合成

the target compounds synthesized to synthesize a series after 4 - instead of aniline - 6 -(2 - hydroxyl replace c oxygen radicals) quinazoline compounds has laid a good foundation.

目标化合物的顺利合成为以后合成一系列4-取代苯胺-6-(2-羟基取代丙氧基)喹唑啉类化合物奠定了良好的基础。

The goal of the successful synthesis of compounds for the subsequent synthesis of a series of 4 - to replace the aniline -6 -(2 - hydroxy replace C oxy) quinazoline compounds laid a good foundation.

目标化合物的顺利合成为以后合成一系列4-取代苯胺-6-(2-羟基取代丙氧基)喹唑啉类化合物奠定了良好的基础。

The five quinazoline compounds were prepared by using 2????amino????4,5????dimethoxy benzoic acid as original material, which underwent ring????

我们改进了这种化合物的合成方法，用简单省时的SOCl2回流法合成五种喹唑啉类EGFR？？？？

The biosynthesis of the quinoid nucleus are the same in all coenzyme Qs. The biosynthesis of the isoprenoid side chain determine the kind of coenzyme Q.

芳香环的合成在所有的辅酶Q族物质中都是相同的，异戊烯基侧链的长度则决定了辅酶Q的种类，这里存在一个关键酶，即异戊烯焦磷酸合成酶。

Methods Using 4-chloro-2-nitroaniline as a starting compound, followed by substitution, reductive cyclization, oxidation, and chlorination, to give the key intermediate 2,7-dichloroquinoxaline (7), which reacted with different phenolic compounds to afford quinoxaline derivatives.

方法以4氯2硝基苯胺为起始原料经取代、还原关环、氧化、和氯代合成了中间体2，7二氯喹喔啉(7)，再在喹喔啉的2位引入不同的取代酚结构单元，合成了一系列共9个新喹喔啉衍生物。

We focused the study on the synthesis methods of quinoxaline, nitration of its aromatic ring and chlorination of its heterocycle. In this paper, we thought about environmental protection, the cost of material, the feasibility of industrialization, workup easily, and obtained 2,3(1H,4H)-quinoxalinedion, 6-nitro-2,3(1H,4H)-quinoxalinedion, 6,7-dinitro-2,3(1H,4H)–quinoxalinedion, 2,3-dichlo- roquinoxaline, 6–nitro-2,3-dichloroquinoxaline,and 6,7- initro-2,3-dichloro-quinoxaline. A more reasonable, easily, efficient and simple reactive route to synthesize above-mentioned compounds was developed by systematically investigating the yield, the purity and physical character of intermediates.

本文针对喹喔啉及其芳环硝化、杂环氯代的合成进行研究，主要考虑了环保性、原料成本、产业化的可行性、反应操作的简便性等问题，获得了2，3(1H，4H)-喹喔啉二酮、6-硝基-2，3(1H，4H)-喹喔啉二酮、6，7-二硝基-2，3(1H，4H)-喹喔啉二酮、2，3-二氯喹喔啉、6-硝基-2，3-二氯喹喔啉和6，7-二硝基-2，3-二氯喹喔啉等六个中间体，考察了反应产物的产率、纯度和性状等因素，得到了更为合理、方便、实用、简洁的可供产业化的合成路线。

Benzyloxy benzoyldimethylsulfoxide was prepared by the reaction of ethyl 4-benzyloxybenzoate and dimethyl sulfoxide in the presence of sodium hydride, followed by Pummerer reaction with concentrated hydrochloric acid to afford eo-hydroxy-co-thio-methyl-(4/-benzyloxy) acetophenone, which reacted with urea, thiosemicarbazide, semicarbazide hydrochloride and o-phenylenediamine to give imidazolidine-2,4-dione, l,2,4-triazine-3- one and quinoxaline derivatives, respectively.

本文用4-苄氧基苯甲酸乙酯和二甲亚砜为原料，在氢化钠存在下反应，合成了(4′-苄氧基)-苯甲酰基-二甲亚砜。研究了该亚砜在浓盐酸的存在下发生的Pummerer重排反应，用重排产物ω-羟基-ω-甲硫基-(4′-苄氧基)-苯乙酮分别与尿素、氨基脲、氨基硫脲和邻苯二胺反应合成了2，4-咪唑啉-二酮、1，2，4-三嗪-3-酮、喹喔啉等含氮杂环化合物。

Quinoxaline; thiophene; heterocycle ; conjugated polymers; electrochemical synthesis; solid-state phase reaction synthesis

工程科技I，化学，高分子化学喹喔啉；噻吩；杂环；共轭聚合物；电化学合成；固相合成

Chiral aminoalcohol is an important kind of chiral substance in the asymmetric synthesis, meanwhile, it is widely used in the field of medicine synthesis and the resolution of raceme.

手性氨基醇在不对称合成领域中是一类重要的手性源，同时，手性氨基醇在药物合成、外消旋体拆分等领域也具有广泛的用途。

It was pointed out that the major difference in all the routes was the adjustment in the synthesis of intermediates: 1 racemization of-intemediate; 2 asymmetric synthesis of-intermediate, 3 the preparation of duloxetine from-intermediate.

指出所有这些路线的主要的区别在于调整了中间体的合成方法：将不能利用的-中间体消旋，手性合成-中间体，-中间体制备盐酸度洛西汀。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失