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In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响,结果表明SY-801和SY-640体内连续给药3天,可诱导小鼠肝微粒体细胞色素P-450含量明显增加,同时氨基比林脱甲基酶活性亦明显增加;给药1次2小时内二者均可抑制氨基比林脱甲基酶活性,而对肝微粒体细胞色素P-450含量则无明显影响。

The low dose of sodium arsenite can induce the hormesis of cell survive and MT production.

低剂量砷可促进淋巴细胞的体外存活,并可诱导其MT合成增加。

Results:(1) All of the four concentrations (500ug/mL 1000ug/mh 2000ug/ml 4000ug/ml) of RTE could inhibit CEM cell growth characterized by apoptosis characterized by pyknosis, complete nucleic membrane, swollen mitochondria and extended ergastoplasm etc. The apoptosis body was shown at the same time.

结果:(1)500ug/ml、1000ug/ml、2000ug/ml、4000ug/ml的附子提取物均可诱导CEM细胞凋亡,在电镜下可观察,CEM细胞出现核固缩,核膜完整,线粒体肿胀,粗面滤质网扩张等改变,并能发现凋亡小体。

The backbone of sugar residues chain in LBP-4a were contained l-6 indican bond according to periodate oxidation and the results of -elimination reaction indicated that the chain of polysaccharides and protein were connected by O-linked chemical bond.

腑实验证明用含有LBP一4 50 mg一1、100 mg·L-l、200mg.L',和400mg·L-l的培养液培养人肝癌细胞邻Y一7703可显著抑制其增殖;细胞形态学观察发现LBP一4可诱导那Y一7703细胞发生凋亡,使细胞凋亡指数显著提高。

And the antioxidant enzymes were also activated. We found that there was some signaling pathway within the damaged plant and interplant. Diphenylene iodonium, an inhibitor of NADPH oxidase, could significantly inhibit H2O2 burst and enzymes activities that mediated by herbivore-infested. H2O2 has also been proved to play the signal role in defensive response.

茉莉酸信号传导途径在植物防御反应中有着重要的作用,对植株用茉莉酸甲酯熏蒸后,可诱导植株产生与昆虫取食类似的反应--叶片过氧化氢含量有明显的提高,同时对POD、PPO、PAL等直接防御物质有显著的诱导作用,进而证明了茉莉酸甲酯是伤信息在植株间传递的报警信号分子之一。

Hwoever,on third and fifth induced day,mIL-2+B16 PELs and 22.8% and 23.1%cytotoxicity,distinct expression of perforin and granzymeA genes,many granules in cytoplasm.

在这一天〓细胞诱导的PEL与上述结果相同。2.mIL-2〓细胞诱导三天时,取得的PEL则有明显的粒酶A和穿孔素基因表达,其细胞毒活性也达22.8%,电镜下的PEL胞浆中可观察到杀伤颗粒。

Moreover,when pregnant mice were given phenobarbital sodium while exposed to passive smoking,the frequencies of CA,SCE and MN of cells of both maternal and fetal mice increased signifi...

提示孕期被动吸烟对母、胎双方均可造成遗传物质损伤。苯巴比妥钠诱导的高活性混合功能氧化酶系对烟雾中遗传毒性物质可起代谢活化作用。

Results It found that apoptosis was induced in leukemia cells and bcl-2 expression down-regulated by realgar.

结果 雄黄可诱导白血病细胞发生典型的凋亡,同时雄黄可使白血病细胞bcl-2蛋白表达呈时间依赖性下降。

The "regulable osteoinduction microcirculation/microenvironment system in vivo" has characteristics as follows: the culture conditions are controlled. For example, the release of a variety of growth factors can be controlled stably and quantitatively at bone defect site. Early nutrition and revascularization in the center of tissue-engineered bone can be effectively solved; some shortcomings resulted from construction of tissue-engineered bone in vivo, including secondary injury, high level technical requirements, and complex operation, can be avoided; vascularization and osteogenesis can be constructed simultaneously; simple safe and efficient operation.

可调控的体内灌注诱导成骨微循环系统具有以下特点:可以控制诱导培养条件,如调控各种生长因子微量稳定的缓控释放;能有效解决大块组织工程骨中心部位的早期营养和血运重建难题;避免了组织工程骨体内构建存在的二次损伤,需要较高的技术条件、操作较为复杂等缺陷;实现血管化与成骨的同步构建;操作简便,安全高效。

Based on biological experiments, mango glycoside is used as raw material; under the condition with phenol and hydroiodic acid, carbon-carbon bonds are broken to produce the crude product of mango aglycone; the crude product is separated and purified through silica gel column chromatography so that the mango aglycone is separated; the yield rate reaches 12 percent, the purity is higher than 95 percent, and the reproduction performance is good; the IGTT of C57BL/6 normal mice is effectively improved with the norathyriol; and simultaneously the quantity of insulin secretion induced by glucose in vivo for the C57BL/6 normal mice can be improved with the norathyriol.

通过生物学实验证明,本发明所涉及的以芒果苷为原料,在苯酚和氢碘酸条件下,使得碳-碳键断裂,制备得到芒果苷元粗品,再通过硅胶柱层析分离纯化得到芒果苷元的方法使得其产率可达12%、纯度大于95%,且重现性好;norathyriol可使C57BL/6正常小鼠IGTT有明显改善;同时norathyriol可提高C57BL/6正常小鼠体内葡萄糖诱导的胰岛素分泌量。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在,'歼灭战perfuming自己与胡努特,那麼,他来到和SAT 。

The shamrock is the symbol of Ireland and of St.

三叶草是爱尔兰和圣特里克节的标志同时它的寓意是带来幸运。3片心形叶子围绕着一根断茎,深绿色。