合成体

By following the "self-assisted molecular editing" protocol first established in our labs,a number of Aphos ligands were efficiently prepared from a single starting material and they were screened for catalytic efficacy, leading to the discovery of the best-performing Aphos appended with a 3-nitrophenyl group at the C4 position.Combination of this Aphos with Pd_2 offers a precatalyst for successful cross-coupling of unactivated aryl chlorides with aryl boronic acids at room temperature.The reactions took place under mild basic conditions to produce the products in high yields.

通过我们首次提出的&自助分子剪裁&的概念从单一起始物快速合成和筛选了一系列膦配体，并发现C4位含3-硝基苯基的的膦配体和醋酸钯联用可以在室温下顺利地催化不活泼氯代芳烃和芳基硼酸的偶联反应，反应条件温和且产物收率很高。

The infection of chlamydia trachomatis and ureal mycoplasma may be one of the factors, which cause the erosion of cervix.

沙眼衣原体和解脲支原体是引起宫颈糜烂的一种因素，宫颈糜烂合并 CT或 uu感染者治疗上应加用影响胞浆蛋白质合成的抗生素药物如阿奇霉素

Diltiazem is an important coronary vasodilating drug and contains two chiral centers while only the (2S, 3S)-isomer has the desired activity.

地尔硫卓是重要的心血管药物，在其分子结构中含有2个手性中心，可产生4个立体异构体，其中只有(2S， 3S)－异构体具有药理活性，因此其立体选择性合成具有很大的挑战性。

Under illumination condition,the ED50 and ED90 of direct virucidal activity of C60 to HSV-1F strain are 0.05313 μg/ml and 0.1696 μg/ml respectively,and the ED50 and ED90 of infection block action of C60 are 0.9461 μg/ml and 5.643 μg/ml separately.

以逆相蒸馏法合成了富勒烯脂质体，用药物对病毒所致细胞病变的抑制实验以及病毒的空斑减数实验，观察C60脂质体对HSV-1F株的直接杀灭、感染阻断及增殖抑制作用。

Methods We prepare the fullerene C60 liposomes using reversed phase distillation method,examine the direct virucidal activity,infection block and multiplication inhibition of C60 liposomes to HSV-1F strain,using inhibition experiment of cellular pathologic effect of virus and plaque reduction assay.

以逆相蒸馏法合成了富勒烯脂质体，用药物对病毒所致细胞病变的抑制实验以及病毒的空斑减数实验，观察C60脂质体对HSV-1F株的直接杀灭、感染阻断及增殖抑制作用。

These five zones are as follows: the zone of the reaction synthesis of TiC, the zone of reaction completion, the zone of the growth and homogenization of TiC, the zone of ideal structure and the zone of coarsened TiC particulates.

结果表明：适当提高合金熔体的等温反应温度并选择理想的反应时间，可获得尺寸细小、数目较多且分布均匀的原位TiC颗粒；当合金熔体中TiC的合成反应基本完成时，凝固速度对组织中TiC颗粒的数量和尺寸的影响不是很大。

The thiopeptides, by binding within a cleft located between the ribosomal protein L11 and helices 43 and 44 of the 23S rRNA, overlap with the position of domain V of EF-G, thus explaining how this class of drugs perturbs translation factor binding to the ribosome.

核糖体蛋白L11和23SrRNA的43/44螺旋结构形成裂隙，L11的构象变化能够加宽该裂隙从而允许延伸因子EF-G插入，促使GTP水解，为肽链延伸合成过程中核糖体的构象变化提供能量，而Thio能够与L11和23sRNA结合，阻止L11的构象变化，使该裂隙处于闭合状态，抑制EF－G在延伸过程中的作用。

Chiral SalanCrX complexesa saturated version of SalenCr(ⅢX are designed,and in conjunction with an ionic quaternary ammonium salt or organic strong base can efficiently catalyze the asymmetric,regio-and stereoselective alternating copolymerization of CO_2 with rac-PO at mild conditions to afford isotactic-enriched polycarbonates with～95%head-to-tail linkages and moderate enantioselectivity.

本论文在Salen构型配体的基础上，设计合成了一系列手性Salan型铬配合物，并将其与季铵盐/有机强碱组成亲电-亲核双组分催化体系，在室温下可以有效的催化CO_2和环氧丙烷的不对称交替共聚反应，实现了CO_2和环氧丙烷的不对称交替共聚反应的区域和立体化学控制，得到95%的头尾连接单元和中等光学纯度(对映体过量值ee%≈70%)的全同结构的聚碳酸酯。

To obtained useful chiral multi-substituted alkene-nitrile intermediates, the abnormal Beckmann rearrangement and their applications to the synthesis of the natural products were studied.

用甾体-17-酮肟的非正常Beckmann重排反应生成的相应的烯-腈化合物是合成18-去甲基甾体的重要中间体。

Zirconolite rich ceramics and Perovskite rich ceramics are fabricated for the incorporation of simulated trivalent actinide wastes, and the physical properties、XRD、SEM and durability tests are performed.

针对模拟三价锕系元素的固化，分别合成了富钙钛锆石固化体和富钙钛矿固化体，并对其主要性能进行了分析和比较，为其对三价锕系元素的固化提供了依

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失