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Results all of the 20 x-ray cases demonstrated the trabeculae bone hazy with pathy high density in the weight-supporting zone .all of the ct cases demonstrated the collapse of the femoral head. and the 4 cases demonstrated the high density, fragment of the femoral head and cystic lucency zone in the high density area and mixed density could be seen in 3 cases. the 4 mri cases demonstrated cystic hypointensity in t1wi and hyperintensity in t2wi. the 3 mri cases demonstrated mixed intensity in t1wi and t2wi,the 3 mri cases demonstrated irregular hypointensity with collapse of the femoral head in t1wi and t2wi.

结果 x线平片20 例,均表现为股骨头持重区骨小梁增粗且模糊不清,持重部位呈斑片状或斑点状密度增高影,本组均可见(占100%)。ct扫描20 例,平扫均表现为股骨头形态塌陷,其中显示高密度硬化4 例(占20%),股骨头碎裂,显示高密度区内有不规则透亮区,呈高低混杂密度改变有3 例(占15%)。mri扫描10 例, t1wi呈斑点状或小囊状低信号,t2wi为高信号,本组4 例,t1wi与t2wi均为不规则低、等、高混杂信号,本组3 例,股骨头塌陷、变形,t1wi与t2wi均为不规则形低信号3 例。

objective to study mri diagnostic value on multiple sclerosis.methods mri examination data of 31 patients with multiple sclerosis were analysised retrospectively.results total 184 lesions were detectived in 31 patients.most lesions were located on white watter area beside the lateral ventricle,and a few lesions were located on the spinal cord,cerebellum,brain stem and corpus callosum.the shape of lesion can be circle or ellipse.the lesion showed as slightly long t1 and long t2 signal.the acute stage lesions can have enhancement.conclusions ms have characteristic findings on mri image.mri can show the patholoic changes,and provide strong evidence for clinic diagnosis of multiple sclerosis.

摘 要]目的:探讨多发性硬化(muliplle sclerosis,ms)的mri特征表现及其诊断价值。方法:回顾分析31例临床诊断为ms患者的mri检查资料。结果:31例共发现病灶184个,病灶于侧脑室旁白质区、半卵圆中心及皮层下区最多见,其次见于脊髓小脑、脑干及胼胝体,部分可见视神经受累,病灶呈卵圆形或圆形稍长t1、长t2信号,矢状位像见病灶与侧脑室垂直,急性病灶增强扫描有的可呈结节状、环状或斑点状强化。结论:在mri图像上ms有特征性表现,mri能反应ms病理变化,为临床诊断ms提供可靠依据。

Results: Primary cell and passage cell growed adherently with great reproductive activity; after migration, many living cells can be observed round pin hole, distributed irradiately.

结果:原代、传代细胞贴壁生长,有较强的增殖能力;植入大鼠海马后沿针道及注射区可见多数存活细胞,散在分布,自植入区及针道向周围逐渐减少。

N perifocal tissue intracerebral hemorrhage there were rarefaction neuron,cell spaces augmentation,cell diminution,distinct demarcation of cell membrane and surrounding,and we discovered a lot of degeneration and necrosis nerve cells,cell body collapsed,pycnosis anachromasis,nucleoli disappeared. In EPO group we discovered that center area of hemorrhage shinked,nerve cells of degeneration and necrosis decreased in perifocal tissue,majority cells morphous were normal and pathological changes were light.

CH对照组在术后皮层出血中心无神经元,仅见少量胶质细胞,细胞间质空泡样改变;出血边缘区神经元稀疏,细胞间隙增大,细胞缩小,胞膜与周围分界清楚,并可见大量变性及坏死的神经细胞,表现为胞体皱缩,核固缩深染,核仁消失。rhEPO治疗组出血中心区变小,边缘区神经细胞变性坏死减少,多数存活细胞形态相对正常,病变较轻。

One-sample t test was used in profoundly congenital hearing loss infants and control group,the activated brain areas were:bilateral transverse temporal gyri, superior temporal gyrus,middle temporal gyrus,bilateral insular lobe,bilateral precentral gyrus,postcentral gyrus,bilateral cingulate gyrus,bilateral inferior parietal lobule,bilateral superior parietal lobule,bilateral superior frontal gyrus.

在对极重度感音神经性耳聋患儿和对照组进行组间比较发现,病人组数据减去对照组数据时可见激活的脑区主要有:双侧颞横回、双侧颞上回、双侧颞中回、双侧岛叶、双侧中央前、后回、双侧扣带回、双侧顶下小叶、双侧顶上小叶、双侧额上回等,提示极重度感音神经性耳聋患儿在接受刺激后动用了更多的脑区而且激活强度明显增加。

The choleratoxin B labelled cells distributed in the lateral hypothalamic area,the lateral preoptic area and the arcuate nucleus.

免疫组织化学染色显示,在大鼠下丘脑外侧区、外侧视前区和弓状核都可见CTb标记免疫阳性神经元。

RESULTS: During 10 - 12 weeks, in cuntrol group: The defect area was repaired by white and soft tissue that had no resistance to press. The repaired tissue was still lower than the surrounding articular surface with clear boundary. By histological observation, it was found that the defect was repaired by the mechanism similar to inflammatory reaction and the defect is ultimately filled by the hyperplasia of hyaline degenerative fibrous tissues. In filling group: the defect was repaired by semi-transparent, smooth, textured tissues with polish that had resistance to press as well as elasticity. The repaired tissue was almost similar to the shape of the surrounding cartilage,difficult to be distinguished. After histological observation, it was found that there was no inflammatory reaction, but active hyperplasia of inner bonetissue and cartilage tissues; a lot of osteoid tissues and trabeculation were found. Newlborn cartilage was fused with surrounding cartilage tissue and connected with surrounding tissues.

结果:10~12周,对照组:缺损区由白色、质软、按压无阻抗的组织修复,修复组织仍低于周围关节面,边界仍清晰可辨,组织学以类似炎症反应的机制修复缺损,最终以透明变性的纤维组织的增生来填补缺损部位;填充组:缺损区由半透明状、质韧光滑有光泽,按压有阻抗并有弹性的组织修复,修复组织与周围软骨外形上已基本相似,不易区分,组织学未见有炎症反应的过程,内骨组织和软骨组织增生活跃,并可见大量类骨组织和骨小梁形成,新生软骨和周围软骨组织融合,并与周围组织连接。

ResultsThere was no expression of Caspase-3 in group A. The expression of Caspase-3 in group C was decreased compared with that in group B(P<0.01. In groups B and C, expansion and vacuolization of mitochondria, swollen neurons and apoptotic bodies appeared, which suggested that WBH could induce neuron injury, and the neuron injury in group C was more severe than that in group B.

结果A组大鼠海马区神经元无Caspase-3表达,B、C两组大鼠海马区神经元有Caspase-3表达,B组较C组Caspase-3表达平均灰度值减小。B、C两组大鼠海马神经元超微结构发生改变、细胞器水肿,部分线粒体空化,内质网稀疏,突触前膜、后膜结构不完整,可见自噬体结构;B组大鼠的神经元超微结构损害较C组轻。

To explain relationship between the effect of CLD on senile Demention and neuron in hippocampal area. The change of natural aging mice's neuron in hippocampal area were studied by applying microscope and transilluminating electric microscope. Results: Comparing with the young control, the old control mice's hippocampus had less small pyramid cells, the nerve cells denaturalizing and their branches reducing in the microscope. Hippocampal nerve cells were degenemiceing, with nucleus membrance crinkling like wave shape were not clear, and chromatin condensing with high electron density, heterochromatin accruing, part cell organs inclosing nucleus, nucleus condensing in the EM.

为了阐明菖龙丹抗老年性痴呆作用与海马区神经元结构的关系,运用光镜和透射电镜观察了菖龙丹对自然衰老小鼠海马区形态的影响,结果显示老年对照组小鼠光镜下海马锥体细胞较青年对照组数量减少,细胞体积变小,神经元变性,分枝减少;电镜下海马神经细胞发生退化改变,核膜皱缩,呈波浪状,膜结构不清晰,核染色质浓缩,电子密度高,异染色质较多,部分胞浆细胞器向细胞核聚集,有的可见细胞核固缩。

Apoptosis of myocytes was observed in the peripheral infarcted area, which appeared as shrinkage of cells and a condensation or marginating of chromatin. Large fragmentations and ladder bands were seen in DNA gel electrophoresis.

梗塞边缘区可见凋亡心肌细胞,其形态表现为细胞皱缩,细胞核染色质聚集成块或边集;DNA凝胶电泳可见大片段或梯形带。

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