合成代谢的

In the direction of the theory of metabolic engineering , principal nodes and their rigidity were judged, and metabolic flux distribution was regulated so as to overproduce FDP by chemical regulative factor.

在代谢工程理论的指导下判断了FDP合成途径中的结点和刚性结点，并用化学调节因子调节代谢流量的分配以超量生产FDP。

By the B vitamins pantothenic acid to be part of a coenzyme, by thiol molecules with the acid or other organic acids acyl combined into a acetyl or another acyl-carrier involved in a variety of acyl synthesis and catabolism It is an important acyl coenzyme metabolism.

由B族维生素泛酸参与组成的一种辅酶，借分子中的巯基与乙酸或其他有机酸的酰基结合，成为一种乙酰基或另一些酰基的载体，参与酰基的各种合成和分解代谢，是酰基代谢中重要的辅酶。

It contents with uracil in the same enzyme system,blocks the metabolic link,impeds the synthesis of DNA,and then prohibits the propagation of the cancer cells.

它的结构与肿瘤细胞所必需的代谢结构尿嘧啶相类似，在同一系统酶中互相竞争，阻断代谢环节，阻碍DNA的合成，从而抑制肿瘤细胞的增殖。

They were thought involved in anthocyanidin biosynthesis in light-sensitive "Tsuda" and light-insensitive "Yurugi Akamaru". Reverse subtractions, i.e., library 1 and library 3, were compared.

比较反向构建的消减文库1和3发现，在消减文库1中筛选到的基因片段涉及54条代谢途径，其中包括类黄酮生物合成等特异的代谢途径。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变，则将导致关节软骨基质成分的丢失和进行性破坏；软骨细胞凋亡与OA的发病密切相关，Fas与NO可各自独立介导软骨细胞凋亡，造成关节软骨破坏；IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子，具有促进细胞生长、增殖与合成等作用，可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用，可促进软骨细胞增殖、分化与蛋白多糖的合成，具有较强的诱导软骨形成的能力，研究表明多种生长因子相互促进、相互抑制，以协同或拮抗方式影响软骨细胞代谢，影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

Grace Slim-cellulose capsule Breakthrough tradition thin body concept, Creates the thin body new times,Grace Slim-cellulose capsule Take the traditional keeping in good health idea as the basis, Union modern science metabolism balanced theory, Selects: Aloe distill, Spore farina, Spirulina powder, Vitamin, Chitin, The pure medicine food homology plant fine becomes, It includes the many kinds of amino acids, Vitamin, Meals cellulose, Human body essential trace element, Through slows down the fat synthesis, Balanced nutrition metabolism, Acceleration Steatolysis, Continues moderately to reduce the fat

雅姿丹塑形纤维素突破传统瘦身概念，创造瘦身新时代，雅姿丹塑形纤维素以传统养生理念为依据，结合现代科学的代谢平衡理论，选用芦荟提取物，灵芝孢子粉，螺旋藻，维生素，甲壳等纯正药食同源植物精致而成，。它含有多种氨基酸，，维生素，膳食纤维素及人体必需的微量元素，通过减缓脂肪合成，平衡营养代谢，加速脂肪分解，持续适度地减少脂肪。

In order to overcome some of the disadvantages of plant cell suspension culture, such as variability and shear sensitivity of plant cells, limited transfer of oxygen to the culture, mixing and relative low metabolites production, etc.

本文针对悬浮细胞培养中植物细胞剪切敏感性、溶氧及混合困难和次生代谢产物合成能力低等问题，进行固定化长春花植物细胞培养生产生物碱过程的研究，主要涉及固定化方法、影响固定化长春花植物细胞合成生物碱能力因素、及有关固定化长春花植物细胞反应器等问题，应用模糊集理论探讨固定化细胞培养过程的基本规律。

Artificial conditions of plant cell culture, such as plant growth regulators, nutritious factors and elicitors, can be as metabolic regulation signals to regulate plant cell growth and secondary metabolite biosynthesize.

植物细胞培养的人工环境中诸如植物生长调节剂、营养因子和刺激剂等代谢控制信号可以调节控制植物细胞生长和次级代谢产物的生物合成。

For long-term treatments, the rat administered daily by gavages for six weeks, the results of OGTT showed that guava fruit water or alcohol extracts could reduce the plasma glucose level in the diabetic Wistar rats, however there was on significant difference in insulin level among all tested groups. The results of carbohydrate metabolism showed diabetic Wistar rats administered with 200 or 400 mg/kg BW of guava fruit water or alcohol extracts could decrease more than 15% glucose-6-phosphatase and fructose-1,6-bisphosphatase activities, and it also increase more than 12% glucose-6-phosphate dehydrogenase activities to reduce inhibitory hexokinase from reducing glucose-6-phosphate level.

在醣类代谢方面，实验结果发现糖尿病鼠灌食番石榴果实水及乙醇萃取物六周后，肝脏醣质新生作用中丙酮酸合成肝醣之关键酵素glucose-6-phosphatase及fructose-1，6-bisphosphatase的酵素活性会降低15%以上；另一方面肝脏glucose-6-phosphate dehydrogenase酵素活性则明显增加12%以上，并造成glucose-6-phosphate浓度减少，进而降低其对hexokinase的抑制(因为hexokinase受其代谢产物G-6-P的浓抑制)，因此加速肝脏葡萄糖的糖解作用。

The chip used contains 4097 genes covering oncogenes and tumor suppressor genes, the genes related to ion channels, cell cycle proteins, outer force reaction proteins, cell skeleton and movement, and apoptosis, the genes associated with DNA synthesis, repair and recombination, the genes related to DNA combining and transcription, the genes encoding cell receptors, the genes related to signaling, the genes associated with immune response, metabolism, protein synthesis, development and others.

实验所用的芯片含有4097个基因，包括原癌基因和抑癌基因、离子通道和运输蛋白基因、细胞周期蛋白基因、外压反应蛋白基因、细胞骨架蛋白和运动相关基因、细胞凋亡相关蛋白基因、DNA合成和修复和重组相关蛋白基因、DNA结合和转录和转录因子基因、细胞受体基因、免疫相关基因、细胞信号传导蛋白基因、代谢相关蛋白基因、蛋白质翻译和合成相关基因、发育相关基因、及其它基因。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失