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The in vivo growth of melanoma could be controlled by OSM secreted from OSM gene-modified cells. The activated Egr-1R by radiation could enhance the expression of OSM and thereby impose an aggravated damage on tumors in vivo, namely brining a dual inhibitory effect of gene and radiation on tumors.

转基因分泌的OSM可对瘤细胞的体内生长产生抑制;射线可通过Egr-1R增强OSM表达的途径加剧肿瘤抑制,即基因与射线的双重抑瘤效果。

Then, the volume and morphology of grafts were observed and proliferating cell nuclear antigen expression of mammary epithelial cells in grafts was detected by immunohistochemistry. Experiment two: From 2 to 6 weeks after implanting, B-E〓 or NH1996 with respective dosage of 20ug and 100ug were injected muscularly into four groups of host mice once two days, and the control group was designed without treated with hormone.

结果:1。植入2周和6周乳腺组织形态结构保持完整,植入2周乳腺组织块体积、腺体数目和增殖程度均较植入时明显降低,并以此水平维持至植入6周。2.B-〓对植入的乳腺组织形态学无明显影响,但可引起乳腺上皮细胞PCNA、Bcl-2蛋白表达的升高;B-〓可上调PR,下调ER,说明植入裸鼠的正常乳腺对B-〓有反应,证实模型建立成功。

In the study, Pristane was been used with recombinant BLyS and BLC vector those can expressed in vivo in mice, the influence to SLE-like disease was investigate. Pristane associated with BLyS or BLC aggravates proteinuria. This fact indicates that the abnormal expression of the two genes has definite effect on mice lupus-like disease process.

本研究中,当Pristane与可在体内表达的重组BLyS或BLC基因质粒合用时,小鼠的蛋白尿明显加重,表明这两个基因的异常表达对小鼠的狼疮样病变过程有明显的影响。

Furthermore, in light of the φ-mapping theory the SU (2) Chern density is expressed as δ, and the zero points of 〓 field are characterized by the φ-mapping topological numbers—the Hopf indices and the Brouwer degrees.

进一步,利用Φ-映射理论作者证明SU(2)陈密度可表达成δ的形式,并阐明Φ场零点的拓扑特征可由Φ-映射拓扑数—Hopf指标和Brouwer度所表征。

Toponym placement is one element of the map, it can be associated with the various Geo-spatial features linked to the attributes. Moreover a reasonable distribution of toponym placement will directly affect the information that a map contain.

地名注记是地图的组成要素之一,它可与各的空间地物属性相关,而注记配置的合与否将直接影响到地图上所要表达的资讯,可其重要性。

The present invention relates to a process of producing a functional immunoglobulin superfamily protein, which has at least one disulphide bond when functional, the process comprising the steps of providing a bacterial cell comprising a gene coding for the protein, the gene is expressible in said cell, cultivating the cell under conditions where the gene is expressed, isolating the protein from the cell without reducing it, and subjecting the isolated protein to a folding treatment.

本发明涉及一种产生功能性免疫球蛋白超家族蛋白的方法,此蛋白质在有功能时具有至少一个二硫键,此方法包括如下步骤:提供一种包含编码此蛋白质的基因且此基因可在其中表达的细菌细胞;在使此基因表达的条件下培养此细胞;从该细胞中分离出此蛋白质而不还原它;以及使分离出的蛋白质经受折叠处理。

Such MCF-7 cells were then cocultured with TILs isolated from fresh tumor samples and their apoptosis was assessed by JAM test. Results ...

BCL - 2表达的乳腺癌细胞可对抗肿瘤浸润淋巴细胞的免疫攻击,BCL - 2SON可作为治疗乳腺癌的新途径。

We anticipate that genetic variation in MIF expression may impact on the response of the human heart to ischaemia by the AMPK pathway, and that diagnostic MIF genotyping might predict risk in patients with coronary artery disease.

我们认为,MIF表达的遗传变异可通过AMPK途径影响心脏对缺血的反应,从而通过诊断MIF基因型可预测冠心病患者的危险性。

The levels of E2F1 proteins could return to normal at 2h and 16h in high MOI infected cells treated with large dosage of allitridin.⑤The effects of allitridin on regulating the transcription and expression of dhfr gene in HCMV infected cells: The higher transcription of dhfr gene of high MOI infected cells within 4-16h was partially or wholely antagonised by allitridin. The up-regulated dhfr mRNA levels of low MOI infected cells nearly returned to normal after allitridin treatment.

大蒜新素处理HCMV感染细胞对E2F蛋白表达的影响:大蒜新素处理低MOI和高MOI感染细胞可使病毒诱导上调的E2F蛋白表达水平下调,大剂量药物处理高MOI感染细胞2h和16h时E2F蛋白回复至正常细胞水平,其作用特点为:药物对高MOI感染细胞的拮抗作用优于对低MOI感染细胞的处理;大剂量药物作用优于中剂量药物;对病毒在感染早期(16h内)诱导效应的拮抗作用强于对病毒感染中期(24h)诱导效应的拮抗。

The expression of EL in endothelial cells may play a role in the progression of CAD. The EL+/CECs may be a good prognostic factor. EL+/CECs together with hsCRP may increase the prognostic value.快车资源xn XtTnt_Ahx

冠心病患者血管内皮细胞表达的EL可能参与了冠心病发病,EL+/CECs可作为冠心病临床预后的预测因子,联合使用EL+/CECs与hsCRP可显著提高冠心病患者预后的预测效率。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。