,诸圣教父的信经所传给我们的。

As a result, when in , subset of MA, obtained by imposing constraints on MA, AL is intensional because =L is equivalent with ≡.

在考虑了复制操作和限制操作的情况下,提出了逻辑等价的协归纳操作描述,并利用协归纳关系与进程结构同余关系进行比较,证明了若对MA加上约束条件得到子集MAsynIF,此时逻辑等价与结构同余关系是等价的,即AL在MAsynIF中是内涵的。

Results Preserving bilateral S1 anterior and posterior roots intact combined with rhizotomies of L7 and S2~3 posterior roots, intradural stimulation of S1 posterior root producedan increase of bladder and urethral pressure similar to that of stimulation of the S1 common root in extradural.

结果 保留2侧S1前后根完整,电刺激同平面S1的总根或后根,膀胱尿道的压力反应相同;切断两侧S1前根,刺激同平面的S1后根,膀胱尿道的压力反应显著降低,仅为前后根完整时的7%~12%。

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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。

This is not paper type of business,it's people business,with such huge money involved.

这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。