叶酸

Drugs and toxic agent s may interferewith the appropriate utilization of folic acid andcause a megaloblastic anemia.

药物与毒物在适当利用叶酸时，而可能引起巨成红细胞性贫血。

Megaloblastic anaemia (the red cells are megablastic ie large and abnormal) develops if vitamin B12 or folic acid are lacking.

巨贫血（红血球是megablastic即大和不正常的）发展，如果维生素B12或叶酸缺乏。

We measured the serum sFR and membrane-associated FR ofmorrow cell on megaloblastic anemia,MDS and leukimia,and RBC folic acidwith radio-receptor assay in same time.

本实验应用放射受体技术检测了巨幼细胞贫血、MDS及白血病患者血清sFR和骨髓细胞膜FR水平，同时检测了这些患者红细胞内叶酸水平。

Neomycin on ammonia acid can lead to vitamin B12 deficiency; phenytoin, methotrexate, B ammonia pyrimidine, methyl benzyl ammonium pyrimidine and Triamterene, etc. can cause folic acid deficiency; mercaptopurine, 5 - fluoro-piperidine urine density, Ara-C, etc. can interfere with nucleic acid synthesis, these drugs can lead to megaloblastic anemia.

新霉素、对氨水杨酸可导致维生素B12缺乏；苯妥英钠、甲氨蝶呤、乙氨嘧啶、甲基苄氨嘧啶及氨苯蝶啶等可引起叶酸缺乏；巯嘌呤、5--氟尿密啶、阿糖胞苷等能够干扰核酸的合成，这些药物都可导致巨幼红细胞性贫血。

The results demonstrated the eleuation of sFR and FR in the patientswith megaloblastic anemia and leukemia,and the depression of sFR and FRin the patients with MDS.

MDS组血清sFR，骨髓细胞FR均明显低于正常对照组，其红细胞叶酸水平亦低于正常对照组。

Yelodysplastic syndromes,as a disease of dyspoiestichematopoietic stem cell,have a disturbance of DNA synthesis,cellsdifferentiation and some leudemic characterization.It's marrow cell displaylike megaloblastic change,so we postulated that folate receptor have adifference of both quantitative and quanlititive in megalolbastic anemia,MDSand lenkemia.

DS作为异常干细胞克隆性增生疾病，在DNA的合成及细胞分化异常，表现出白血病的某些特征和骨髓细胞具有不同程度的巨幼变，因而我们推测巨幼贫、白血病和MDS的叶酸受体不但有量的改变，而且有质的变化。

Used with caution in pregnant women. 2, estrogen medication during early pregnancy can cause fetal hydrocephalus, cerebral meningocele, visceral malformations, feminization of male fetus, testicular dysplasia, low reproductive capacity, pregnant women忌用. 3, pregnant women taking high-dose folic acid may be a high concentration of zinc metabolism in pregnant women do together which led to scattered and intrauterine fetal growth retardation and low birth infants rationale. 4, a cold fever of 39 degrees sustained for more than 24 hours can cause fetal facial malformations such as lip.

孕妇慎用。2、雌激素妊娠早期用药可致胎儿脑积水，脑脊膜膨出、内脏畸形，男胎女性化，睾丸发育不良，生殖能力低下，孕妇忌用。3、孕妇服用大剂量高浓度叶酸可干拢孕妇锌代谢而导致胎错落和宫内发育迟缓和低出生体理儿。4、感冒发热达39度以上持续24小时以上可引起胎儿面部畸形如兔唇。

Pregnant women, lack of folic acid can cause fetal neural tube defects such as spina bifida, spinal Meningocele, no brains infants, microcephaly, hydrocephalus.

孕妇缺乏叶酸可引起胎儿神经管畸形，如脊柱裂、脊脑膜膨出、无脑儿、小头畸形、脑积水。

In a population of 11,770 NHANES participants from 1999 through 2004 who were 4 to 19 years old, the investigators looked at the relationship of headache with BMI; CRP; homocysteine levels; serum and red blood cell folate levels; vitamin B12; methylmalonic acid levels; total cholesterol, high-density lipoprotein cholesterol, and non-HDL cholesterol levels; triglyceride levels; uric acid levels; and platelet count.

在1999年到2004年之间，共有11，770位NHANES参与者，参与者的年龄介于4~19岁，研究者研究头痛与BMI、CRP、同半胱胺酸浓度；血清与红血球叶酸浓度；维生素B12；甲基丙二酸；总胆固醇、高密度脂蛋白、以及非HDL胆固醇浓度；三酸甘油脂浓度；尿酸浓度与血小板数目。

In a population of 11,770 NHANES participants from 1999 through 2004 who were 4 to 19 years old, the investigators looked at the relationship of headache with BMI; CRP; homocysteine levels; serum and red blood cell folate levels; vitamin B12; methylmalonic acid levels; total cholesterol, high-density lipoprotein cholesterol, and non-HDL cholesterol levels; triglyceride levels; uric acid levels; and platelet count.

在1999年到2004年之间，共有11，770位NHANES参与者，参与者的年龄介於4~19岁，研究者研究头痛与BMI、CRP、同半胱胺酸浓度；血清与红血球叶酸浓度；维生素B12；甲基丙二酸；总胆固醇、高密度脂蛋白、以及非HDL胆固醇浓度；三酸甘油脂浓度；尿酸浓度与血小板数目。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。