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W by hypodermic in each group,the effect and adverse reaction in each group on renal anemia were observed and compared.results the anemia of each group was improved after treatment.hb,hct and tast in venous group significantly increased than those of oral group,while incidence of adverse reaction decreased as compared to oral group.conclusion fe3 dextran that aid for rhuepo is better than oral group (p.01),and incidence of adverse reaction is lower,thus it is a better way that adds chalybeate to hd patients which is short of iron.

w皮下注射。比较两组患者贫血治疗的效果和副作用。结果治疗后两组患者贫血均改善,其中静脉补铁组的hb、hct及tast较口服补铁组显著升高(p.01),而不良反应发生率较口服补铁组降低。结论静脉注射右旋糖酐氢氧化铁可作为血透伴缺铁患者更理想补铁方式,配合rhuepo治疗贫血,疗效明显优于口服补铁,且不良反应发生率低。[关键词]右旋糖酐氢氧化铁;肾性贫血;血液透析

ConclusionA highiron animal model can be established by intraperitoneal injection of iron dextran. The changes of various parameters result in damage to the organs, it is possible that the ferri ions were released through metabolism of iron dextran and freeion mediates lipid peroxidation to cause the damage.

给小鼠腹腔注射右旋糖酐铁,可以成功建立高铁动物模型,其各项指标有明显变化并对各脏器造成损害,其机制可能与右旋糖酐铁在体内代谢释放出铁离子,游离的铁离子介导脂质过氧化而造成的损害等有关。

ConclusionA highiron animal model can be established by intraperitoneal injection of iron dextran. The changes of various parameters result in damage to the organs, it is possible that the ferri ions were released through metabolism of iron dextran and freeion mediates lipid peroxidation to cause the damage.[KEY WORDS]IronDextran complex; Models, animal; Lipid peroxidation

给小鼠腹腔注射右旋糖酐铁,可以成功建立高铁动物模型,其各项指标有明显变化并对各脏器造成损害,其机制可能与右旋糖酐铁在体内代谢释放出铁离子,游离的铁离子介导脂质过氧化而造成的损害等有关。

SAP patients were rando nly divided into the treatment group(n = 62) receiving mass fluid replace and intravenous intromission anisodamine 20mg and low molecular dextran 500ml per day, and the control group (n = 60) receiving intravenous octreotide (0.25mg/h) as a routine treatme nt.

探讨大量补液,同时应用低分子右旋糖酐和山莨菪碱治疗重症急性胰腺炎的疗效。122例确诊急性胰腺炎的患者随机分为两组,治疗组(n=62)在中心静脉压监测下大量补液,同时应用低分子右旋糖酐500ml加入654-2 20mg静滴,每日一次。

Molecular weight dextran sulfate is a very low molecular weight dextran by sulfonation from 1500, this drug is also currently the world's AIDS drug, one of the best.

分子量为3000的右旋糖酐硫酸酯,是通过对极低分子量右旋糖酐1500磺化而成,这种药物也是目前世界上防治爱滋病效果最好的药物之一。

Objective To investigate the effect of hypertonic saline/dextran 70 on delayed resuscitation of burn shock. Methods Eighteen mongrel dogs with 35% TBSA,third-degree burn were used in this study.

目的 从血流动力学、心肌力学及代谢等方面探讨高张氯化钠右旋糖酐液(7.5%氯化钠+6%右旋糖酐70,HSD)在烧伤休克延迟复苏中的作用。

Methods Eighteen mongrel dogs with 35% TBSA,third-degree burn were used in this study.Lactated Ringer's or 7.5% NaCl+6% dextran 70 was given for resuscitation 6h postburn.

目的 从血流动力学、心肌力学及代谢等方面探讨高张氯化钠右旋糖酐液(7.5%氯化钠+6%右旋糖酐70,HSD)在烧伤休克延迟复苏中的作用。

The existence of dextran sulphate to the native ovalbumin leads to decrease about 60% in fluorescence intensity following high pressure treatment. Complexation of polysaccharide with ovalbumin seems to protect the protein against pressure induced conformational change and aggregation; The presence of τ-carrageenan in glycinin solution is also found to protect the protein against pressure.

经超高压处理后,加入硫酸右旋糖苷的鸡蛋清蛋白溶液中的ANS荧光强度显著降低,降低约60%;这表明,硫酸右旋糖苷的加入可以和鸡蛋清蛋白相互作用,从而在超高压处理中起到稳定蛋白质天然构象的作用;对于大豆豆球蛋白溶液而言,ι-角叉菜胶的加入有维持高压下大豆豆球蛋白构象稳定性的作用。

Circular dichroism spectroscopy measurements also reveal that the ordered structure content of α-helical and β-structure of ovalbumin decrease, and the unfolded random structure is enhanced with increasing pressure; While the existence of dextran sulphate to the native ovalbumin, there are no apparent change on the secondary structure of ovalbumin; It seems same to glycinin.

圆二色性光谱分析表明,经超高压处理后,鸡蛋清蛋白分子中规则的二级结构减少,而部分规则的二级结构和无规卷曲含量增加。加入硫酸右旋糖苷的鸡蛋清蛋白溶液经超高压处理后其二级结构中各部分的含量变化不大:对于大豆豆球蛋白,加入硫酸右旋糖苷后,大豆豆球蛋白分子经超高压处理后其有序结构的减少及无规卷曲的增加都相对减缓。

The process and condition in the preparation of dextran through the fermentation of Leuconostoc mesenteriodes 0326 were discussed in the paper.The adhesive viscosity,pH value, the production of fructose and dextran,variation of molecular weight and the fermentation inducer were investigated,and the related curves of the dextran fermentation presented.

文章对由肠膜状明串珠菌L.M0326发酵生产右旋糖酐的工艺过程及条件进行了探讨,通过对其发酵过程中的粘度、pH值、果糖、右旋糖酐生成和分子量变化的研究及对发酵诱导物的考察,得到了右旋糖酐发酵工艺的相关工程曲线。

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