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"Work" means the literary and/or artistic work offered under the terms of this License including without limitation any production in the literary, scientific and artistic domain, whatever may be the mode or form of its expression including digital form, such as a book, pamphlet and other writing; a lecture, address, sermon or other work of the same nature; a dramatic or dramatico-musical work; a choreographic work or entertainment in dumb show; a musical composition with or without words; a cinematographic work to which are assimilated works expressed by a process analogous to cinematography; a work of drawing, painting, architecture, sculpture, engraving or lithography; a photographic work to which are assimilated works expressed by a process analogous to photography; a work of applied art; an illustration, map, plan, sketch or three-dimensional work relative to geography, topography, architecture or science; a performance; a broadcast; a phonogram; a compilation of data to the extent it is protected as a copyrightable work; or a work performed by a variety or circus performer to the extent it is not otherwise considered a literary or artistic work.

本著作」指依据本授权条款提供的文学及艺术创作，包含但不限於以任何方式或形式表达之文学、科学及艺术范围之制作物，例如：书籍、小手册及其他撰著；演讲、演说、布道及其他类似同性质之著作；戏剧著作或歌剧著作；舞蹈著作或默剧；含歌词或不含歌词之音乐作曲；电影著作及其他藉由与电影摄影技术类似之程序表达之同类著作；素描、绘画、建筑、雕塑、雕刻或版画之著作；摄影著作及其他藉由与摄影技术类似之程序表达之同类著作；应用艺术著作；插图、地图、设计图、素描及地理、地形、建筑或科学相关立体著作；表演；广播；录音物；和可受著作权保护的资料编辑；或不属於文学或艺术创作的各式表演人或马戏团表演人所表演的创作。

The innovations of this paper as follows:(1)The topological relation model between complex spatial objects is brought forward, which represented by some composite basic 9I matrix and results in general signification.(2)Time and space integrated topological model is suggested to reason about spatio-temporal change types;(3)Sweep-line algorithm is improved, and a new little circles of polyline nodes overlapped with region method is proposed. As result, it's efficient to calculate line-line, line-region and region-region topological relations.

本文的创新之处在于提出了一种能够描述复杂对象的数学表达模型，将复杂对象间的复合拓扑关系表示成基本拓扑关系的组合，具有一定的普适意义；研究了时空拓扑关系的内涵和表达方法，说明利用时空拓扑关系可隐性地实现时空变化语义的查询；对平面扫描线法进行了改进，提出了一种新的节点微小圆求交的算法，可有效地解决线面、线线、面面拓扑关系的计算问题。

Suppression of metastatic hemangiosarcoma by a parvovirus MVMp vector transducing the CXCL10 chemokine into immunocompetent mice.

2.2 转染细胞表达CXCL10蛋白的检测采用Western blot分别检测转染CXCL10表达载体的细胞及其培养上清中CXCL10的表达，均可检测到CXCL10蛋白；而转染空载体组和未转染组细胞均未能检测到CXCL10存在

The result showed that Insulin capsule could increase the insulin sensitivity of model rat of insulin resistance of typeⅡdiabetes mellitus by decreasing its blood sugar,decreasing its avoirdupois,improving its lipodystrophy and hemodynamics , increasing its GLUT4 translocation of skeletal muscle cell,increasing expression level of GK in liver cell, increasing expression level of PEPCK and decreasing level of TNF-αexpression in adipose tissue.

结果表明，胰苏灵胶囊可使2型糖尿病IR模型大鼠的血糖降低、体重减轻、脂质代谢异常得到改善、血流变异常得到改善；能使模型大鼠的脂肪组织TNF- a的mRNA表达水平降低，能使模型大鼠骨骼肌细胞的GLUT4的转位增加，能增加肝GK表达，能诱导PEPCK的转录。通过以上作用，胰苏灵胶囊可使2型糖尿病IR大鼠模型的IR得到改善。

Results(1) Group of electroacupuncture in Shu and dense wave can significantlyreduce the degree of ankle swelling(P＜0.05, P＜0.01), which shows thatelectroacupuncture has obvious anti-inflammatory and repercussive roles;(2) Theresults of HE staining showed that group of electroacupuncture in Shuand dense wave can significantly reduce inflammatory cell infiltration,inhibit synovial cell proliferation, and decrease proliferation of granulationtissue in rats joints;(3) group of electroacupuncture in dense-wave can increase the pain thresholdof experimental rats (P＜0.05, P＜0.01), reduce the content of peripheral painmediums, such as K~+, DA and 5-HT(P＜0.05, P＜0.01), which shows thatelectroacupuncture has significant analgesic effect;(4) In the local lesion of joints, electroacupuncture can significantly reducethe content of IL-1β, IL-8, TNF-a, increase IL-4 content, decrease theexpression of COX-2mRNA, and significantly promote the expression ofHSP-70 protein in synovial tissues of acute gouty arthritis rats (P＜0.05,P＜0.01),thus restrain the occurrence of synovial tissue inflammation.

结果：(1)电针疏密波组能显著减轻踝关节肿胀度(P＜0.05，P＜0.01)，表明电针有明显的抗炎消肿作用；(2)HE染色显示：电针疏密波组可使大鼠关节炎症细胞浸润明显减轻，滑膜细胞增生明显被抑制，肉芽组织增生明显减少；(3)电针密波组能提高实验性大鼠痛阈(P＜0.05，P＜0.01)，降低外周疼痛介质K~+、DA、5-HT的含量(P＜0.05，P＜0.01)，表明电针有明显的镇痛作用；(4)在病变关节局部，电针能显著降低急性痛风性关节炎大鼠滑膜组织IL-1β、IL-8、TNF-α含量(P＜0.05，P＜0.01)，升高IL-4的含量(P＜0.05，P＜0.01)，并降低关节滑膜内COX-2mRNA的表达(P＜0.05，P＜0.01)，可促使急性痛风性关节炎大鼠滑膜内HSP-70蛋白表达显著增加(P＜0.05，P＜0.01)，从而抑止滑膜组织炎症发生。

Deduced by the proportion of typical sterile plants and normal fertile plants in segregative generations derived from WA zhenqiuA/6078 that:I gene could inhibit the expression of Rf gene completely by the heterozygosity of 1 pair of Rf in genotype;and only reduce the expression of Rf genes with two heterozygous Rf genes in genotype ;but it would never inhibit the expression of Rf genes if the genotype included 3 pairs of heterozygous Rf genes. When Rf gene was homozygous,the / gene could not inhibit the expression of it.

根据认叭真秋刀6078各衍生分离世代中典型不育株和正常可育株所占比例推断：基因型中仅包含1对杂合的Rf基因时，I对Rf的表达起完全抑制作用；基因型中包含2对杂合的Rf基因时，I仅对Rf的表达起削弱作用；当基因型中包含3对杂合的对基因时，I对Rf的表达不起抑制作用；I对纯合位点的Rf的表达不起抑制作用。

Hideyuki Doi, Nakui Madaki, Hrroshi, Hiromichi Komatsu, Keisei Fujimori and Susumu Satomi Tohoku. A New Preadipocyte Cell Line,AP-18,Established from Adult Mouse Adipose Tissue. J.Exp.Med,2005,207:209-216[2] Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPARγ 2, a lipid-activated transcription factor. Cell ,1994,79:1147－1156

PPARα调节脂肪代谢的机制总结如下：肝脏脂肪酸水平的增高激活PPARα，然后转录激活参与脂肪酸氧化的基因；配体与之结合后可激活编码乙酰辅酶A合成酶的基因，同时PPARα激活后可调节脂肪转运相关基因的表达如PPARα升高高密度脂蛋白和抑制ApoC－Ⅲ的表达。

The mc2155 carrying pMind-glmU-AS was induced by different concentration of tetracycline, and GlmU protein was detected in the mc2155 carrying pMind-glmU-AS by Western blotting. The results showed that tetracycline of 20ng/ml has obviously inhibited the growth rate of mc2155 carrying pMind-glmU-AS, but the amount of GlmU protein did not change compared to that of uninduced mc2155 carrying pMind-glmU-AS.

glmU反义RNA的诱导表达与GlmU蛋白的检测分别用5 ng/ml、10 ng/ml和20 ng/ml的四环素诱导携带pMind-glmU-AS表达载体的mc~2155菌株表达反义RNA，绘制细菌生长曲线，结果表明20 ng/ml浓度的四环素可抑制mc~2155/pMind-glmU-AS的生长，但Western Blotting分析结果显示经四环素诱导和未诱导的mc~2155/pMind-glmU-AS中，GlmU蛋白表达量无明显的变化。

The infection of EBV may transform the infected cells by immortalizing them and the expression of the virus encoded proteins LMP-1 may activiate the expression of c-myc.

一myc的表达有显著影响，提示EB感染细胞后其编码的LMP一1可促进细胞的增生和转化，经过信号传导及附加的基因突变，最终可激活并促进c一myc的高表达，导致NHL 等相关疾病的发生。

Results:(1) The rats produced amphetamine CPP after treated with 2 mgkg^(-1) amphetamine for 4 days. Ketamine and low, middle, high dose rhynchophylline all could eliminate the CPP effect, and the effect of rhychophylline was increased in a dose-dependent manner. Rhychophylline itself could not induce CPP in normal rats.(2) When compared with normal rats, the NR2B expression in nucleus accubens and amygdaloid of the model rats was obviously increased. Ketamine and middle, high dose rhynchophylline could decrease NR2B expression induced by amphetamine, while low dose rhynchophylline did not affect NR2B expression. Rhynchophylline had no effect on RN2B expression in normal rats.

结果：(1)建立了苯丙胺（2mgkg^(-1)，连续4d）诱导的位置偏爱模型，氯胺酮及钩藤碱低、中、高剂量均可消除苯丙胺诱导的位置偏爱效应，随钩藤碱剂量增加其效应加强，且本身无精神依赖性；(2)苯丙胺模型组大鼠伏核和杏仁核NR2B蛋白表达增加，氯胺酮及钩藤碱中、高剂量抑制NR2B表达，低剂量及本身对NR2B表达无影响。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。