合成体

Synthesis of Arylenealkyne Conjugated Macrocycles Containing Long Alkylene Bridge;2. Rigid,planar structures have been modified through incorporation of new additional groups to generate sharp-persistent imine macrocycles in very high yields.

我们设计并合成了一类氢键诱导下构象受限的芳酰胺寡聚体，以此模块作为前体，利用动态共价键的方法，高产率(80%-89%)地合成了一系列新的亚胺大环。

In the paper, the research evolvement of electrocarboxylation from carbon dioxide with olefin, alkyne, and ketones in near decades was summarized, these reactions were convenient ways to synthesize some valuable pharmaceutical precursor and intermediates in organic synthesis.

文章综述了近几十年来二氧化碳与烯烃化合物、炔烃化合物以及酮类化合物的电羰基化反应的研究进展，这些反应是合成一些有价值的药物前驱体或是有机合成中间体的简便方法。

In their structures, polyanions are bridged by Ln ions via the coordination of the bridging oxygen atoms and terminal oxygen atoms, forming a W–Ot′–Ln–Ob–W linkage; and through the W–Ot′–Ln–Ob–W linkage a one-dimension infinite linear chain with alternating cations and anions is formed.

在相似的合成条件下，我们向原有体系内加入顺丁烯二酸作为有机配体，合成了化合物7，其7的基本结构和化合物1-6很相似，但有一个顺丁烯二酸阴离子取代了一个NO3-离子的位置。

Based on the addition of vinyl magnesium bromide to the chiral non-racemic synthon 2 derived from-1, an enantioselective total synthesis of-3, the antipode of marine alkaloid halitulin 10 steps, overall yield: 5.3% from (R-1 was achieved using aza-Claisen rearrangement as a key step.

取得的主要结果如下：一、从-苯基甘氨醇1出发，通过已知的哌啶手性合成砌块2的加成反应，建立了经aza-Claisen重排反应进行海洋生物碱halitulin手性分子片断的对映体--isohaliclorensin 3不对称合成的路线。

Based on the addition of vinyl magnesium bromide to the chiral non-racemic synthon 2 derived from-1, an enantioselective total synthesis of-3, the antipode of marine alkaloid halitulin 10 steps, overall yield: 5.3% from (R-1 was achieved using aza-Claisen...

取得的主要结果如下：一、从-苯基甘氨醇1出发，通过已知的哌啶手性合成砌块2的加成反应，建立了经aza-Claisen重排反应进行海洋生物碱halitulin手性分子片断的对映体--isohaliclorensin 3不对称合成的路线。

These results suggest that the activate spleen-energy method can achieve appetitive purpose by not only affecting the gastrointestinal tract function in periphery, but also regulating the process of ingestion in brain. The basic research about ingestion indicate: one hand, after food enters the gastro-intestinal tract, the endocrine cell of the intestinal tract is activated and secrete many kinds of brains intestines peptide, the level of the brain intestines peptide in blood as the periphery signal spreads to the central nervous system regions that control digest and feeding behavior. On the other hand, it has been shown that dorsal parabranchial neurons, containing CCK-8S, extend fibers to the VMH and are involved in the inhibition of feeding .

关于摄食控制的基础研究表明，一方面食物进入胃肠道后，激活肠道的内分泌细胞，分泌多种脑肠肽如CCK-8S，这些脑肠肽在血中的水平作为外周信号可通过"肠—脑轴"传入中枢神经系统介导消化和摄食行为的部位，影响摄食中枢神经元的活动调节动物的摄食行为；另一方面中枢神经元可合成释放内源性的神经肽直接作用于摄食中枢神经元调节摄食，如中枢鳃旁体神经元的神经纤维就可延伸到达VMH，并且合成释放内源性的CCK-8S。

Some compounds possessing chiral center themselves may be racemates and appear racemic phenomenon in the extraction and separation from medicine herbs, structure modification and chemical synthesis.

但是，由于含有手性中心的中药有效成分本身可能是消旋体、或者在分离提取、结构改造及化学合成时会出现外消旋化现象，使新药研制与开发中面临对映体成分的分离制备、体内手性药物分析及对映体特异性药代动力学研究等重大难题。

Different from Ni70Mn25Co5（suitable for growing （100）crystal plate）, Fe is suitable for growing (111) crystal plate. It may be related to that (100)growing area of Fe is very narrow. In diamond research with medium of Fe, most crystals are octahedron or six-eight body. It is very hard to synthesize hexahedron diamond.

与Ni70Mn25Co5触媒生长特性（适合于（100）晶面生长）不同，Fe作触媒适合于（111）晶面生长，这可能跟Fe触媒的（100）生长区非常窄有关，因为在Fe触媒粉末金刚石研究中，晶体基本为八面体或六八面体，很难合成六面体金刚石。

A small, typically round, granular body composed of protein and RNA in the nucleus of a cell, usually associated with a specific chromosomal site and involved in ribosomal RNA synthesis and the formation of ribosomes.

核仁小而常为圆形的颗粒体，由蛋白质和细胞核中的核糖核酸构成，通常与一特定染色体缔合有直接关系并涉及核糖体核糖核酸的合成和核糖体的形成

The optimum conditions for this reaction were confirmed: the mole ratios of the Lewis base and AlCl〓 with the electron-rich aromatic monomer are 1. 2 and 3. 4, respectively; 1, 2-dichloride ethane is the most suitable solvent in this reaction; The solution of the two reactants must be added slowly to a large amount of solvent containing catalyst under pseudo-high dilution conditions; The Lewis base, such as NMP, DMF are applicable in this reaction system.

在此理论的指导下，通过对单体结构的模拟，高选择性地合成了一种新型结构的芳香环状聚硫酯二聚体，对其结构进行了精确的表征，在不同溶剂中得到了该环状二聚体的单晶，单晶X-ray衍射表明该二聚体为环张力极小的大环化合物。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失