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"This study raises the possibility that androgen replacement therapy might lower the risk for Alzheimer's, but this is far from proen," says Sam Gandy, MD, PhD, chair of the Alzheimer's Association's Medical and Scientific Adisory Council and director of the Farber Institute for Neurosciences at Thomas Jefferson Uniersity."Because testosterone is rapidly conerted to estrogen after entry into neurons, the new data are logical, and they doetail well with historical data."

"这项研究增加了雄激素补充疗法降低阿尔次海默危险性的可能,但是里真正的证实路还很长,"阿尔次海默医学协会和科学咨询委员会的**,Thomas Jefferson大学的神经病学Farber协会的主任,医学博士,公共卫生学博士Sam Gandy说,"因为雄激素在进入神经元后迅速降解为雌激素,新的研究资料还有局限性,然而他们的研究结果与历史上研究的结果很吻合。"

Mechanistically, the photocatalytic processes are based on the electron transfer from a excited dyes to the conduction band of TiO〓 semiconductor and subsequent some reactions such as the further reaction of injected electrons with adsorbed oxygen and complicated decomposition processes of dye cationic radicals to lead to dye degradation or mineralization, which offers a feasibility of utilizing inexpensive visible light or most part of solar spectra to treat dye pollutants.

其光催化过程的机理为:染料在可见光下被激发,电子从激发态染料传输到TiO〓半导体的导带,随后发生一系列的反应,如注入的电子与吸附的氧反应以及染料正碳自由基复杂的分解反应导致了染料的降解和矿化,这就为利用廉价的可见光或太阳光中的大部分可见光谱来处理染料污染物提供了可能。

The prolyl hydroxylase inhibitor DMOG inhibited apoptosis and cell death induced by serum deprivation in MSCs concurrent with HIF-1αstabilization, mitochondrial protection,and activation of the PI3K/Akt pathway.

实验结论:1、DMOG能够降低MSCs内HIF-1α的降解和上调下游Glut-1的表达,在作用浓度下对MSCs没有明显的毒性作用;2、DMOG能够降低缺血清状况下MSCs的凋亡和死亡;3、caspase-3依赖的和非依赖的线粒体通路可能在DMOG对MSCs保护中发挥了一定的作用;4、PI3K/Akt通路在DMOG对MSCs的保护中发挥了重要的作用。

The results showed:(1) The histological changes of KC were in fact a wound-repair process;(2) The increased melanin in KC coordinated with "multi-overlapping screen" effect, a result of multiple layers of "supranuclear cap", was the direct cause of hyperpigmentation of the graft and (3) The hydrolytic disturbance of melanin in KC and the longer life span of the KC were probably the important reasons for the increase of melanin in the epidermis.

结果表明,角朊细胞的组织学改变实际上是一个损伤后修复的过程;角朊细胞内黑色素含量增加及出现的多层次的&核上帽&状分布而形成的&多重帘幕&效应,是皮片过度色素化的直接原因;黑色素在角朊细胞内的降解障碍及角朊细胞更新周期延长可能是表皮内黑色素含量增多的重要原因。

After overcoming the flux shift during the process, the production ability of strains could be the limiting factor for further increasing the production. To avoid the random modification on strains, the comprehensive enzymatic study of nucleoside producing-pathway was conducted on four strains with different producing ability. And the results could be used to direct further reconstruction of strains. It was also found that nucleotidase was of much importance to nucleoside production.

在成功克服了代谢流的迁移之后,菌株的代谢能力可能成为了进一步提高产率的限制因素,为了避免对生产菌的进一步改造中的盲目性,对四株不同菌株间嘌呤途径关键酶活力的系统测定,对肌苷、鸟苷生产菌种的酶学特征有了全面的了解;并发现了核苷降解酶对于核苷生产能力至关重要;酶学特性研究对肌苷、鸟苷生产菌的进一步改造提供了方向。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。