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Results: In 6 patients the relationship of Broccas area and precentral motor area to the frontal lobe tumor was identified allowing pre-operative neurosurgical planning to minimize language and motor disruption. Diffusion tensor images were corrupted by motion in one patient but successfully demonstrate the impact of tumor on white matter tracts in 5 patients. Fractional anisotropy images, showed disruption of the left arcuate fasciculus in one patient, deviation/deformation in 2 cases and unaffected by tumor in the remaining two cases.

因刺激任务为按键反应模式,5例肿瘤患者双侧均可见初级运动皮质(M1)和辅助运动区的激活,1例因右侧肢体瘫痪而只显示右侧M1的激活。1例患者在DTI扫描过程中头动明显而失败,5例肿瘤患者FA图显示良好,纤维束重建后1例可见弓状束的浸润破坏,2例伴有弓状束变形及移位,2例弓状束未见破坏或移位。

Results: Abnormal signal showed in 15 cases by routine plain scan (66%), while images of normal pituitary gland, infundibulum, and cavernous sinus showed obviously strengthened signals in 21 cases by non dynamic enhanced MRI (92%), with low signal area of microadenoma, forming evident image characters.

结果:常规平扫23例中,有15例可见异常信号改变,占66%;而动态增强扫描后有21例可见正常垂体腺、漏斗、海绵窦逐一明显强化,微腺瘤则尚未强化仍呈低信号区,形成鲜明对比的图像特征,占92%。

ERK positive cell mainly distributed at nucleus of solitary tract, ambigous nucleus, and positive fibers and cells mainly distributed at medullary visceral zone, nucleus of solitary tract and ambigus nucleus. These positive cells formed an isolated zone from nucleus of solitary tract via medullary visceral zone to SP5, which could be seen using immunohistochemical stain. Positive cells and fibers also distributed at the projection from pneumogastric nerve to the stem.

免疫组织学染色可见,阳性细胞主要分布于延髓内脏带的孤束核和疑核、阳性纤维伴随阳性细胞分布于延髓内脏带的孤束核区和疑核、呈沿孤束核经延髓内脏带至三叉神经脊束核的弧行带;在迷走神经向脑干投射部位也可见阳性胞体和纤维的分布。

Small round dark lymphocytes are seen in the submucosa , and there is also hemorrhage.

在黏膜下层可见小圆形染色较深的淋巴细胞,还可见出血区。

The fundamental imaging features of osteosarcoma were showed bone destruction, periosteal reaction, neoplastic bone and soft-tissue mass. Among 49 cases examined by radiography, osteoblastic pattern sarcoma was found in 19 cases, osteolytic pattern sarcoma was found in 13 cases and mixed pattern sarcoma was found in 17 cases. The detection rates of bone destruction, periosteal reaction, soft-tissue mass, neoplastic bone and Codman triangle by radiography were respectively 61.2%, 95.9%, 71.4%, 73.5%and 27.7%. All 10 cases with CT scan were showed bone destruction, soft - tissue mass and neoplastic bone. The detection rates of periosteal reaction,憇ieve sign挶 and Codman triangle with CT scan were respectively 90%, 90% and 11%. The tiny neoplastic bone and"sieve sign"were showed sensitively by CT, but Codman triangle was showed by radiography superior to CT.32 cases with MRI scan presented the normal marrow was replaced by the tumor, which was showed low to intermediate signal intensity on T1-weighted images and promiscuity signal intensity on T2-weighted images. 7 cases presented hemorrhage and 24 cases presented necrosis.

骨肉瘤基本影像表现为骨质破坏、骨膜反应、瘤骨和软组织肿块。49例X线表现为成骨型19例,溶骨型13例,混合型17例;X线对骨质破坏、骨膜反应、软组织肿块、瘤骨和Codman三角的检出率分别为61.2%、95.9%、71.4%、73.5%和27.7%;10例CT表现均可见骨质破坏、软组织肿块及瘤骨,CT对骨膜反应、筛孔征和Codman三角的检出率为90%、90%和11%;CT对显示细小肿瘤骨和筛孔征最敏感,但对Codman三角的显示不如X线平片;32例MRI表现为骨髓腔内正常的骨髓高信号被肿瘤信号所取代,T1WI呈低~等信号,T2WI呈混杂信号,7例合并出血,24例中央坏死囊变,32例增强扫描均呈不均匀强化及瘤周可见水肿区。

Results The main histopathologic changes were:① experimental group: inflammatory cell infiltration (1W); inflammatory cell disappearance, fibroblast and capillary tachyauxesis, osteoid tissue and small amount neoformative bone tissue appearance (2 W); fibrous tissue decrease, neoformative bone tissue enlarging and maturity (1~3 M).

结果① 实验组:术后1周,骨缺损区周围有炎性细胞浸润,可见牙槽骨变性坏死;术后2周,炎性渗出明显吸收,成纤维细胞、毛细血管生长活跃,可见骨样组织和少量骨组织;术后1~3个月,新生骨组织范围扩大,钙化程度加强。

Many osteoid were formed around metal surface and bone graft remodeling was active in 1 month as shown by nondecalcified section.

大体观察可见6个月时三翼臼植骨区表面与正常骨表面相仿,界限不清,可见三翼臼的翼板被骨组织包埋。

Cases 1-5 who presented with spastic paraparesis and other prominent upper motor neurone signs showed high signal on T1-weighted images in the centrum semiovale, corona radiata and posterior limb of the internal capsule which corresponded to the large myelinated fibres of the corticospinal tract Fig.

病例1~5患者表现为下肢痉挛性轻瘫和其他一些明显的上运动神经元症状体征,在T1像上于半卵圆中心、放射冠、内囊后肢处的皮质脊髓束大有髓纤维走行区均可见高信号病灶(图1),在T2、PdWI像上也可见自放射冠延伸至大脑脚的高信号病灶。

Surface-based hippocampal morphologic analysesWe found regional atrophy of the lateral and inferior hippocampus area bilaterally corresponding to the CA1 and subiculum hippocampal subfield and reginal expand in the heads and tails bilaterally in aMCI compared with NC.

基于海马表面的形态分析结果aMCI组双侧海马的外侧及下表面可见区域性萎缩,这些区域相当于组织学上的CA1区和下托,此外在双侧海马的头部及尾部可见局部膨胀。

Of the 12 patients with basal ganglia and/or capsular lesions, one patient had involvement of the caudate nucleus and the adjacent anterior limb of the internal capsule without any other parenchymal abnormality. In the other 11 cases, the posterior limb of the internal capsule alone (n = 4) or together with the external capsule and putamen (n = 3) or with the globus pallidus (n = 4) were affected. In all 11 of these patients, additional MDJ and/or thalamic-hypothalamic lesions were also found.

在12例基底节区和/或内囊受累的患者中,1例患者仅见尾状核及邻近的内囊前肢受累,其余部位均未见病灶;余下11例患者,内囊后肢单独受累4例;内囊后肢、壳核、外囊共同受累3例;内囊后肢同时伴苍白球受累4例;这11例患者除基底节区和/或内囊受累外,均还可见中脑-间脑结合处和/或丘脑-下丘脑区病灶。

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